GLORIA

GEOMAR Library Ocean Research Information Access

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
Material
Language
Years
Subjects(RVK)
  • 1
    In: Biomedicines, MDPI AG, Vol. 11, No. 8 ( 2023-08-03), p. 2187-
    Abstract: The transplantation of mesenchymal stem cell (MSC) sheets derived from human umbilical cords (hUCs) was investigated in this study as a potential application in treating myocardial infarction (MI). Two groups of hUC-MSC sheets were formed by populating LunaGelTM, which are 3D scaffolds of photo-crosslinkable gelatin-based hydrogel with two different cell densities. An MI model was created by ligating the left anterior descending coronary artery of healthy BALB/c mice. After two weeks, the cell sheets were applied directly to the MI area and the efficacy of the treatment was evaluated over the next two weeks by monitoring the mice’s weight, evaluating the left ventricle ejection fraction, and assessing the histology of the heart tissue at the end of the experiment. Higher cell density showed significantly greater efficiency in MI mice treatment in terms of weight gain and the recovery of ejection fraction. The heart tissue of the groups receiving cell sheets showed human-CD44-positive staining and reduced fibrosis and apoptosis. In conclusion, the hUC-MSC sheets ameliorated heart MI injury in mice and the efficacy of the cell sheets improved as the number of cells increased.
    Type of Medium: Online Resource
    ISSN: 2227-9059
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2720867-9
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 2
    In: Biomedicines, MDPI AG, Vol. 11, No. 4 ( 2023-04-12), p. 1158-
    Abstract: Stem cells have significant potential in regenerative medicines. However, a major issue with implanting stem cells in the regeneration of new tissue is the methods to implant them and cell viability and functions before and after implantation. Here we developed a simple yet effective method that used photo-crosslinkable gelatin-based hydrogel (LunaGelTM) as a scaffold for the encapsulation, expansion, and eventually, transplantation of human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) into mice subcutaneously. We demonstrated the proliferation and maintenance of the original expression of mesenchymal stem cell markers as well as the ability to differentiate into mesoderm-derived cells. The hydrogel was highly stable with no signs of degradation after 20 days in PBS. The hUC-MSCs remained viable after transplantation into mice’s subcutaneous pockets and migrated to integrate with the surrounding tissues. We showed a collagen-rich layer surrounding the transplanted cell-laden scaffold indicating the effects of growth factors secreted by the hUC-MSCs. A connective tissue layer was found between the implanted cell-laden scaffold and the collagen layer, and immunohistochemical staining results suggested that this tissue was derived from the MSCs which migrated from within the scaffold. The results, thus, also suggested a protective effect the scaffold has on the encapsulated cells from the antibodies and cytotoxic cells of the host immune system.
    Type of Medium: Online Resource
    ISSN: 2227-9059
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2720867-9
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 3
    In: Tạp chí Y học Dự phòng, Tap chi Y hoc du phong (Vietnam Journal of Preventive Medicine-VJPM), Vol. 32, No. 1 ( 2022-02-18), p. 365-371
    Abstract: Nghiên cứu mô tả cắt ngang được tiến hành trên 147 sinh viên cử nhân điều dưỡng chính quy năm 3, 4 trường Đại học Y Dược Hải Phòng năm 2021. Với lý do các tai biến và tỷ lệ tử vong do phản vệ có thể giảm khi điều dưỡng nắm được kiến thức, thái độ để thực hiện đúng cách phòng chống và chăm sóc người bệnh phản vệ, chúng tôi thực hiện nghiên cứu nhằm mô tả thực trạng kiến thức, thái độ về dự phòng và xử trí phản vệ của sinh viên điều dưỡng chính quy sau khi thực hành lâm sàng tại bệnh viện. Kết quả nghiên cứu cho thấy trên 90% sinh viên có kiến thức về khái niệm, nguyên nhân và triệu chứng của phản vệ; cách khai thác tiền sử dị ứng; thành phần hộp chống sốc; đường dùng adrenalin thích hợp. Tuy nhiên 15% sinh viên nhận thức không đúng khi coi các chế phẩm máu không nằm trong nguyên nhân phản vệ, trên 60% trả lời sai về các biểu hiện tuần hoàn, hô hấp của phản vệ, 23,8% không trả lời đúng về thời gian theo dõi huyết áp. Sinh viên có thái độ tốt về cách dự phòng và xử trí phản vệ nhưng có 55,8% sinh viên cho rằng cần thiết làm test loại kháng sinh khi người bệnh đã bị dị ứng loại kháng sinh đó.
    Type of Medium: Online Resource
    ISSN: 0868-2836
    Language: Unknown
    Publisher: Tap chi Y hoc du phong (Vietnam Journal of Preventive Medicine-VJPM)
    Publication Date: 2022
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 4
    Online Resource
    Online Resource
    Vietnam National University of Forestry ; 2022
    In:  Tạp chí Khoa học và Công nghệ Lâm nghiệp , No. 2 ( 2022), p. 155-164
    In: Tạp chí Khoa học và Công nghệ Lâm nghiệp, Vietnam National University of Forestry, , No. 2 ( 2022), p. 155-164
    Abstract: Thông qua việc sử dụng phương pháp 4 phương pháp nghiên cứu: chọn điểm nghiên cứu, thu thập số liệu thứ cấp, thu thập số liệu sơ cấp và phân tích, thống kê và xử lý số liệu nghiên cứu đã đánh giá được thực trạng công tác đăng ký và cấp giấy chứng nhận quyền sử dụng đất trong khu gia đình quân nhân tại thành phố Biên Hòa, tỉnh Đồng Nai. Cụ thể trong giai đoạn 2016-2020 tại thành phố Biên Hòa có 20 khu gia đình đã và đang được kê khai đăng ký và cấp giấy chứng nhận quyền sử dụng đất, chiếm tỷ lệ 43,47% với có 9.253 hộ gia đình tương ứng 9.253 thửa đất (96,68%); còn lại 318 hộ gia đình, cá nhân chưa được kê khai đăng ký, chiếm tỷ lệ 3,32%. Ngoài ra, đã cấp được 4.133 giấy chứng nhận, đạt tỷ lệ 52,84%; còn lại 3.689 giấy chứng nhận (47,16%) chưa được cấp. Nguyên nhân chủ yếu tập trung vào vấn đề xác minh nguồn gốc đất, không phù hợp với quy hoạch được phê duyệt, việc đóng tiền sử dụng đất quá cao người dân chưa đủ điều kiện hoàn thành. Kết quả đánh giá của 2 nhóm hộ về công tác cấp giấy chứng nhận quyền sử dụng đất thông qua 6 chỉ tiêu có sự khác biệt giữa 2 nhóm hộ cụ thể là vấn đề thời gian hoàn thiện hồ sơ và phí lệ phí là một trong những nguyên nhân mà các hộ chưa được cấp giấy chứng nhận. Do đó, để nâng cao hiệu quả và đẩy nhanh tiến độ cấp, phát giấy chứng nhận quyền sử dụng đất cho khu gia đình quân nhân tại thành phố Biên Hòa cần phải có sự phối kết hợp của các cơ quan ban ngành và các giải pháp cụ thể: Giải pháp về thủ tục hành chính, giải pháp về quy hoạch, giải pháp về hoàn thiện hồ sơ, giải pháp về tài chính, giải pháp về khoa học, cộng nghệ và giải pháp về nguồn lực.
    Type of Medium: Online Resource
    ISSN: 1859-3828
    Language: Unknown
    Publisher: Vietnam National University of Forestry
    Publication Date: 2022
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 5
    Online Resource
    Online Resource
    Hanoi Medical University ; 2022
    In:  Tạp chí Nghiên cứu Y học Vol. 161, No. 12E11 ( 2022-12-28), p. 163-172
    In: Tạp chí Nghiên cứu Y học, Hanoi Medical University, Vol. 161, No. 12E11 ( 2022-12-28), p. 163-172
    Abstract: This study aimed to describe the diagnostic performance of lung ultrasound (LUS) in detecting and semi-quantifying pneumothorax (PTX), using computed tomography (CT) as the reference standard. The study included 150 patients who underwent CT-guided transthoracic biopsy (TTB) for lung lesions. Within 30 minutes, two radiologists blinded to the participant’s prior information performed LUS in asymptomatic patients. The results showed that PTX was present on CT in 49/150 (32.3%) cases. LUS was positive in 40/150 (26.7%) patients, with a substantial agreement between the two radiologists (Cohen κ statistics = 0.8). The sensitivity and specificity of LUS were 100% (95%CI 97.6% to 100%) and 91.8% (95%CI 87.4% to 96.2%), respectively. Moreover, the positive and negative predictive values were 87.5% (95%CI 82.2% to 92.8%) and 96.4% (95%CI 92.4% to 98.9%), respectively. In the semi-quantification of PTX by LUS, the location of lung point was described in 36/49 (73.5%) patients. The sensitivity and specificity of this sign were 87.5% (95%CI 82.2% to 92.8%) and 96.4% (95%CI 92.4% to 98.9%), respectively. The positive and negative predictive values were 87.5% (95%CI 82.2% to 92.8%) and 96.4% (95%CI 92.4% to 98.9%), respectively. In conclusion, LUS is a susceptible and specific diagnostic method for diagnosing and semi-quantifying PTX.
    Type of Medium: Online Resource
    ISSN: 2354-080X , 2354-080X
    URL: Issue
    Language: Unknown
    Publisher: Hanoi Medical University
    Publication Date: 2022
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 6
    In: Critical Care, Springer Science and Business Media LLC, Vol. 27, No. 1 ( 2023-07-01)
    Abstract: Interpreting point-of-care lung ultrasound (LUS) images from intensive care unit (ICU) patients can be challenging, especially in low- and middle- income countries (LMICs) where there is limited training available. Despite recent advances in the use of Artificial Intelligence (AI) to automate many ultrasound imaging analysis tasks, no AI-enabled LUS solutions have been proven to be clinically useful in ICUs, and specifically in LMICs. Therefore, we developed an AI solution that assists LUS practitioners and assessed its usefulness in  a low resource ICU. Methods This was a three-phase prospective study. In the first phase, the performance of four different clinical user groups in interpreting LUS clips was assessed. In the second phase, the performance of 57 non-expert clinicians with and without the aid of a bespoke AI tool for LUS interpretation was assessed in retrospective offline clips. In the third phase, we conducted a prospective study in the ICU where 14 clinicians were asked to carry out LUS examinations in 7 patients with and without our AI tool and we interviewed the clinicians regarding the usability of the AI tool. Results The average accuracy of beginners’ LUS interpretation was 68.7% [95% CI 66.8–70.7%] compared to 72.2% [95% CI 70.0–75.6%] in intermediate, and 73.4% [95% CI 62.2–87.8%] in advanced users. Experts had an average accuracy of 95.0% [95% CI 88.2–100.0%] , which was significantly better than beginners, intermediate and advanced users ( p   〈  0.001). When supported by our AI tool for interpreting retrospectively acquired clips, the non-expert clinicians improved their performance from an average of 68.9% [95% CI 65.6–73.9%] to 82.9% [95% CI 79.1–86.7%] , ( p   〈  0.001). In prospective real-time testing, non-expert clinicians improved their baseline performance from 68.1% [95% CI 57.9–78.2%] to 93.4% [95% CI 89.0–97.8%] , ( p   〈  0.001) when using our AI tool. The time-to-interpret clips improved from a median of 12.1 s (IQR 8.5–20.6) to 5.0 s (IQR 3.5–8.8), ( p   〈  0.001) and clinicians’ median confidence level improved from 3 out of 4 to 4 out of 4 when using our AI tool. Conclusions AI-assisted LUS can help non-expert clinicians in an LMIC ICU improve their performance in interpreting LUS features more accurately, more quickly and more confidently.
    Type of Medium: Online Resource
    ISSN: 1364-8535
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 2051256-9
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 7
    In: Tạp chí Y học Dự phòng, Tap chi Y hoc du phong (Vietnam Journal of Preventive Medicine-VJPM), Vol. 30, No. 9 ( 2021-04-25), p. 51-58
    Abstract: Health literacy refers to the degree to which people can access and understand health information, as well as communicate their health needs to service providers. The scale has been standardized and divided into 3 groups: Health care, prevention of disease, health promotion. Children under 3 years have immature immunological system, which can affect their development in the future. However, the health management, diseases treatment, and diseases prevention of children younger than 3 years of age depend signifcantly on the health literacy of their mothers. This study aims to describe the health literacy of mothers who have children under 3 years and some factors affecting their health literacy. Data were collected on 389 mothers of children younger than 3 years who take their children to the vaccination clinics at Hanoi Medical University and latent analysis was conducted to identify class of health literacy within the sample. Three health literacy classes were identifed. The lowest mean health literacy index was within the disease prevention dimension, where the largest number of respondents showed limited health literacy. Three distinct health literacy level were identifed and termed low (n = 35.9%), moderate (n = 243, 62.5%) and high health literacy (n = 111, 28.5%). We found that higher scores of Health Literacy Scores (HLS) closely correlated with higher educational levels, the job of mothers, the age of children and the frequency of searching for health information using the internet. There were signifcant better overall scores in HLS among parents with higher education levels (university degree or higher with more than under high school graduated).
    Type of Medium: Online Resource
    ISSN: 0868-2836
    Language: Unknown
    Publisher: Tap chi Y hoc du phong (Vietnam Journal of Preventive Medicine-VJPM)
    Publication Date: 2021
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 8
    In: Tạp chí Y học Dự phòng, Tap chi Y hoc du phong (Vietnam Journal of Preventive Medicine-VJPM), Vol. 31, No. 4 ( 2021-06-18), p. 107-117
    Abstract: E-cigarettes (e-cigarettes) have been using social media as an informative platform to promote e-cigarettes for their users. The most popular social media in Vietnam were YouTube and Facebook. The information and knowledge could affect e-cigarette user’s belief and the way they make a decision. Despite this, there is a gap in our knowledge of policy maker’s in user’s perceptions about how they feel with promotion on social media platform in Vietnam. This study aimed to describe the promotion of e-cigarettes by providers on some social networks and to describe electronic cigarette users’ feedback about videos/posts of providers on some social networks in Vietnam in 2019. Searches in major electronic databases, including Facebook and YouTube, were conducted using the following search terms: “electronic cigarette,” “electronic vaporizer,” “electronic pod,”. The video/post was selected if they’re from providers and include advertising content on the social media platform during 2019. Of the 104 e-cigarette related videos/posts retrieved, there were 27% on Facebook and 28% on YouTube. The three most common advertising contents were beneft of using e-cigarette, negative health consequences and entertainment effects.
    Type of Medium: Online Resource
    ISSN: 0868-2836
    Language: Unknown
    Publisher: Tap chi Y hoc du phong (Vietnam Journal of Preventive Medicine-VJPM)
    Publication Date: 2021
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 9
    In: Processes, MDPI AG, Vol. 8, No. 2 ( 2020-02-04), p. 173-
    Abstract: Callicarpa candicans (Burm. f.) Hochr. (Callicarpa cana L.) is a medicinal plant that is distributed mainly in the tropics and subtropics of Asia and finds a wide range of uses in traditional medicine. In this study, we attempted and optimized the microwave-assisted hydro-distillation (MAHD) process to obtain essential oil from the leaves of C. candicans. In addition, the obtained oil was analyzed for volatile composition by gas chromatography–mass spectrometry (GC-MS) and assayed for bioactivity against several bacteria and cancer cell lines. To optimize the extraction process, response surface methodology (RSM) in combination with central composite design (CCD) was adopted. Experimental design and optimization were carried out with respect to three experimental factors including the ratio of water to raw material, extraction time, and microwave power. The optimal extraction conditions were obtained as follows: water to raw material ratio of 6/1 (v/w), extraction time 42 min, and microwave power 440 W. Composition determination of the obtained C. candicans essential oil indicated the presence of predominant components including caryophyllene 〈 b- 〉 (10.45%), cadinene 〈 d- 〉 (10.28%), gurjunene 〈 a- 〉 (8.95%), muurolene 〈 g- 〉 (8.92%), selinene 〈 a- 〉 (7.06%), selinene 〈 b- 〉 (5.59%), and copaene 〈 a- 〉 (5.40%). In comparison with the essential oils obtained via traditional hydro-distillation method, the essential oil extracted by MAHD exhibited superior anti-proliferative activity on all tested cancer cell lines. Current results imply that the MAHD is capable of recovering biologically-active natural products of greater quantity than that recovered by the conventional distillation.
    Type of Medium: Online Resource
    ISSN: 2227-9717
    Language: English
    Publisher: MDPI AG
    Publication Date: 2020
    detail.hit.zdb_id: 2720994-5
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
  • 10
    In: RSC Advances, Royal Society of Chemistry (RSC), Vol. 10, No. 73 ( 2020), p. 45199-45206
    Type of Medium: Online Resource
    ISSN: 2046-2069
    Language: English
    Publisher: Royal Society of Chemistry (RSC)
    Publication Date: 2020
    detail.hit.zdb_id: 2623224-8
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...