In:
Chemistry & Biodiversity, Wiley, Vol. 20, No. 1 ( 2023-01)
Abstract:
Four new xanthone glucosides, 3‐hydroxy‐2‐methoxyxanthone‐4‐O‐ β ‐D‐glucopyranoside ( 1 ), 4,8‐dihydroxy‐2‐methoxyxanthone‐3‐O‐ β ‐D‐glucopyranoside ( 2 ), 2‐methoxyxanthone‐5‐O‐ β ‐D‐glucopyranoside ( 3 ), 4‐hydroxy‐2‐methoxyxanthone‐3‐O‐ β ‐D‐glucopyranoside ( 4 ), a new phenolic acid, 4,4 ′ ‐dihydroxy‐3,3 ′ ‐imino‐di‐benzoic acid monomethyl ester ( 5 ), and a new isoquinoline, methyl 6‐hydroxy‐1‐oxo‐1,2,3,4‐tetrahydroisoquinoline‐4‐carboxylate ( 6 ) were isolated from the fruit of Hypericum patulum . The structural elucidation of the isolated compounds was primarily based on HR‐ESI‐MS, UV, IR, 1D and 2D NMR. All compounds were evaluated for their inhibitory effect against LPS‐induced NO production in RAW 264.7 cells. Compound 2 , 3 exhibited moderate inhibitory activity against NO production.
Type of Medium:
Online Resource
ISSN:
1612-1872
,
1612-1880
DOI:
10.1002/cbdv.202200900
Language:
English
Publisher:
Wiley
Publication Date:
2023
detail.hit.zdb_id:
2139001-0
SSG:
12
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