In:
Journal of Cancer Research Updates, Neoplasia Research, Vol. 4, No. 2 ( 2015-04-29)
Abstract:
In clinical, Psychotria serpens L. was often substitute for Caulis trachelospermi to treat cancer in China. Meanwhile, EtOAc and n-BuOH fractions of MeOH extract of P. serpens L. show power activity against H460, HepG2, Hela, and PC9/GR cell lines, and no toxic effects against normal 16HBE cell lines. In order to search significant anti-cancer active leading compounds, sevenetin (5), rutin (6), kaempferol-3- flavonoids, quercetin (1), tamarixetin-3-O-rutinoside (2), quercetin 3-O-(2G-β-D-xylopyranosy-lrutinoside) (3), kaempferol (4), tamarixO- rutino- side (7) were isolated from P. serpens L., and their structures were identified through spectroscopic techniques including NMR (1D and 2D) and MS. 2-5 were the first isolated from genus Psychotria. All of compounds were the first isolated from P. serpens.
Type of Medium:
Online Resource
ISSN:
1929-2279
DOI:
10.6000/1929-2279.2015.04.02.3
Language:
Unknown
Publisher:
Neoplasia Research
Publication Date:
2015
detail.hit.zdb_id:
2810590-4
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