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  • 1
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    Online Resource
    Integration of independent component analysis with near infrared spectroscopy for evaluation of rice freshness
    Elsevier BV ; 2014
    In:  Journal of Cereal Science Vol. 60, No. 1 ( 2014-07), p. 238-242
    Details
    In: Journal of Cereal Science, Elsevier BV, Vol. 60, No. 1 ( 2014-07), p. 238-242
    Type of Medium: Online Resource
    ISSN: 0733-5210
    URL: Article
    DOI: 10.1016/j.jcs.2014.03.005
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2014
    detail.hit.zdb_id: 408468-8
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  • 2
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    Identification of Bioactive Components from Ruellia tuberosa L. on Improving Glucose Uptake in TNF-α-Induced Insulin-Resistant Mouse FL83B Hepatocytes
    Wiley ; 2020
    In:  Evidence-Based Complementary and Alternative Medicine Vol. 2020 ( 2020-12-1), p. 1-7
    Details
    In: Evidence-Based Complementary and Alternative Medicine, Wiley, Vol. 2020 ( 2020-12-1), p. 1-7
    Abstract: Ruellia tuberosa L. (RTL) has been used as a folk medicine to cure diabetes in Asia. RTL was previously reported to alleviate hyperglycemia, insulin resistance (IR), abnormal hepatic detoxification, and liver steatosis. However, the potential bioactive compounds of RTL have still not been identified. The aim of this study was to investigate the bioactive compounds in RTL ethyl acetate (EA) fractions by using a glucose uptake assay in TNF-α-treated mouse FL83B hepatocytes to discover a mechanism by which to improve IR. The bioactive compounds were identified by the high-performance liquid chromatography (HPLC) assay. Using the Sephadex LH20 gel packing chromatography column, the EAF5 fraction was isolated from RTL and significantly increased glucose uptake in TNF-α-treated FL83B cells. Moreover, the MCI gel packing chromatography column separated EAF5 into five subfractions and had no significant cytotoxic effect in FL83B cells when treated at the concentration of 25 μg/ml. Among the subfractions, EAF5-5 markedly enhanced glucose uptake in TNF-α-treated FL83B cells. The possible bioactive compounds of the EAF5-5 fraction that were identified by the HPLC assay include syringic acid, p-coumaric acid, and cirsimaritin. The bioactive compound with the best effect of increasing glucose uptake was p-coumaric acid, but its effect alone was not as good as the combined effect of all three compounds of the EAF5-5 fraction. Thus, we speculate that the antidiabetic effect of RTL may be the result of multiple active ingredients.
    Type of Medium: Online Resource
    ISSN: 1741-4288 , 1741-427X
    URL: Article
    DOI: 10.1155/2020/6644253
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2171158-6
    detail.hit.zdb_id: 2148302-4
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  • 3
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    Quantification of bioactive gentiopicroside in the medicinal plant Gentiana scabra Bunge using near infrared spectroscopy
    The Journal of Food and Drug Analysis (JFDA), Food and Drug Administration, Taiwan (TFDA) ; 2013
    In:  Journal of Food and Drug Analysis Vol. 21, No. 3 ( 2013-09), p. 317-324
    Details
    In: Journal of Food and Drug Analysis, The Journal of Food and Drug Analysis (JFDA), Food and Drug Administration, Taiwan (TFDA), Vol. 21, No. 3 ( 2013-09), p. 317-324
    Type of Medium: Online Resource
    ISSN: 1021-9498
    URL: Article
    DOI: 10.1016/j.jfda.2013.07.011
    Language: English
    Publisher: The Journal of Food and Drug Analysis (JFDA), Food and Drug Administration, Taiwan (TFDA)
    Publication Date: 2013
    detail.hit.zdb_id: 1292535-4
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  • 4
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    Effects of α-Lipoic Acid on Phagocytosis of Oligomeric Beta-Amyloid1–42 in BV-2 Mouse Microglial Cells
    Frontiers Media SA ; 2022
    In:  Frontiers in Aging Neuroscience Vol. 13 ( 2022-1-12)
    Details
    In: Frontiers in Aging Neuroscience, Frontiers Media SA, Vol. 13 ( 2022-1-12)
    Abstract: Background and objectives: This study aimed to investigate the enhancing effect of vitamin-like alpha-lipoic acid (ALA) on phagocytosis of oligomeric beta-amyloid (oAβ) 1–42 in BV-2 mouse microglial cells. Methods: An in vitro model was established to investigate phagocytosis of oAβ 1–42 in BV-2 cells. Transmission electron microscopy images indicated that the morphology of prepared oAβ 1–42 was spherical particles. BV-2 cells treated with ALA were incubated with 5(6)-carboxyfluorescein-labeled oAβ 1–42 (FAM-oAβ 1–42 ) for 24 h, followed by flow cytometer analysis, western blotting, real-time quantitative PCR, and immunocytochemistry (ICC) analysis to assess the in vitro phagocytosis ability of oAβ 1–42 . Results: Alpha-lipoic acid significantly increased messenger RNA (mRNA) expression of the CD36 receptor in BV-2 cells. ICC analysis showed that ALA significantly elevated CD36 protein expression in BV-2 cells both with and without oAβ 1–42 treatment. Results from the flow cytometry analysis indicated that the CD36 receptor inhibitor significantly attenuated ALA-promoted phagocytosis of FAM-oAβ 1–42 in BV-2 cells. Moreover, ICC analysis revealed that ALA caused the translocation of peroxisome proliferator-activated receptor-γ (PPAR-γ), which is known to regulate the expression of CD36 mRNA in BV-2 cells. ALA also elevated both the mRNA and protein expression of cyclooxygenase-2 (COX-2), which is a key enzyme involved in the synthesis of 15-deoxy- Δ12,14 -prostaglandin J2 in BV-2 cells. Conclusion: We postulated that ALA enhances oAβ 1–42 phagocytosis by upregulating the COX-2/15-deoxy- Δ12,14 -prostaglandin J2/PPAR-γ/CD36 pathway in BV-2 cells. Finally, future studies should be conducted with an in vivo study to confirm the findings.
    Type of Medium: Online Resource
    ISSN: 1663-4365
    URL: Article
    DOI: 10.3389/fnagi.2021.788723
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2558898-9
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  • 5
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    Effect of Ruellia tuberosa L. on aorta endothelial damage‐associated factors in high‐fat diet and streptozotocin‐induced type 2 diabetic rats
    Wiley ; 2019
    In:  Food Science & Nutrition Vol. 7, No. 11 ( 2019-11), p. 3742-3750
    Details
    In: Food Science & Nutrition, Wiley, Vol. 7, No. 11 ( 2019-11), p. 3742-3750
    Abstract: Hyperglycemia plays crucial roles in vascular disease development, including macrovascular and microvascular diseases from diabetes mellitus (DM). Our previous study demonstrated that Ruellia tuberosa L. (RTL) aqueous and ethanol extracts alleviate hyperglycemia and inhibit insulin resistance in diabetic rats. This study investigated the protective effect of RTL ethanol extract against aorta dysfunction in high‐fat diet (HFD) and streptozotocin (STZ)‐induced type 2 DM (T2DM) rats. Results showed that RTL ethanol extract (100 and 400 mg/kg BW/day) ameliorated serum lipid profiles, including triglyceride, free fatty acid, low‐density lipoprotein cholesterol, very low‐density lipoprotein cholesterol, and high‐density lipoprotein cholesterol levels. It also significantly reduced the level of serum cytokines such as tumor necrosis factor‐α (TNF‐α) and interleukin‐6 in T2DM rats. Additionally, RTL extract decreased endothelin‐1 and endothelial nitric oxide contents, reduced the level of cell adhesion factors, including monocyte chemoattractant protein‐1 and cell adhesion factor vascular cell adhesion molecule‐1, while decreasing content of damage factors, namely tissue factor and von Willebrand factor in aortic tissues of diabetic rats. Equally noteworthy is that RTL extract enhanced the activity of aorta antioxidative enzymes, including superoxidase dismutase and catalase in diabetic rats, suggesting that RTL ethanol extract may ameliorate aorta dysfunction via enhancing aortic antioxidative enzyme activity, which subsequently suppresses aorta endothelial damage‐associated factors in HFD with STZ‐induced T2DM rats.
    Type of Medium: Online Resource
    ISSN: 2048-7177 , 2048-7177
    URL: Issue
    URL: Article
    DOI: 10.1002/fsn3.v7.11
    DOI: 10.1002/fsn3.1233
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 2703010-6
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  • 6
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    Alleviative effects of α‐lipoic acid on muscle atrophy via the modulation of TNF ‐α/ JNK and PI3K / AKT pathways in high‐fat diet and streptozotocin‐induced type 2 diabetic rats
    Wiley ; 2023
    In:  Food Science & Nutrition Vol. 11, No. 4 ( 2023-04), p. 1931-1939
    Details
    In: Food Science & Nutrition, Wiley, Vol. 11, No. 4 ( 2023-04), p. 1931-1939
    Abstract: Diabetes mellitus (DM) is often accompanied by clinical complications such as sarcopenia. Previous studies have indicated that oxidative stress and insulin resistance (IR) are highly associated with the pathogenesis of diabetic myopathy. α‐lipoic acid (ALA), a potent biological antioxidant, exists abundantly in a variety of plants and vegetables. This study aimed to investigate the ameliorative effect of ALA on muscle atrophy in type 2 diabetic rats induced by high‐fat diet feeding (HFD) plus streptozotocin (STZ) injection. The HFD/STZ‐induced diabetic rats were orally administered 50, 100, or 200 mg/kg body weight ALA once a day for 13 weeks. The results showed that ALA at the tested concentrations significantly increased the soleus muscle mass and muscle fibers in diabetic rats. Proinflammatory cytokines, such as tumor necrosis factor (TNF)‐α, were found to decrease in both the serum and muscle of ALA‐treated diabetic rats. ALA significantly reduced the protein‐expression levels of phosphorylated c‐Jun N‐terminal kinase (pJNK)/JNK, forkhead box O3 (FOXO3), and muscle ring‐finger protein‐1 (Murf1); whereas, it enhanced the protein‐expression levels of phosphoinositide 3‐kinase (PI3K), phosphorylated protein kinase B (pAKT)/AKT, myogenin determination gene D (MyoD), the mechanistic target of rapamycin (mTOR), and myosin heavy chain (MyHC) in the soleus muscle of diabetic rats. The results from this study suggested that ALA treatment may preserve soleus muscle mass, alleviate muscle atrophy by suppressing the TNF‐α/JNK pathway, and ameliorate the PI3K/AKT pathway in HFD/STZ‐induced type 2 diabetic rats.
    Type of Medium: Online Resource
    ISSN: 2048-7177 , 2048-7177
    URL: Issue
    URL: Article
    DOI: 10.1002/fsn3.v11.4
    DOI: 10.1002/fsn3.3227
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2703010-6
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  • 7
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    Gelatin versus its two major degradation products, prolyl‐hydroxyproline and glycine, as supportive therapy in experimental colitis in mice
    Wiley ; 2018
    In:  Food Science & Nutrition Vol. 6, No. 4 ( 2018-06), p. 1023-1031
    Details
    In: Food Science & Nutrition, Wiley, Vol. 6, No. 4 ( 2018-06), p. 1023-1031
    Abstract: Gelatin is an anti‐inflammatory dietary component, and its predominant metabolites entering circulation are prolyl‐hydroxyproline (Pro‐Hyp) and glycine. We evaluated the protective effects of orally administered gelatin, glycine, and Pro‐Hyp 10:3:0.8 (w/w/w) against dextran sodium sulfate ( DSS )‐induced colitis in mice. According to clinical, histological, and biochemical parameters, they exhibited significant activities in the order of gelatin 〈 glycine 〈 Pro‐Hyp. Gelatin prevented the DSS ‐induced increase in interleukin‐1β ( IL ‐1β), interleukin‐6 ( IL ‐6), and tumor necrosis factor‐α ( TNF ‐α) in the colon, rather than in peripheral blood. Glycine and Pro‐Hyp attenuated the DSS ‐induced rise in colonic IL ‐6 and TNF ‐α, as well as peripheral IL ‐1β, IL ‐6, and TNF ‐α. Hematologic results show the attenuation of DSS ‐induced leukocytosis and lymphocytosis by glycine and Pro‐Hyp, rather than gelatin. These findings suggest that glycine and Pro‐Hyp constitute the material basis for gelatin's anticolitis efficacy, and they have better anticolitis activities and distinct mechanisms of action when ingested as free compounds than as part of gelatin.
    Type of Medium: Online Resource
    ISSN: 2048-7177 , 2048-7177
    URL: Issue
    URL: Article
    DOI: 10.1002/fsn3.2018.6.issue-4
    DOI: 10.1002/fsn3.639
    Language: English
    Publisher: Wiley
    Publication Date: 2018
    detail.hit.zdb_id: 2703010-6
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  • 8
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    Enzymatic catalysis for sustainable production of high omega‐3 triglyceride oil using imidazolium‐based ionic liquids
    Wiley ; 2018
    In:  Food Science & Nutrition Vol. 6, No. 8 ( 2018-11), p. 2020-2027
    Details
    In: Food Science & Nutrition, Wiley, Vol. 6, No. 8 ( 2018-11), p. 2020-2027
    Abstract: Two different fish oil preparations, namely triglycerides and ethyl esters containing, respectively, 30.02% and 74.38% of omega‐3 fatty acids, were employed as the substrates for transesterification. Catalyzed by immobilized lipase using imidazolium‐based ionic liquid systems, the total content of eicosapentaenoic acid ( EPA ) and docosahexaenoic acid ( DHA ) in the resulting triglyceride reached 63.60% when 4% hydrophobic ionic liquid was used, which was 11.74% higher than that of the triglyceride produced in a solvent‐free reaction system. The activation energy of the product (triglyceride‐type fish oil) was 173.64 KJ mol −1 , which was not significantly different from that of the commercial ethyl ester‐type fish oil, so were the other thermal oxidative kinetic parameters. The kinetic parameters depicting the thermal and oxidative stability of the fish oil product provide the basis for industrial processing, storage, and applications.
    Type of Medium: Online Resource
    ISSN: 2048-7177 , 2048-7177
    URL: Issue
    URL: Article
    DOI: 10.1002/fsn3.2018.6.issue-8
    DOI: 10.1002/fsn3.733
    Language: English
    Publisher: Wiley
    Publication Date: 2018
    detail.hit.zdb_id: 2703010-6
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  • 9
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    Alleviative effect of Ruellia tuberosa L. on NAFLD and hepatic lipid accumulation via modulating hepatic de novo lipogenesis in high‐fat diet plus streptozotocin‐induced diabetic rats
    Wiley ; 2020
    In:  Food Science & Nutrition Vol. 8, No. 10 ( 2020-10), p. 5710-5716
    Details
    In: Food Science & Nutrition, Wiley, Vol. 8, No. 10 ( 2020-10), p. 5710-5716
    Abstract: Ruellia tuberos a L. (RTL) exhibits phytochemical activities and has been used as a folk medicine for curing diabetes mellitus in East Asia for decades. This study investigated the effect of RTL aqueous and ethanolic extracts on nonalcoholic fatty liver disease (NAFLD) and hepatic lipid accumulation in high‐fat diet (HFD) and streptozotocin (STZ)‐induced type 2 diabetes mellitus (T2DM) rats. Administration of RTL aqueous extract (RTLW) or ethanolic extract (RTLE) at dosage of 100 or 400 mg/kg body weight for 4 weeks was carried out in HFD/STZ‐induced T2DM rats. Liver weight, adipose (epididymal and perirenal adipose tissues) weight, hepatic triglyceride level, and de novo lipogenesis (DNL)‐associated protein expression were monitored after scarification. The results revealed that RTLW and RTLE reduced relative liver weight and relative fat weights in HFD/STZ‐induced T2DM rats. RTLW and RTLE also ameliorated NAFLD and hepatic triglyceride (TG) accumulation in diabetic rats. Moreover, hepatic DNL‐regulated enzymes such as sterol regulatory element‐binding protein‐1 (SREBP1) and fatty acid synthase (FAS) expression were significantly suppressed by RTLE (100 and 400 mg/kg body weight) in diabetic rats. The evidences of this study suggest that RTL possesses potential on alleviating NAFLD and lipid accumulation via regulating DNL in the liver of HFD/STZ‐induced T2DM rats.
    Type of Medium: Online Resource
    ISSN: 2048-7177 , 2048-7177
    URL: Issue
    URL: Article
    DOI: 10.1002/fsn3.v8.10
    DOI: 10.1002/fsn3.1868
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2703010-6
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  • 10
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    The ART and LOGIC of scholarly communication: Effective skills for publication and beyond
    Wiley ; 2022
    In:  Food Science & Nutrition Vol. 10, No. 4 ( 2022-04), p. 981-984
    Details
    In: Food Science & Nutrition, Wiley, Vol. 10, No. 4 ( 2022-04), p. 981-984
    Abstract: Based on a series of well‐recognized workshops around the world conducted by the author with more than 15 years of EIC experience, this article highlights the essence and spirit of publishing scholarly outcomes for authors in science and engineering. It is vital for all scientists who intend to upgrade their publications to bear in mind that, additional to KISS (Keep It Simple and Straightforward), the contents of a manuscript should be prepared based on the core concept of ART and LOGIC, namely: Thoroughness (be thorough when compiling) Complete the sentence, paragraph, and article Readability (keep the expression readable) Know what you mean and mean what you know Articulateness (be articulate in wording) Be polite yet firm, when necessary, with controversies and Lock one in ASAP Identify and be identical with the readers Offer useful information Justification and reasoning are most critical Gain confidence Put forth best methodology and know‐how Indication of good will Be constructive even when criticism is needed Conclusive statement Provide solid conclusion with proper outlook
    Type of Medium: Online Resource
    ISSN: 2048-7177 , 2048-7177
    URL: Issue
    URL: Article
    DOI: 10.1002/fsn3.v10.4
    DOI: 10.1002/fsn3.2766
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2703010-6
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