In:
Polymer Chemistry, Royal Society of Chemistry (RSC), Vol. 13, No. 30 ( 2022), p. 4436-4445
Abstract:
Polymers bearing amine moieties are highly valuable for their ability to conjugate and/or complex a variety of molecules. However, their incorporation into synthetic macromolecules remains challenging. Poly(2-oxazolines) (POx) are a highly functional class of polymers, which through the choice of polymerization components or post-polymerization modifications, can be furnished with a large range of functional groups. Here, we explored their potential for the preparation of α-amine telechelic macromolecules through a comprehensive comparison of different amine-containing cationic ring-opening polymerization (CROP) initiators comprised of the amine protecting groups tert -butyloxycarbonyl (BOC) and phthalimide and the counterions tosylate (Tos) and bromide (Br). Polymerization kinetics of 2-ethyl-2-oxazoline (EtOx) and stability tests revealed the commercially available phthalimide-NH 2 -C3-Br as the most suitable initiator for achieving the highest degree of control over the polymerization. The polymerization initiated by this new initiator at 140 °C under microwave irradiation was characterized by a stable protected amine group, and fast initiation, and delivered well-defined poly(2-ethyl-2-oxazoline)s (PEtOx). α-Amine telechelic PEtOx were subsequently synthesized using different terminating agents, enabling the future preparation of tailored aminated POx-based architectures.
Type of Medium:
Online Resource
ISSN:
1759-9954
,
1759-9962
Language:
English
Publisher:
Royal Society of Chemistry (RSC)
Publication Date:
2022
detail.hit.zdb_id:
2528812-X
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