In:
Magnetic Resonance in Chemistry, Wiley, Vol. 59, No. 1 ( 2021-01), p. 16-22
Abstract:
Swainsonine (SW, 1 ), a unique indolizine with poly‐hydroxyl groups, was re‐isolated from the plant endophytic fungus Alternaria oxytropis. The structure (including planar structure and relative configuration) was systematically elucidated by NMR spectra (including 1 H, 13 C, 1 H‐ 1 H COSY, HMQC, HMBC, and NOESY spectra in DMSO‐ d 6 and in CD 3 OD); 1 H NMR spectra of the modified Mosher's products were first used to determine the absolute configuration of SW. More importantly, the complex coupled features of H‐7α, H‐7β, and H‐6α in the 1 H NMR spectrum of ( 1 ) were analyzed in details, which will provide aids for the planar and relative configuration determination of analogs.
Type of Medium:
Online Resource
ISSN:
0749-1581
,
1097-458X
Language:
English
Publisher:
Wiley
Publication Date:
2021
detail.hit.zdb_id:
1475029-6
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