In:
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, Vol. 47, No. 12 ( 2003-12), p. 3825-3830
Abstract:
The
susceptibilities of 430 Campylobacter jejuni strains and 79 C. coli strains to six antimicrobial agents were tested and
analyzed. The two sets of strains originated from retail market chicken and turkey samples and from humans, respectively, in Berlin, Germany.
Two groups of isolates, one dating from 1991 and the other dating from 2001-2002, were tested. Of the Campylobacter sp. isolates
recovered from humans in 2001-2002, 45.1% were resistant to ciprofloxacin, 37.8% were resistant to tetracycline,
12.8% were resistant to ampicillin, and 50.0% were resistant to trimethoprim-sulfamethoxazole. All isolates were
susceptible to gentamicin, while the overall rate of resistance to erythromycin was 6.1%. During the 10 years between the two
sampling times, the rates of resistance to ciprofloxacin ( P 〈 0.001), ampicillin ( P = 0.035), and
tetracycline ( P = 0.01) increased significantly among
strains isolated from humans. Furthermore, among human C. coli strains the rate of resistance to erythromycin rose from 7.1% in
1991 to 29.4% in 2001-2002. In comparison, Campylobacter sp. isolates from poultry already had high rates
of resistance in 1991. Different rates of resistance to tetracycline among isolates from chickens and turkeys suggested the development of
resistance during antimicrobial treatment in food animals. Thus, discrepancies in the antimicrobial resistance rates among Campylobacter isolates originating from poultry and humans
support the hypothesis that at least some of the resistant Campylobacter strains causing infection in humans come from
sources other than poultry products.
Type of Medium:
Online Resource
ISSN:
0066-4804
,
1098-6596
DOI:
10.1128/AAC.47.12.3825-3830.2003
Language:
English
Publisher:
American Society for Microbiology
Publication Date:
2003
detail.hit.zdb_id:
1496156-8
SSG:
12
SSG:
15,3
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