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  • 1
    Online Resource
    Online Resource
    Isolation, Screening, and Degradation Characteristics of a Quinclorac-Degrading Bacterium, Strain D, and Its Potential for Bioremediation of Rice Fields Polluted by Quinclorac
    American Society for Microbiology ; 2021
    In:  Microbiology Spectrum Vol. 9, No. 2 ( 2021-10-31)
    Details
    In: Microbiology Spectrum, American Society for Microbiology, Vol. 9, No. 2 ( 2021-10-31)
    Abstract: Quinclorac (QNC) is a persistent, highly selective, hormonal herbicide of low toxicity. QNC accumulates in soil and affects the growth and development of crops planted subsequent to its application. In this study, we isolated and screened a QNC-degrading bacterial strain, strain D, from rice paddy soil. Morphological analysis, physiological and biochemical tests, and 16S rRNA gene sequencing led us to identify strain D as a Cellulosimicrobium cellulans strain. We investigated the characteristics of strain D in relation to QNC degradation. Under optimal culture conditions, the QNC degradation rate was 45.9% after 21 days of culture. QNC degradation by strain D in the field was modeled and quantified by a pot experiment. The results show that strain D promotes rice growth and degrades QNC. This research has identified a new bacterial species that degrades QNC, providing a foundation for further research into QNC remediation. IMPORTANCE QNC-degrading bacteria have been isolated from different environments, but there are no reports of Cellulosimicrobium cellulans strains that degrade QNC. In this study, a previously unidentified bacterial strain that degrades QNC, strain D, was screened from paddy soil. The characteristics of strain D that relate to QNC degradation were investigated in detail. The results showed that strain D effectively degraded QNC. Two degradation products of QNC formed by strain D that have not been reported previously, i.e., 3-pyridylacetic acid ( m/z 138.0548) and 3-ethylpyridine ( m/z 108.0805), were identified using high-performance liquid chromatography–quadrupole time of flight mass spectrometry. Strain D has the capacity to degrade QNC in a QNC-polluted paddy.
    Type of Medium: Online Resource
    ISSN: 2165-0497
    URL: Article
    DOI: 10.1128/Spectrum.00398-21
    Language: English
    Publisher: American Society for Microbiology
    Publication Date: 2021
    detail.hit.zdb_id: 2807133-5
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  • 2
    Online Resource
    Online Resource
    Supporting Differentiated Services in Computers via Programmable Architecture for Resourcing-on-Demand (PARD)
    Association for Computing Machinery (ACM) ; 2015
    In:  ACM SIGPLAN Notices Vol. 50, No. 4 ( 2015-05-12), p. 131-143
    Details
    In: ACM SIGPLAN Notices, Association for Computing Machinery (ACM), Vol. 50, No. 4 ( 2015-05-12), p. 131-143
    Abstract: This paper presents PARD, a programmable architecture for resourcing-on-demand that provides a new programming interface to convey an application's high-level information like quality-of-service requirements to the hardware. PARD enables new functionalities like fully hardware-supported virtualization and differentiated services in computers. PARD is inspired by the observation that a computer is inherently a network in which hardware components communicate via packets (e.g., over the NoC or PCIe). We apply principles of software-defined networking to this intra-computer network and address three major challenges. First, to deal with the semantic gap between high-level applications and underlying hardware packets, PARD attaches a high-level semantic tag (e.g., a virtual machine or thread ID) to each memory-access, I/O, or interrupt packet. Second, to make hardware components more manageable, PARD implements programmable control planes that can be integrated into various shared resources (e.g., cache, DRAM, and I/O devices) and can differentially process packets according to tag-based rules. Third, to facilitate programming, PARD abstracts all control planes as a device file tree to provide a uniform programming interface via which users create and apply tag-based rules. Full-system simulation results show that by co-locating latencycritical memcached applications with other workloads PARD can improve a four-core computer's CPU utilization by up to a factor of four without significantly increasing tail latency. FPGA emulation based on a preliminary RTL implementation demonstrates that the cache control plane introduces no extra latency and that the memory control plane can reduce queueing delay for high-priority memory-access requests by up to a factor of 5.6.
    Type of Medium: Online Resource
    ISSN: 0362-1340 , 1558-1160
    URL: Article
    DOI: 10.1145/2775054.2694382
    Language: English
    Publisher: Association for Computing Machinery (ACM)
    Publication Date: 2015
    detail.hit.zdb_id: 2079194-X
    detail.hit.zdb_id: 282422-X
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  • 3
    Online Resource
    Online Resource
    Image_8.tif
    Frontiers Media SA ; 2022
    In:  Frontiers in Immunology Vol. 13 ( 2022-6-2)
    Details
    In: Frontiers in Immunology, Frontiers Media SA, Vol. 13 ( 2022-6-2)
    Abstract: Eosinophils are the main inflammatory effector cells that damage gastrointestinal tissue in eosinophilic gastrointestinal diseases (EGIDs). Activation of the OX40 pathway aggravates allergic diseases, such as asthma, but it is not clear whether OX40 is expressed in eosinophils to regulate inflammation in EGIDs. In this study, we assessed the expression and effect of OX40 on eosinophils in WT and Ox40 -/- eosinophilic gastroenteritis (EGE) mice. Methods Eosinophil infiltration, ovalbumin (OVA)-specific Ig production, OX40 expression and inflammatory factor levels in the intestine and bone marrow (BM) were investigated to evaluate inflammation. Results We confirmed that OVA-challenged mice produced high levels of Ox40, Mbp, Ccl11, Il5, Il4, Il13, and Il6 mRNA and a low level of Ifng mRNA in the intestine. Increased eosinophils were observed in intestinal and lymph tissues, accompanied by significantly upregulated OX40 and Type 2 cytokine production in eosinophils of EGE mice. Ox40 deficiency ameliorated OVA-induced inflammation, eosinophil infiltration, and cytokine production in the intestine. Consistently, Ox40 -/ - eosinophils exhibited decreased proliferation and proinflammatory function. The stimulation of the agonistic anti-OX40 antibody, OX86, promoted the effect of OX40 on eosinophils. The present study also showed that Ox40 deficiency dampened the Traf2/6-related NF-κB signaling pathway in eosinophils. Conclusions OX40 may play a critical role in the progress of OVA-induced EGE by promoting the maturation and function of eosinophils via the Traf2/6-related NF-κB signaling pathway.
    Type of Medium: Online Resource
    ISSN: 1664-3224
    URL: Article
    URL: Article
    URL: Article
    URL: Article
    URL: Article
    URL: Article
    URL: Article
    URL: Article
    URL: Article
    DOI: 10.3389/fimmu.2022.841141
    DOI: 10.3389/fimmu.2022.841141.s001
    DOI: 10.3389/fimmu.2022.841141.s002
    DOI: 10.3389/fimmu.2022.841141.s003
    DOI: 10.3389/fimmu.2022.841141.s004
    DOI: 10.3389/fimmu.2022.841141.s005
    DOI: 10.3389/fimmu.2022.841141.s006
    DOI: 10.3389/fimmu.2022.841141.s007
    DOI: 10.3389/fimmu.2022.841141.s008
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2606827-8
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  • 4
    Online Resource
    Online Resource
    Supporting Differentiated Services in Computers via Programmable Architecture for Resourcing-on-Demand (PARD)
    Association for Computing Machinery (ACM) ; 2015
    In:  ACM SIGARCH Computer Architecture News Vol. 43, No. 1 ( 2015-05-29), p. 131-143
    Details
    In: ACM SIGARCH Computer Architecture News, Association for Computing Machinery (ACM), Vol. 43, No. 1 ( 2015-05-29), p. 131-143
    Abstract: This paper presents PARD, a programmable architecture for resourcing-on-demand that provides a new programming interface to convey an application's high-level information like quality-of-service requirements to the hardware. PARD enables new functionalities like fully hardware-supported virtualization and differentiated services in computers. PARD is inspired by the observation that a computer is inherently a network in which hardware components communicate via packets (e.g., over the NoC or PCIe). We apply principles of software-defined networking to this intra-computer network and address three major challenges. First, to deal with the semantic gap between high-level applications and underlying hardware packets, PARD attaches a high-level semantic tag (e.g., a virtual machine or thread ID) to each memory-access, I/O, or interrupt packet. Second, to make hardware components more manageable, PARD implements programmable control planes that can be integrated into various shared resources (e.g., cache, DRAM, and I/O devices) and can differentially process packets according to tag-based rules. Third, to facilitate programming, PARD abstracts all control planes as a device file tree to provide a uniform programming interface via which users create and apply tag-based rules. Full-system simulation results show that by co-locating latencycritical memcached applications with other workloads PARD can improve a four-core computer's CPU utilization by up to a factor of four without significantly increasing tail latency. FPGA emulation based on a preliminary RTL implementation demonstrates that the cache control plane introduces no extra latency and that the memory control plane can reduce queueing delay for high-priority memory-access requests by up to a factor of 5.6.
    Type of Medium: Online Resource
    ISSN: 0163-5964
    URL: Article
    DOI: 10.1145/2786763.2694382
    RVK:
    SS 1985
    Language: English
    Publisher: Association for Computing Machinery (ACM)
    Publication Date: 2015
    detail.hit.zdb_id: 2088489-8
    detail.hit.zdb_id: 186012-4
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  • 5
    Online Resource
    Online Resource
    Quantitative Measurement and Analysis of Potassium in Soil Using Laser-Induced Breakdown Spectroscopy
    Shanghai Institute of Optics and Fine Mechanics ; 2014
    In:  Chinese Journal of Lasers Vol. 41, No. 5 ( 2014), p. 0515003-
    Details
    In: Chinese Journal of Lasers, Shanghai Institute of Optics and Fine Mechanics, Vol. 41, No. 5 ( 2014), p. 0515003-
    Type of Medium: Online Resource
    ISSN: 0258-7025
    Uniform Title: 土壤钾元素的激光诱导击穿光谱定量检测分析
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.3788/CJL/2014/41/5
    DOI: 10.3788/CJL
    DOI: 10.3788/CJL201441.0515003
    Language: English , Chinese
    Publisher: Shanghai Institute of Optics and Fine Mechanics
    Publication Date: 2014
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