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  • 1
    Online Resource
    Online Resource
    International Scientific Invention Journals ; 2018
    In:  International Journal of Innovative Research in Medical Science Vol. 3, No. 06 ( 2018-06-21)
    In: International Journal of Innovative Research in Medical Science, International Scientific Invention Journals, Vol. 3, No. 06 ( 2018-06-21)
    Abstract: Multinodular Goitre (MNG) is a common disorder and the incidence of hypothyroidism following thyroidectomy varies in different studies. Of the many factors which determine the post-operative thyroid hypofunction, the presence of an inflammatory infiltrate in the thyroid gland may have a significant role. The objective was to study the association of post-operative hypothyroidism and lymphocytic infiltration in the thyroid gland. This was a retrospective study of patients who underwent thyroidectomy. Detection of hypothyroidism was based on thyroid function test values. The lymphocytic infiltrate within the thyroid gland was graded as 0,1,2,3 & 4. Correlations between the grade of lymphocytic infiltration and the patient’s age, type of surgery and hypothyroid status was assessed. In our patients, 59 (57.2%) cases developed hypothyroidism post-operatively, of which 72.3% had a high lymphocytic grade. Out of the cases having a high lymphocytic infiltration who developed hypothyroidism, 63.8% were above 40 years of age. There was statistically significant correlation between the grade of lymphocytic infiltration and hypothyroid status post-operatively (p = 0.017). This suggests its role in the progressive development of post-operative hypothyroidism.
    Type of Medium: Online Resource
    ISSN: 2455-8737
    Language: Unknown
    Publisher: International Scientific Invention Journals
    Publication Date: 2018
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  • 2
    Online Resource
    Online Resource
    Innovare Academic Sciences Pvt Ltd ; 2021
    In:  Asian Journal of Pharmaceutical and Clinical Research ( 2021-03-07), p. 145-149
    In: Asian Journal of Pharmaceutical and Clinical Research, Innovare Academic Sciences Pvt Ltd, ( 2021-03-07), p. 145-149
    Abstract: Objective: Antibiotics are the only drug where use in one patient can impact the effectiveness in another, so antibiotic misuse adversely impacts the patients and society. Improving antibiotic use improves patient outcomes and saves money. Antibiotic resistance has been identified as a major threat by the WHO due to the lack of development of new antibiotics and the increasing infections caused by multidrug resistance pathogens became untreatable. Methods: A prospective observational study was conducted for a period of 6 months. Data were collected from prescriptions and inpatient record files at the surgery department of the tertiary care hospital. Patients above age of 18 years of either gender whose prescription containing the antibiotics and patients who are willing to participate in the study were included in the study. Microsoft Excel was used for recording and analyzing the data of recruited subjects. Results: During our study period, we have collected 100 cases as per inclusion criteria, in total collected 100 cases, 52% are male and 48% are female. The mean age and standard deviation of the study population were found to be 46.61±16.12. The most commonly prescribed classification before and after the surgery is cephalosporin’s that is 57%. Results show that in pre-surgery, almost 93% of prescriptions have chosen the drugs as per ASHP guidelines, whereas in post-surgery, 95% of drugs have selected the drug as per ASHP guidelines. Conclusion: Our study has observed that some of the prescriptions are irrationally prescribed so the pharmacist has to take the responsibility to improve the awareness regarding rational prescribing of antibiotics. The national wide monitoring of antibiotics use, national schemes to obtain rational use of antibiotics, reassessing the prescriptions, education to practitioners, and surveys on antibiotics should be implemented.
    Type of Medium: Online Resource
    ISSN: 2455-3891 , 0974-2441
    Language: Unknown
    Publisher: Innovare Academic Sciences Pvt Ltd
    Publication Date: 2021
    detail.hit.zdb_id: 2500247-8
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