In:
PLOS ONE, Public Library of Science (PLoS), Vol. 18, No. 5 ( 2023-5-11), p. e0284951-
Abstract:
Magnetic resonance imaging is an important tool for characterizing volumetric changes of the piglet brain during development. Typically, an early step of an imaging analysis pipeline is brain extraction, or skull stripping. Brain extractions are usually performed manually; however, this approach is time-intensive and can lead to variation between brain extractions when multiple raters are used. Automated brain extractions are important for reducing the time required for analyses and improving the uniformity of the extractions. Here we demonstrate the use of Mask R-CNN, a Region-based Convolutional Neural Network (R-CNN), for automated brain extractions of piglet brains. We validate our approach using Nested Cross-Validation on six sets of training/validation data drawn from 32 pigs. Visual inspection of the extractions shows acceptable accuracy, Dice coefficients are in the range of 0.95–0.97, and Hausdorff Distance values in the range of 4.1–8.3 voxels. These results demonstrate that R-CNNs provide a viable tool for skull stripping of piglet brains.
Type of Medium:
Online Resource
ISSN:
1932-6203
DOI:
10.1371/journal.pone.0284951
DOI:
10.1371/journal.pone.0284951.g001
DOI:
10.1371/journal.pone.0284951.g002
DOI:
10.1371/journal.pone.0284951.g003
DOI:
10.1371/journal.pone.0284951.g004
DOI:
10.1371/journal.pone.0284951.g005
DOI:
10.1371/journal.pone.0284951.g006
DOI:
10.1371/journal.pone.0284951.s001
DOI:
10.1371/journal.pone.0284951.s002
DOI:
10.1371/journal.pone.0284951.s003
DOI:
10.1371/journal.pone.0284951.r001
DOI:
10.1371/journal.pone.0284951.r002
DOI:
10.1371/journal.pone.0284951.r003
DOI:
10.1371/journal.pone.0284951.r004
DOI:
10.1371/journal.pone.0284951.r005
DOI:
10.1371/journal.pone.0284951.r006
DOI:
10.1371/journal.pone.0284951.r007
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2023
detail.hit.zdb_id:
2267670-3
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