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  • 1
    Online Resource
    Online Resource
    Institute of Electrical and Electronics Engineers (IEEE) ; 2024
    In:  IEEE Robotics and Automation Letters Vol. 9, No. 6 ( 2024-6), p. 5284-5291
    In: IEEE Robotics and Automation Letters, Institute of Electrical and Electronics Engineers (IEEE), Vol. 9, No. 6 ( 2024-6), p. 5284-5291
    Type of Medium: Online Resource
    ISSN: 2377-3766 , 2377-3774
    Language: Unknown
    Publisher: Institute of Electrical and Electronics Engineers (IEEE)
    Publication Date: 2024
    detail.hit.zdb_id: 2844561-2
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  • 2
    In: Bioorganic & Medicinal Chemistry, Elsevier BV, Vol. 41 ( 2021-07), p. 116209-
    Type of Medium: Online Resource
    ISSN: 0968-0896
    RVK:
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2021
    detail.hit.zdb_id: 1501507-5
    SSG: 15,3
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  • 3
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2013
    In:  Chemical Papers Vol. 67, No. 2 ( 2013-01-1)
    In: Chemical Papers, Springer Science and Business Media LLC, Vol. 67, No. 2 ( 2013-01-1)
    Abstract: Possibilities of a multicell isoperibolic-semiadiabatic calorimeter application for the measurement of hydration heat and maximum temperature reached in mixtures of various compositions during their setting and early stages of hardening are presented. Measurements were aimed to determine the impact of selected components’ content on the course of ordinary Portland cement (OPC) hydration. The following components were selected for the determination of the hydration behaviour in mixtures: very finely ground granulated blast furnace slag (GBFS), silica fume (microsilica, SF), finely ground quartz sand (FGQ), and calcined bauxite (CB). A commercial polycarboxylate type superplasticizer was also added to the selected mixtures. All maximum temperatures measured for selected mineral components were lower than that reached for cement. The maximum temperature increased with the decreasing amount of components in the mixture for all components except for silica fume. For all components, except for CB, the values of total released heat were higher than those for pure Portland cement samples.
    Type of Medium: Online Resource
    ISSN: 1336-9075
    Language: Unknown
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2013
    detail.hit.zdb_id: 2252770-9
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  • 4
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2014
    In:  Chemical Papers Vol. 68, No. 1 ( 2014-01-1)
    In: Chemical Papers, Springer Science and Business Media LLC, Vol. 68, No. 1 ( 2014-01-1)
    Abstract: A multicell isoperibolic — semiadiabatic calorimeter was used for the measurement of temperature and the determination of the hydration heat evolution at earlier period of cement pastes setting and hardening. The measurements were aimed at the determination of the effect of superplasticizers (SPs) on the course of the Portland cement hydration. Commercial polycarboxylate SP was added to the mixtures and the heat effect was measured. With the increasing content of SP, the hydration temperature increased up to a certain value and then decreased. In case of a sufficient amount of water in the mixture to achieve complete hydration of cement, samples with the highest values of the maximum hydration temperature reached the highest values of the released total heat. If there is not a sufficient amount of water to achieve complete hydration, the samples with the highest values of the maximum hydration temperature reach the lowest values of the released total heat.
    Type of Medium: Online Resource
    ISSN: 1336-9075
    Language: Unknown
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2014
    detail.hit.zdb_id: 2252770-9
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  • 5
    In: Future Medicinal Chemistry, Future Science Ltd, Vol. 13, No. 22 ( 2021-11), p. 1945-1962
    Abstract: Background: Increasing resistance has resulted in an urgent need for new antimicrobial drugs. A systematic me-too approach was chosen to modify clinically used sulfonamides to obtain their imines. Methods &  results: Twenty-five compounds were synthesized and evaluated for their antibacterial activity. The most active compounds were also investigated against methicillin- and trimethoprim/sulfamethoxazole (SMX)-resistant Gram-positive species. Staphylococci shared the highest susceptibility including resistant strains with minimum inhibitory concentrations from 3.91 μM (≥2.39 μg ml -1 ). Crucially, the compounds inhibit MRSA and trimethoprim/SMX-resistant Staphylococci without any cross-resistance. Modification of parent sulfonamides turned a bacteriostatic effect into a bactericidal effect. Toxicity for HepG2 and hemolytic properties were also determined. Conclusions: The presence of a dihalogenated salicylidene moiety is required for optimal activity. Based on toxicity, promising derivatives for further investigation were identified.
    Type of Medium: Online Resource
    ISSN: 1756-8919 , 1756-8927
    Language: English
    Publisher: Future Science Ltd
    Publication Date: 2021
    SSG: 15,3
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  • 6
    In: Journal of Ophthalmology, Hindawi Limited, Vol. 2021 ( 2021-10-7), p. 1-10
    Abstract: Purpose. To evaluate a 12-year follow-up of myopic patients after iris-fixated phakic intraocular lenses (IF pIOLs) implantation. Setting. Ophthalmology Department, Military University Hospital in Prague (Czech Republic). Design. Single-center retrospective cohort study. Methods. We describe the results of a cohort study that included 85 eyes of 46 myopic patients who underwent implantation of Verisyse myopia, Veriflex, and Verisyse myopia toric (all Abbott Medical Optics, Inc.) intraocular lenses. Refractive functions and adverse events were assessed preoperatively, at 6 months, and 1, 2, 5, and 12 years after IF pIOL implantation. Results. Mean spherical equivalent was measured as −9.37 ± 2.87 D, 0.14 ± 0.61 D, and −0.42 ± 1.08 D, preoperatively, at 6 months and 12 years postoperatively, respectively. There was a significant reduction in the cylinder after surgery. At 12 years postoperatively, 90% of eyes had uncorrected distance visual acuity (UDVA) of 20/40 and 64% of 20/20. The safety index was 1.10 for the whole postoperative follow-up period. We found cataract formation in 3 eyes (3.5%). The endothelial cells loss (EC loss) directly caused by IF pIOL implantation was 6.0%, 8.10%, 12.8%, and 11.9%, at 1, 2, 5, and 12 years, respectively. In our cohort, 95% of eyes lost a higher percentage of EC than would be expected from a physiological loss at 12 years postoperatively. We found a significant negative interaction between preoperative pachymetry and EC loss, indicating that the lower pachymetry leads to a faster decline in endothelial cells density (ECD). IF pIOL re-enclavation was found in 28% of eyes. 7% of subluxations were caused by trauma. The mean time of nontraumatic re-enclavation was 6 years postoperatively. Conclusions. The study confirmed the advantages of IF pIOL implantation due to rapid visual recovery and stable visual function over the 12-year follow-up and also showed the influence of lower corneal pachymetry regarding EC loss.
    Type of Medium: Online Resource
    ISSN: 2090-0058 , 2090-004X
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2021
    detail.hit.zdb_id: 2546525-9
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  • 7
    In: Sensors, MDPI AG, Vol. 18, No. 10 ( 2018-09-23), p. 3212-
    Abstract: Optofluidics, a research discipline combining optics with microfluidics, currently aspires to revolutionize the analysis of biological and chemical samples, e.g., for medicine, pharmacology, or molecular biology. In order to detect low concentrations of analytes in water, we have developed an optofluidic device containing a nanostructured substrate for surface enhanced Raman spectroscopy (SERS). The geometry of the gold surface allows localized plasmon oscillations to give rise to the SERS effect, in which the Raman spectral lines are intensified by the interaction of the plasmonic field with the electrons in the molecular bonds. The SERS substrate was enclosed in a microfluidic system, which allowed transport and precise mixing of the analyzed fluids, while preventing contamination or abrasion of the highly sensitive substrate. To illustrate its practical use, we employed the device for quantitative detection of persistent environmental pollutant 1,2,3-trichloropropane in water in submillimolar concentrations. The developed sensor allows fast and simple quantification of halogenated compounds and it will contribute towards the environmental monitoring and enzymology experiments with engineered haloalkane dehalogenase enzymes.
    Type of Medium: Online Resource
    ISSN: 1424-8220
    Language: English
    Publisher: MDPI AG
    Publication Date: 2018
    detail.hit.zdb_id: 2052857-7
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  • 8
    Online Resource
    Online Resource
    Walter de Gruyter GmbH ; 2009
    In:  PJCT Vol. 11, No. 4 ( 2009-1-1), p. 52-56
    In: PJCT, Walter de Gruyter GmbH, Vol. 11, No. 4 ( 2009-1-1), p. 52-56
    Abstract: The mixing equipment for highly concentrated fine-grained suspensions must be designed differently from the equipment in which a suspension with a low concentration of the solid phase or bigger particles is mixed. It is due to the different rheological properties of the suspensions. In this work we are trying to find a suitable mixing system for a highly concentrated fine-grained suspension. The aim was to determine an effect of particular geometrical parameters of the tested mixing systems on a suspension process, especially from the energetic viewpoint. The energetic costs of all the used mixing systems were compared on the basis of the power consumption which was necessary for reaching the state of sufficient suspension movement in the whole mixed bulk. As a result, it was confirmed that multistage impellers can be used even in standard vessels (with a liquid level height equal to a vessel diameter) with a profit. During experiments, the state of sufficient movement was determined by a visual observation of the suspension at the vessel bottom, at the wall and also at the suspension level.
    Type of Medium: Online Resource
    ISSN: 1899-4741 , 1509-8117
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2009
    detail.hit.zdb_id: 2402116-7
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  • 9
    In: European Thyroid Journal, Bioscientifica, Vol. 11, No. 2 ( 2022-04-01)
    Abstract: Thyroid nodules are a common finding in the general population. The primary aim of the study was to determine the prevalence of thyroid nodules and cancer found by ultrasound (US) in women who underwent screening for thyroid dysfunction during pregnancy. Design A double-centric, retrospective, cohort study. Patients and methods We searched through medical records, including thyroid ultrasonography, of pregnant women who were positively screened for thyroid disorders (using thyroid-stimulating hormone and thyroid antibodies) from an unselected population (‘universal screening group’, n   = 690) and of women who underwent the testing based on the presence of clinical risk factors defined by American Thyroid Association (’case-finding group’, n   = 249). Results Prevalence of benign and malignant thyroid nodules was lower in the ‘universal screening group’ than in the ‘case-finding group’ (9.9% vs 17.7%, P = 0.002, and 0.9% vs 7.2%, P 〈 0.001, respectively). Consistently, the thyroid cancer rate was lower among the nodules in the ‘universal screening group’ than in the ‘case-finding group’ (8.1% vs 29.0%, P = 0.003). Ultrasound EU-TIRADS (European Thyroid Imaging and Reporting Data System) category ≥4 had a 95.8% sensitivity for thyroid cancer. In palpable nodules, the prevalence of cancer was significantly higher than in the non-palpable ones (44.0% vs 2.2%, P 〈 0.001). In a multivariate regression analysis, thyroid nodules were associated with a history of infertility and parity. Conclusions Compared to the data from cancer registries, universal screening allowed detecting thyroid cancer in pregnancy three to five times more frequently, but the cancer rate among nodules (8.1%) did not differ from the common population. US had very good sensitivity for thyroid cancer in pregnancy.
    Type of Medium: Online Resource
    ISSN: 2235-0802
    Language: Unknown
    Publisher: Bioscientifica
    Publication Date: 2022
    detail.hit.zdb_id: 2659767-6
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  • 10
    Online Resource
    Online Resource
    Institute of Organic Chemistry & Biochemistry ; 1978
    In:  Collection of Czechoslovak Chemical Communications Vol. 43, No. 3 ( 1978), p. 696-712
    In: Collection of Czechoslovak Chemical Communications, Institute of Organic Chemistry & Biochemistry, Vol. 43, No. 3 ( 1978), p. 696-712
    Type of Medium: Online Resource
    ISSN: 0010-0765 , 1212-6950
    Language: English
    Publisher: Institute of Organic Chemistry & Biochemistry
    Publication Date: 1978
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