In:
Endocrinology and Metabolism, Korean Endocrine Society, Vol. 36, No. 2 ( 2021-04-30), p. 322-338
Abstract:
Pheochromocytoma and paraganglioma (PPGLs) are rare catecholamine-secreting neuroendocrine tumors but can be life-threatening. Although most PPGLs are benign, approximately 10% have metastatic potential. Approximately 40% cases are reported as harboring germline mutations. Therefore, timely and accurate diagnosis of PPGLs is crucial. For more than 130 years, clinical, molecular, biochemical, radiological, and pathological investigations have been rapidly advanced in the field of PPGLs. However, performing diagnostic studies to localize lesions and detect metastatic potential can be still challenging and complicated. Furthermore, great progress on genetics has shifted the paradigm of genetic testing of PPGLs. The Korean PPGL task force team consisting of the Korean Endocrine Society, the Korean Surgical Society, the Korean Society of Nuclear Medicine, the Korean Society of Pathologists, and the Korean Society of Laboratory Medicine has developed this position statement focusing on the comprehensive and updated diagnosis for PPGLs.
Type of Medium:
Online Resource
ISSN:
2093-596X
,
2093-5978
DOI:
10.3803/EnM.2020.908
Language:
English
Publisher:
Korean Endocrine Society
Publication Date:
2021
detail.hit.zdb_id:
2802452-7
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