In:
Angewandte Chemie International Edition, Wiley, Vol. 54, No. 18 ( 2015-04-27), p. 5478-5482
Abstract:
A rhodium(III)‐catalyzed cross‐coupling of benzyl thioethers and aryl carboxylic acids through the two directing groups is reported. Useful structures with diverse substituents were efficiently synthesized in one step with the cleavage of four bonds (CH, CS, OH) and the formation of two bonds (CC, CO). The formed structure is the privileged core in natural products and bioactive molecules. This work highlights the power of using two different directing groups to enhance the selectivity of a double CH activation, the first of such examples in cross‐oxidative coupling.
Type of Medium:
Online Resource
ISSN:
1433-7851
,
1521-3773
DOI:
10.1002/anie.201500486
Language:
English
Publisher:
Wiley
Publication Date:
2015
detail.hit.zdb_id:
2011836-3
detail.hit.zdb_id:
123227-7
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