In:
PLOS Neglected Tropical Diseases, Public Library of Science (PLoS), Vol. 15, No. 3 ( 2021-3-18), p. e0009113-
Abstract:
Bats can harbor zoonotic pathogens causing emerging infectious diseases, but their status as hosts for bacteria is limited. We aimed to investigate the distribution, prevalence and genetic diversity of Borrelia in bats and bat ticks in Hubei Province, China, which will give us a better understanding of the risk of Borrelia infection posed by bats and their ticks. During 2018–2020, 403 bats were captured from caves in Hubei Province, China, 2 bats were PCR-positive for Borrelia . Sequence analysis of rrs , flaB and glpQ genes of positive samples showed 99.55%-100% similarity to Candidatus Borrelia fainii, a novel human-pathogenic relapsing fever Borrelia species recently reported in Zambia, Africa and Eastern China, which was clustered together with relapsing fever Borrelia species traditionally reported only in the New World. Multilocus sequence typing (MLST) and pairwise genetic distances further confirmed the Borrelia species in the bats from Central China as Candidatus Borrelia fainii. No Borrelia DNA was detected in ticks collected from bats. The detection of this human-pathogenic relapsing fever Borrelia in bats suggests a wide distribution of this novel relapsing fever Borrelia species in China, which may pose a threat to public health in China.
Type of Medium:
Online Resource
ISSN:
1935-2735
DOI:
10.1371/journal.pntd.0009113
DOI:
10.1371/journal.pntd.0009113.g001
DOI:
10.1371/journal.pntd.0009113.g002
DOI:
10.1371/journal.pntd.0009113.g003
DOI:
10.1371/journal.pntd.0009113.t001
DOI:
10.1371/journal.pntd.0009113.t002
DOI:
10.1371/journal.pntd.0009113.s001
DOI:
10.1371/journal.pntd.0009113.s002
DOI:
10.1371/journal.pntd.0009113.s003
DOI:
10.1371/journal.pntd.0009113.s004
DOI:
10.1371/journal.pntd.0009113.s005
DOI:
10.1371/journal.pntd.0009113.s006
DOI:
10.1371/journal.pntd.0009113.s007
DOI:
10.1371/journal.pntd.0009113.s008
DOI:
10.1371/journal.pntd.0009113.s009
DOI:
10.1371/journal.pntd.0009113.s010
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2021
detail.hit.zdb_id:
2429704-5
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