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  • 1
    Online Resource
    Online Resource
    American Society for Horticultural Science ; 2006
    In:  HortScience Vol. 41, No. 3 ( 2006-06), p. 556-560
    In: HortScience, American Society for Horticultural Science, Vol. 41, No. 3 ( 2006-06), p. 556-560
    Abstract: AVRDC–The World Vegetable Center was established in 1971 as a not-for-profit international agricultural research institute whose mission is to reduce malnutrition and poverty among the poor through vegetable research and development. Over the past 30 years, AVRDC has developed a vast array of international public goods. The Center plays an essential role in bringing international and interdisciplinary teams together to develop technologies, empower farmers, and address major vegetable-related issues in the developing world. In its unique role, AVRDC functions as a catalyst to 1) build international and interdisciplinary coalitions that engage in vegetable and nutrition issues; 2) generate and disseminate improved germplasm and technologies that address economic and nutritional needs of the poor; 3) collect, characterize, and conserve vegetable germplasm resources for worldwide use; and 4) provide globally accessible, user-friendly, science-based, appropriate technology. In enhancing and promoting vegetable production and consumption in developing world, AVRDC's research programs contribute to increased productivity of the vegetable sector, equity in economic development in favor of rural and urban poor, healthy and more diversified diets for low-income families, environmentally friendly and safe production of vegetables, and improved sustainability of cropping systems. Recent achievements at AVRDC that greatly impact tropical horticulture in the developing world include virus-resistant tomatoes raising farmers income, hybrid sweet pepper breaking the yield barrier in the tropics, flood-resistant chili peppers opening new market opportunities, broccoli varieties for monsoon season, pesticide-free eggplant and leafy vegetable production systems and fertilizer systems that protect the environment. Beyond vegetable crops, AVRDC is playing an important role in expanding and promoting research and development efforts for high value horticultural crops, including fruit, ornamentals, and medicinal plants through its new Global Horticulture Initiative. AVRDC believes that horticulture crop production provides jobs and is an engine for economic growth. The important role AVRDC–The World Vegetable Center plays in developing and promoting tropical horticultural crops is discussed in this paper.
    Type of Medium: Online Resource
    ISSN: 0018-5345 , 2327-9834
    Language: Unknown
    Publisher: American Society for Horticultural Science
    Publication Date: 2006
    detail.hit.zdb_id: 2040198-X
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  • 2
    Online Resource
    Online Resource
    Informa UK Limited ; 1988
    In:  Arid Soil Research and Rehabilitation Vol. 2, No. 3 ( 1988-01), p. 145-155
    In: Arid Soil Research and Rehabilitation, Informa UK Limited, Vol. 2, No. 3 ( 1988-01), p. 145-155
    Type of Medium: Online Resource
    ISSN: 0890-3069
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 1988
    detail.hit.zdb_id: 1490766-5
    detail.hit.zdb_id: 2068822-2
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  • 3
    In: The Journal of Immunology, The American Association of Immunologists, Vol. 200, No. 1_Supplement ( 2018-05-01), p. 108.8-108.8
    Abstract: Macrophage phagocytosis and cytokine production are sensitive to the surrounding matrix and thereby mediate host defense and lung tissue injury. The consequences and mechanism of this matrix sensitivity are unknown. We have determined that the mechanosensitive channel, TRPV4, responds to extracellular matrix biophysical properties and thereby modulates the macrophage response to pathogens. We undertook this study to determine the in vivo consequences and the intracellular signaling pathway by which TRPV4 modulates macrophage responses. In order to evaluate the role of TRPV4 in chronic pneumonia/lung injury, WT and TRPV4 KO mice were administered agarose bead embedded-Pseudomonas aeruginosa. Loss of TRPV4 led to decreased phagocytosis by macrophages (6-fold), and increased lung injury as measured by inflammatory cell infiltration (≥ 80 ± 3%), vascular permeability (total protein ≥ 63 ± 6%), and cytokine secretion (IL-1β ≥ 71 ± 4%). In vivo, lung alveolar macrophages predominantly expressed TRPV4 and were the key phagocytic cell, as assessed by FACS and immunofluorescence. Known LPS signaling pathways were investigated in vitro. Loss of TRPV4 abrogates LPS-induced p38 activation and phagocytosis of E. coli particles. Additionally, loss of TRPV4 increased basal pro-/active IL-1β expression (2-fold), thereby enhancing IL-1β secretion independent of caspase 1 cleavage and blockade. These findings demonstrate that TRPV4 is important for bacterial clearance, lung injury and cytokine production in macrophages. TRPV4 mediates these effects through p38 and through upregulation of IL-1β protein expression in an inflammasome-independent manner. The results implicate macrophage TRPV4 as a key component of the host defense.
    Type of Medium: Online Resource
    ISSN: 0022-1767 , 1550-6606
    RVK:
    RVK:
    Language: English
    Publisher: The American Association of Immunologists
    Publication Date: 2018
    detail.hit.zdb_id: 1475085-5
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  • 4
    In: Psychiatric Annals, SLACK, Inc., Vol. 39, No. 8 ( 2009-08)
    Abstract: 〈 p 〉 An increasing number of troops have returned from U.S. military Operation Iraqi Freedom and Operation Enduring Freedom (OIF/OEF) presenting with traumatic brain injury (TBI) and posttraumatic stress disorder (PTSD). In a recent survey, 19% of OIF/OEF veterans reported a probable TBI, and 14% met screening criteria for PTSD. TBI and PTSD have been referred to as the “signature wounds” of OIF/OEF. 〈 /p 〉 〈 h4 〉 ABOUT THE AUTHORS 〈 /H4 〉 〈 p 〉 Thomas A. Campbell, PhD, is with the Mental Health Service, Hunter Holmes McGuire Department of Veterans Affairs Medical Center, Richmond, Virginia. Lonnie A. Nelson, PhD, is with the Defense and Veterans Brain Injury Center, Primary TBI Operational Component of the Defense Centers of Excellence in TBI and Psychological Health, Rosslyn, Virginia. Robin Lumpkin, BA, and Cortney L. McCormick, MA, are with the Mental Illness Research, Education and Clinical Center (MIRECC), VISN6, Durham, North Carolina. Ruth E. Yoash-Gantz, PsyD, is with the MIRECC; the Hefner Veterans Affairs Medical Center, Salisbury, North Carolina; and the Department of Psychiatry and Behavioral Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina. Treven C. Pickett, PsyD, is with the Mental Health Service, Hunter Holmes McGuire Department of Veterans Affairs Medical Center; MIRECC; and the Department of Physical Medicine and Rehabilitation, Virginia Commonwealth University School of Medicine, Richmond. 〈 /p 〉 〈 p 〉 Address correspondence to: Thomas A. Campbell, PhD, McGuire VA Medical Center, Psychology Section (116B), 1201 Broad Rock Blvd., Richmond, VA 23249; or e-mail 〈 A HREF="mailto:Thomas.Campbell4@va.gov" 〉 Thomas.Campbell4@va.gov 〈 /A 〉 . 〈 /p 〉 〈 p 〉 Dr. Campbell; Dr. Nelson; Ms. Lumpkin; Dr. Yoash-Gantz; Dr. Pickett; and Ms. McCormick have disclosed no relevant financial relationships. 〈 /p 〉 〈 p 〉 doi: 10.3928/00485713-20090728-01 〈 /p 〉 〈 H4 〉 EDUCATIONAL OBJECTIVES 〈 /H4 〉 〈 OL 〉 〈 P 〉 〈 LI 〉 Evaluate measures of processing speed and executive functioning in OEF/OIF combat veterans with posttraumatic stress disorder (PTSD), traumatic brain injury (TBI), and comorbid TBI/PTSD. 〈 /P 〉 〈 /LI 〉 〈 P 〉 〈 LI 〉 Assess the role that comorbid TBI/PTSD may play in the speed of verbal processing. 〈 /P 〉 〈 /LI 〉 〈 P 〉 〈 LI 〉 Justify potential reasons slowed speed of verbal processing may impact therapies for PTSD. 〈 /P 〉 〈 /LI 〉 〈 /OL 〉
    Type of Medium: Online Resource
    ISSN: 0048-5713 , 1938-2456
    Language: English
    Publisher: SLACK, Inc.
    Publication Date: 2009
    SSG: 5,21
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  • 5
    Online Resource
    Online Resource
    Elsevier BV ; 2011
    In:  Cryobiology Vol. 63, No. 3 ( 2011-12), p. 313-
    In: Cryobiology, Elsevier BV, Vol. 63, No. 3 ( 2011-12), p. 313-
    Type of Medium: Online Resource
    ISSN: 0011-2240
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2011
    detail.hit.zdb_id: 1463192-1
    detail.hit.zdb_id: 80098-3
    SSG: 12
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  • 6
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 1985
    In:  Proceedings of the Royal Society of Edinburgh. Section B. Biological Sciences Vol. 86 ( 1985), p. 161-167
    In: Proceedings of the Royal Society of Edinburgh. Section B. Biological Sciences, Cambridge University Press (CUP), Vol. 86 ( 1985), p. 161-167
    Abstract: The aquatic fern Azolla has a symbiotic relationship with an N 2 -fixing cyanobacterium. Fanners in China and Vietnam have used Azolla for centuries as a green manure for rice and as fodder for pigs, ducks and fish. Chinese researchers have been studying Azolla since the early 1950's but many of their achievements are unknown outside China because of language and other communication problems. This article reviews current Chinese Azolla research and focuses on the impact of newly introduced Azolla species in the areas of field application, use of spores, and isolation of the N 2 -fixing symbiont.
    Type of Medium: Online Resource
    ISSN: 0269-7270 , 2053-5910
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 1985
    detail.hit.zdb_id: 209231-1
    SSG: 12
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  • 7
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 1989
    In:  Euphytica Vol. 43, No. 3 ( 1989-10), p. 223-232
    In: Euphytica, Springer Science and Business Media LLC, Vol. 43, No. 3 ( 1989-10), p. 223-232
    Type of Medium: Online Resource
    ISSN: 0014-2336 , 1573-5060
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 1989
    detail.hit.zdb_id: 2012322-X
    SSG: 12
    SSG: 21
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  • 8
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 1989
    In:  Euphytica Vol. 42, No. 1-2 ( 1989-06), p. 163-170
    In: Euphytica, Springer Science and Business Media LLC, Vol. 42, No. 1-2 ( 1989-06), p. 163-170
    Type of Medium: Online Resource
    ISSN: 0014-2336 , 1573-5060
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 1989
    detail.hit.zdb_id: 2012322-X
    SSG: 12
    SSG: 21
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  • 9
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 1980
    In:  Economic Botany Vol. 34, No. 2 ( 1980-4), p. 111-153
    In: Economic Botany, Springer Science and Business Media LLC, Vol. 34, No. 2 ( 1980-4), p. 111-153
    Type of Medium: Online Resource
    ISSN: 0013-0001 , 1874-9364
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 1980
    detail.hit.zdb_id: 2158805-3
    SSG: 12
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  • 10
    Online Resource
    Online Resource
    Elsevier BV ; 2005
    In:  SSRN Electronic Journal
    In: SSRN Electronic Journal, Elsevier BV
    Type of Medium: Online Resource
    ISSN: 1556-5068
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2005
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