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  • 1
    Online Resource
    Online Resource
    Sociological Review Foundation ; 2022
    In:  The Sociological Review Magazine
    In: The Sociological Review Magazine, Sociological Review Foundation
    Type of Medium: Online Resource
    ISSN: 2754-1371
    Language: Unknown
    Publisher: Sociological Review Foundation
    Publication Date: 2022
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  • 2
    Online Resource
    Online Resource
    Wiley ; 1995
    In:  Acta Physiologica Scandinavica Vol. 155, No. 4 ( 1995-12), p. 363-376
    In: Acta Physiologica Scandinavica, Wiley, Vol. 155, No. 4 ( 1995-12), p. 363-376
    Abstract: The extracellular receptor currents evoked by step displacements of the otolithic membrane of the isolated saccular macula of Rana esculenta were recorded under transepthelial voltage clamp conditions. With the aim to depolarize the hair cells and increase the fractional resistance of the apical membrances, the basal side of the preparation was bathed in saline with an increased K + concentration (62 mm). This caused a shift in the non‐linear receptor current‐voltage relation along the voltage axis of ‐51 mVpL10 mV; (mean pL SD; n= 32) and a reduction in the transepithelial resistance of 10%. Under these conditions the electrical properties of the macula are assumed to be controlled by the apical membranes. The effects of different concentrations of Ca 2+ in the apical solution on the receptor current‐voltage relation were examined. Change of the apical Ca 2+ concentration (range 3 mM to 70 μM) varied the transepithelial voltage at which the receptor current was zero (V rev ). Fitting a modified constant field equation to the relation between the apical Ca 2+ concentration and the change in V rev gave an estimate of P ca /P k of the transduction channels of 212. Furthermore, a high relative permeability of the transduction channels for other divalent cations (Ba 2+ , Sr 2+ ) was measured, whereas Mn 2+ inhibited the receptor current. The receptor current was inhibited by amiloride (IC 50 3.2 μM) and nifedipine (IC 50 1.9 μM pL0.6 μM). Reduction of the apical Ca 2+ concentration to 90μM in standard apical solution reduced the size of the receptor current to 67% pL 30% (n=17) compared to control but did not affect the shape of the receptor current ‐voltage relation. Subsequent substitution of K + by Na + caused a further reduction of the receptor current to 32% pL29% (n=9), changed the receptor current‐voltage relation into a linear relation and diminished the adaptation of the receptor current. These results indicate that the mechano‐electrical transduction channels of the frog saccular hair cells are highly selective to Ca 2+ and that the conductance of the channels may be influenced by the apical monovalent cation species.
    Type of Medium: Online Resource
    ISSN: 0001-6772 , 1365-201X
    URL: Issue
    RVK:
    Language: English
    Publisher: Wiley
    Publication Date: 1995
    detail.hit.zdb_id: 2012166-0
    detail.hit.zdb_id: 101-6
    SSG: 12
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  • 3
    Online Resource
    Online Resource
    Frontiers Media SA ; 2022
    In:  Frontiers in Marine Science Vol. 9 ( 2022-5-31)
    In: Frontiers in Marine Science, Frontiers Media SA, Vol. 9 ( 2022-5-31)
    Abstract: Recreational sea angling is an important recreational activity in the United Kingdom with around 1.6% of adults participating and a total economic impact of around £1.5 billion each year. There are positive impacts of angling on physical health and mental well-being. The COVID-19 pandemic resulted in several national lockdowns in the UK, which along with additional local restrictions and personal circumstances due to the pandemic, have impacted people’s ability to fish. Angling was not allowed in the UK for some of the first lockdown (March to May 2020), and further restrictions were implemented subsequently that varied between the countries and regions. The impact of COVID-19 on the participation, effort, physical activity, and well-being of UK sea anglers remains unknown. A panel of UK sea anglers, which record their activity and catches as part of the Sea Angling Diary Project, were surveyed to assess changes in sea angling participation, physical activity, mental well-being, and expenditure between 2019 and 2020. We compared the sea angling effort and catches of the diary panel between 2019 and 2020. We found reduced sea angling effort in the panel, including sessions and catches, between 2019 and 2020, with the largest impact being in April 2020. We found that there was a significant reduction in expenditure during April 2020 with 64% of respondents spending less on sea angling than in a typical April. In total, 67% of respondents reported reduced happiness and 45% were less active due to sea angling restrictions. Using a general linear model, we found that even though anglers said that being able to go fishing has resulted in high World Health Organization Five Well-being Index scores, other factors also had significant effects. These included: age; physical and mental health status; angling activity; travel to fish during COVID-19; and whether they fished in July 2020. Of those who responded, 66% classified themselves as at either high or moderate risk to COVID-19. This work has shown that COVID-19 has negatively affected marine recreational fisheries in the UK, and not being able to go sea angling has negatively impacted participation, effort, physical activity and well-being.
    Type of Medium: Online Resource
    ISSN: 2296-7745
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2757748-X
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