In:
Prenatal Diagnosis, Wiley, Vol. 43, No. 9 ( 2023-08), p. 1120-1131
Kurzfassung:
What is already known about this topic? Diagnostic testing is recommended following the diagnosis of fetal anomalies, high‐probability cell‐free DNA and for targeted familial variants for neonatal and pediatric onset conditions. Postnatal genetic testing for neonates at risk of genetic conditions has been shown to have implications for medical management. What does this study add? Utilization of cord blood for genetic testing in prenatally identified high‐probability fetuses has not been described previously. Genetic testing on cord blood for fetuses at high risk for genetic conditions in the setting of fetal anomalies, high‐probability cfDNA, and family history has a high uptake and yield with implications for neonatal management. Genetic testing from cord blood is low risk for maternal cell contamination.
Materialart:
Online-Ressource
ISSN:
0197-3851
,
1097-0223
Sprache:
Englisch
Verlag:
Wiley
Publikationsdatum:
2023
ZDB Id:
1491217-X
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