In:
Journal of Medical Microbiology, Microbiology Society, Vol. 55, No. 1 ( 2006-01-01), p. 115-118
Kurzfassung:
Peritoneal dialysis-associated peritonitis due to fungi of the class Zygomycetes occurs very rarely. A case of fungal continuous ambulatory peritoneal dialysis peritonitis due to Cunninghamella bertholletiae is reported in a 39-year-old Aboriginal woman with end-stage renal failure and diabetes mellitus. This isolate was found to be resistant in vitro to amphotericin B, 5-fluorocytosine, fluconazole, itraconazole, ketoconazole and voriconazole. However, this patient was successfully treated with voriconazole and removal of the Tenckhoff dialysis catheter. Zygomycoses are an emerging threat among immunocompromised patients, including those with chronic renal failure. Zygomycosis due to C. bertholletiae is frequently fatal and is often non-responsive to systemic antifungal therapy. This is believed to be the first reported case of C. bertholletiae causing peritonitis in humans and one of the minority of cases involving this organism with a successful outcome.
Materialart:
Online-Ressource
ISSN:
0022-2615
,
1473-5644
DOI:
10.1099/jmm.0.46202-0
Sprache:
Englisch
Verlag:
Microbiology Society
Publikationsdatum:
2006
ZDB Id:
2083944-3
SSG:
12
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