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  • 1
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    Online Resource
    Exploratory Case‐Control Analysis of Psychosocial Factors and Adult Periodontitis
    Wiley ; 1996
    In:  Journal of Periodontology Vol. 67, No. 10S ( 1996-10), p. 1060-1069
    Details
    In: Journal of Periodontology, Wiley, Vol. 67, No. 10S ( 1996-10), p. 1060-1069
    Abstract: W e explored the association between social factors and adult periodontitis by comparing self‐reported information for daily strains and symptoms of depression in 71 cases and 77 controls. Cases and controls were selected from among 1,426 participants in the Erie County Risk Factor Study. We found differences among those who scored higher than their peers on measures of social strain. The odds ratio (OR) and 95% confidence interval (95% CI) for the association between case status and Role Strain score of 2.27 or more was 2.84, 95% CI = 1.08 to 7.46. We also examined serum antibody, dichotomized at the median, for three periodontal pathogens ( Bacteroides forsythus [IgG Bf], Porphyromonas gingivalis [IgG Pg] , Actinobacillus actinomycetemcomitans [IgG Aa] ), and assessed interaction between antibody levels and a Depression score derived from the Brief Symptom Inventory. IgG Pg and IgG Aa were both strongly associated with case status (OR = 4.52, 95% CI = 1.99 to 10.3 and OR = 5.29, 95% CI = 2.34 to 12.0, respectively). IgG Bf was associated with periodontal disease but only among individuals who had higher scores for Depression (OR = 6.75, 95% CI = 1.25 to 36.5). Smoking status was associated with case status (OR = 4.95, 95% CI = 1.86 to 13.2). We assessed these findings prospectively by examining factors associated with more extensive disease among the 71 case subjects after 1 year of follow‐up. We found baseline smoking status and IgG Bf among individuals scoring high on Depression at baseline to be associated with more extensive disease (8.1% or more of the sites showing further breakdown). In this population an elevated Depression score may be a marker for social isolation, which could play a role in immune function during periods of social strain. This exploratory analysis has served to identify specific lines of inquiry concerning psychosocial measures as important environmental factors in adult periodontitis. J Periodontol 1996;67:1060–1069 .
    Type of Medium: Online Resource
    ISSN: 0022-3492 , 1943-3670
    URL: Article
    DOI: 10.1902/jop.1996.67.10s.1060
    Language: English
    Publisher: Wiley
    Publication Date: 1996
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  • 2
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    Axial relationship between dental implants and teeth: A radiographic study
    American Academy of Implant Dentistry ; 2012
    In:  Journal of Oral Implantology ( 2012-09-10), p. 120910092905008-
    Details
    In: Journal of Oral Implantology, American Academy of Implant Dentistry, ( 2012-09-10), p. 120910092905008-
    Type of Medium: Online Resource
    ISSN: 0160-6972 , 1548-1336
    URL: Article
    DOI: 10.1563/AAID-JOI-D-12-00052.1
    Language: English
    Publisher: American Academy of Implant Dentistry
    Publication Date: 2012
    detail.hit.zdb_id: 2139588-3
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  • 3
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    Clinical and Patient-Related Outcomes of a Tapered Implant System With Switched Platform Conical Abutments: A Private Practice Field Trial
    American Academy of Implant Dentistry ; 2018
    In:  Journal of Oral Implantology Vol. 44, No. 5 ( 2018-10-01), p. 326-329
    Details
    In: Journal of Oral Implantology, American Academy of Implant Dentistry, Vol. 44, No. 5 ( 2018-10-01), p. 326-329
    Abstract: The aim of this prospective cohort observational field trial was to examine 1-year survival and success rates of a recently introduced tapered implant system with switched platform conical abutments and to evaluate patient related outcomes of therapy. Partially edentulous patients aged between 18 and 75 years, with available bone height for dental implants ≥10 mm desiring to restore the missing tooth/teeth with implant supported restoration, were recruited by 7 periodontists in their respective private practices. Dental implants were installed according to standard implant therapy protocol. Three to 6 months postoperatively, after evaluating interim implant success, implants were restored by the referring dentists. Patient, Ramfjord teeth, and implant data, including baseline and 1-year postoperative, were collected. A total of 60 patients were recruited and received 117 implants. Complete 1-year clinical and radiographic data were available for 83 and 65 implants, respectively. Two implants failed during the first year, resulting in a 1-year survival rate of 98.3%. Mean implant probing pocket depth was 2.29 ± 0.84 mm. Mean radiographic bone distance from implant's shoulder at the mesial and distal sites at 1 year was 0.66 ± 0.5 and 0.79 ± 0.64mm, respectively, resulting in a success rate of 95.4%. Patient subjective evaluation of therapy exhibited a median pain experience of 1 and median esthetics, function, and general satisfaction evaluation of 10 on a scale of 1 to 10. The tapered conical connection dental implant system, used in private dental practices, shows good 1-year survival and success rates that are similar to other implant systems on the market.
    Type of Medium: Online Resource
    ISSN: 0160-6972 , 1548-1336
    URL: Article
    DOI: 10.1563/aaid-joi-D-18-00005
    Language: English
    Publisher: American Academy of Implant Dentistry
    Publication Date: 2018
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  • 4
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    Antibiotic susceptibility of Aggregatibacter actinomycetemcomitans JP2 in a biofilm
    Informa UK Limited ; 2013
    In:  Journal of Oral Microbiology Vol. 5, No. 1 ( 2013-01-01), p. 20320-
    Details
    In: Journal of Oral Microbiology, Informa UK Limited, Vol. 5, No. 1 ( 2013-01-01), p. 20320-
    Type of Medium: Online Resource
    ISSN: 2000-2297
    URL: Article
    DOI: 10.3402/jom.v5i0.20320
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 2013
    detail.hit.zdb_id: 2523919-3
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  • 5
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    The Effect of Smoking and Periodontal Treatment on Salivary Composition in Patients With Established Periodontitis
    Wiley ; 1999
    In:  Journal of Periodontology Vol. 70, No. 10 ( 1999-10), p. 1240-1246
    Details
    In: Journal of Periodontology, Wiley, Vol. 70, No. 10 ( 1999-10), p. 1240-1246
    Abstract: Background: The purpose of this study was to evaluate the effect of smoking on the periodontal status and the salivary composition in subjects with established periodontitis before and after periodontal therapy. Methods: Our study group included 26 healthy subjects, 12 smokers and 14 non‐smokers with established periodontitis. Clinical measurements and non‐stimulated whole saliva were obtained and analyzed at baseline and after scaling and root planing. Smokers presented at baseline with significantly greater probing depth (4.16 ± 0.26) compared to non‐smokers (3.52 ± 0.32) which was statistically significant ( P = 0.0268); likewise, baseline clinical attachment level was greater in smokers (4.49 ± 0.31 compared to non‐smokers 3.87 ± 0.13; P = 0.0620). Mean plaque index was also greater in smokers compared to non‐smokers (0.86 and 0.65, respectively; P = 0.0834). Baseline pretreatment sodium values were significantly greater in non‐smokers (14.36 mEq/l compared to 9.31 mEq/l in smokers; P = 0.0662); likewise non‐smokers exhibited 50% greater salivary calcium levels (6.04 mg/100 ml compared to 4.32 mg/100 ml in smokers; P = 0.0133). Results: Post‐treatment probing depth and clinical attachment level were not different between smokers and non‐smokers; this in spite of significant difference in plaque index in smokers (0.35 compared to 0.13 in non‐smokers; P = 0.0135). Post‐treatment, smokers had reduced calcium concentration (3.58 mg/100 ml compared to 5.11 mg/100 ml in non‐smokers; P = 0.0438). Treatment affected albumin level in smokers only, consequently non‐smokers had significantly greater salivary albumin concentration (1.1 mg/100 ml compared to 0.38 mg/100 ml in smokers; P = 0.0274). Conclusions: Subjects with established periodontitis exhibited elevated concentrations of salivary electrolytes and proteins. Within this study group, smokers exhibited greater disease level but reduced sodium, calcium, and magnesium concentrations. Smokers responded favorably to treatment. The clinical improvement eliminated the differences in salivary composition. J Periodontol 1999;70:1240‐1246.
    Type of Medium: Online Resource
    ISSN: 0022-3492 , 1943-3670
    URL: Article
    DOI: 10.1902/jop.1999.70.10.1240
    Language: English
    Publisher: Wiley
    Publication Date: 1999
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  • 6
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    Radiographic and Clinical Responses to Periodontal Therapy
    Wiley ; 1998
    In:  Journal of Periodontology Vol. 69, No. 5 ( 1998-05), p. 590-595
    Details
    In: Journal of Periodontology, Wiley, Vol. 69, No. 5 ( 1998-05), p. 590-595
    Abstract: M echanical periodontal therapy is widely used for a variety of periodontal conditions. While the clinical efficacy of this treatment has been validated, the radiographic response has not been studied in depth. The purpose of the present study was to examine the clinical and radiographic response to mechanical periodontal therapy, and assess the factors associated with these changes. One hundred and eight patients, with established periodontitis, received oral hygiene instruction and mechanical periodontal therapy for a period of 4 to 5 weeks. Scheduled maintenance visits were performed at 3, 6, 9, and 15 months. Probing depth (PD) and attachment level (AL) measurements were performed at baseline, and at 3 and 15 months. Intraoral radiographs were taken at baseline and 12 to 15 months postsurgery using a Rinn alignment system. Alveolar eresiai height (ACH) measurements were performed on a pair of digitized images of the previously taken radiographs. An overall mean of patients' changes for PD, AL, and ACH was initially computed. Active sites (gainers and losers) were determined using a threshold method, and expressed as patient's percentage of active sites (number of active sites of the total sites measured in each patient). Mean overall probing reduction and AL gain was 0.5 mm and 0.44 mm, respectively. Of all sites measured, 16.6% exhibited AL gain, while only 6.2% of all sites exhibited AL loss. Mean overall change in ACH was −0.07 mm, of which 11.8% of all sites exhibited ACH gain, while 15.1% exhibited loss beyond the threshold. Non‐smokers presented no change in bone loss, while smokers continued to lose bone at an annual rate of 0.17 mm. despite treatment ( P 〈 0.005). Likewise, the average percent of sites per patients showing attachment gain beyond the threshold were much greater in non‐smokers (13.9%) compared to 9.0% in smokers ( P 〈 0.01). Mean probing reduction was 50% greater among non‐smokers (0.6 mm) when compared to smokers (0.4 mm), which was also statistically significant ( P 〈 0.05). A positive and significant correlation was established between the percentage of sites with AL gain and sites with ACH gain (Rho = 0.40; P = 0.0001). It is suggested that monitoring sites for AL and ACH gain expressed as changes beyond a selective threshold is an important outcome variable in treatment studies. J Periodontol 1998;69:590–595 .
    Type of Medium: Online Resource
    ISSN: 0022-3492 , 1943-3670
    URL: Article
    DOI: 10.1902/jop.1998.69.5.590
    Language: English
    Publisher: Wiley
    Publication Date: 1998
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  • 7
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    Online Resource
    Comparison of clinical, radiographic and immunological parameters of teeth and different dental implant platforms
    Wiley ; 2006
    In:  Clinical Oral Implants Research Vol. 17, No. 6 ( 2006-12), p. 658-665
    Details
    In: Clinical Oral Implants Research, Wiley, Vol. 17, No. 6 ( 2006-12), p. 658-665
    Type of Medium: Online Resource
    ISSN: 0905-7161 , 1600-0501
    URL: Issue
    URL: Article
    DOI: 10.1111/clr.2006.17.issue-6
    DOI: 10.1111/j.1600-0501.2006.01282.x
    Language: English
    Publisher: Wiley
    Publication Date: 2006
    detail.hit.zdb_id: 2027104-9
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  • 8
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    Mesenchymal stem cells combined with barrier domes enhance vertical bone formation
    Wiley ; 2013
    In:  Journal of Clinical Periodontology Vol. 40, No. 2 ( 2013-02), p. 196-202
    Details
    In: Journal of Clinical Periodontology, Wiley, Vol. 40, No. 2 ( 2013-02), p. 196-202
    Type of Medium: Online Resource
    ISSN: 0303-6979
    URL: Article
    DOI: 10.1111/jcpe.12044
    Language: English
    Publisher: Wiley
    Publication Date: 2013
    detail.hit.zdb_id: 2026349-1
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  • 9
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    Human blood‐derived endothelial progenitor cells augment vasculogenesis and osteogenesis
    Wiley ; 2015
    In:  Journal of Clinical Periodontology Vol. 42, No. 1 ( 2015-01), p. 89-95
    Details
    In: Journal of Clinical Periodontology, Wiley, Vol. 42, No. 1 ( 2015-01), p. 89-95
    Abstract: Endothelial progenitor cells ( EPC ) participate in angiogenesis and osteogenesis, therefore, have the potential to enhance extra‐cortical bone formation. Aim To enhance extra‐cortical bone formation following local transplantation of human peripheral blood‐derived EPC ( hEPC ) in a guided bone regeneration (GBR) nude rat calvaria model. Materials and Methods hEPC were isolated from peripheral blood of healthy volunteers. Cells were cultured and characterized by flow cytometry for specific endothelial markers. Following exposure of nude rat calvaria, gold domes were filled with 10 6 hEPC mixed with β TCP ( n  = 6). Domes filled with β TCP served as control ( n  = 6). Rats were sacrificed after 3 months. New bone formation and blood vessel density were analysed by histology and histomorphometry. Transplanted hEPC were located in the regenerated tissue using immunohistology. Results Abundant vasculature was observed adjacent to the newly formed bone. According to histomorphometric analysis: blood vessel density was 7.5 folds higher in the hEPC compared with the control group. Similarly, gained extra‐cortical bone height (2.46 ± 1.1 mm versus 0.843 ± 0.61 mm, p  = 0.01) and bone area fraction (19.42 ± 7.48% versus 4.81 ± 3.93%, p  = 0.001) were elevated following hEPC transplantation. Moreover, hEPC expressing human‐specific CD31 were integrated into blood vessel walls adjacent to newly formed bone. Conclusion In nude rat GBR calvaria model, transplantation of hEPC significantly enhanced vasculogenesis and osteogenesis.
    Type of Medium: Online Resource
    ISSN: 0303-6979 , 1600-051X
    URL: Issue
    URL: Article
    DOI: 10.1111/jcpe.2015.42.issue-1
    DOI: 10.1111/jcpe.12325
    Language: English
    Publisher: Wiley
    Publication Date: 2015
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  • 10
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    The association between shallow vestibular depth and peri‐implant parameters: a retrospective 6 years longitudinal study
    Wiley ; 2016
    In:  Journal of Clinical Periodontology Vol. 43, No. 3 ( 2016-03), p. 305-310
    Details
    In: Journal of Clinical Periodontology, Wiley, Vol. 43, No. 3 ( 2016-03), p. 305-310
    Abstract: The aim of this study was to retrospectively evaluate the association between shallow vestibular depth ( VD ) and peri‐implant parameters. Material and Methods Peri‐implant parameters were evaluated in 61 periodontal patients under regular supportive periodontal therapy. Clinical parameters included gingival index ( GI ), plaque index ( PI ), bleeding on probing ( BOP ), peri‐implant pocket depths ( PPD ), mucosal recession ( MR ), relative attachment level ( RAL ), width and thickness of keratinized mucosa ( KMW , KMT ) and VD . Radiographic bone level ( RBL ) was measured on peri‐apical radiographs. Results Sites with shallow VD (≤4 mm) were associated with higher MR (0.91 mm versus 0.47 mm, p  ≤ 0.009), higher RAL (4.23 mm versus 3.59 mm, p  ≤ 0.0001) and higher RBL (2.18 mm versus 1.7 mm, p  = 0.05) when compared with adequate vestibular depth sites ( VD 〉 4 mm). Moreover, sites with shallow VD presented lower KMW compared with sites with adequate VD (1.24 mm versus 2.38 mm, respectively, p  ≤ 0.0001). Slightly greater BOP , and GI were recorded for the shallow VD compared with adequate sites. According to multivariate analysis, factors that could predict RAL included: VD , GI , age, supporting periodontal therapy, implant type and design. Conclusions Based on this study, inadequate vestibular depth around dental implants may be associated with increased peri‐implant bone loss and mucosal recession. Further prospective and intervention studies will be required to fully understand this phenomenon.
    Type of Medium: Online Resource
    ISSN: 0303-6979 , 1600-051X
    URL: Issue
    URL: Article
    DOI: 10.1111/jcpe.2016.43.issue-3
    DOI: 10.1111/jcpe.12504
    Language: English
    Publisher: Wiley
    Publication Date: 2016
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