In:
BMC Gastroenterology, Springer Science and Business Media LLC, Vol. 22, No. 1 ( 2022-12)
Abstract:
Cecal ulcers are
sometimes encountered in asymptomatic individuals. Their clinical outcomes and management recommendations remain uncertain. Methods Asymptomatic patients who underwent a colonoscopic exam
for colon cancer screening were retrospectively reviewed from July 2009 to November 2016. Patients with cecal ulcers were included. Patients who had
colorectal symptoms, such as abdominal pain, had nonsteroidal anti-inflammatory drugs or were lost to follow-up were excluded. Results A total of 34,036 patients underwent colon cancer
screening. Cecal ulcers were found in 35 patients. After exclusion, 24 patients (mean duration, 52 months) received follow-up colonoscopy. In 20 patients,
(83.3%), cecal ulcer resolved without intervention, but 4 patients (16.7%) developed clinical significant diseases, including intestinal tuberculosis
(n = 2), Crohn’s disease (n = 1), and ulcerative colitis (n = 1). Patients who developed clinically significant diseases had a higher percentage of ulcers
larger than 1 cm (75% vs. 15%, p = 0.035), terminal ileum involvement (100% vs.
15.4%, p = 0.006) and ulcers with irregular fold (75% vs. 5%, p = 0.008). Conclusions In patients with
asymptomatic cecal ulcers, the endoscopic features included larger ulcer size, terminal ileum involvement and ulcers with irregular fold may predict
development of clinically significant diseases. If the above-mentioned features are present, even asymptomatic patients should be closely monitored.
Type of Medium:
Online Resource
ISSN:
1471-230X
DOI:
10.1186/s12876-022-02383-x
Language:
English
Publisher:
Springer Science and Business Media LLC
Publication Date:
2022
detail.hit.zdb_id:
2041351-8
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