In:
The Anatomical Record, Wiley
Abstract:
The goal of this study is to assess the feasibility of airway geometry as a biomarker for autism spectrum disorder (ASD). Chest computed tomography images of children with a documented diagnosis of ASD as well as healthy controls were identified retrospectively. Fifty‐four scans were obtained for analysis, including 31 ASD cases and 23 controls. A feature selection and classification procedure using principal component analysis and support vector machine achieved a peak cross validation accuracy of nearly 89% using a feature set of eight airway branching angles. Sensitivity was 94%, but specificity was only 78%. The results suggest a measurable difference in airway branching angles between children with ASD and the control population.
Type of Medium:
Online Resource
ISSN:
1932-8486
,
1932-8494
Language:
English
Publisher:
Wiley
Publication Date:
2023
detail.hit.zdb_id:
2273240-8
detail.hit.zdb_id:
2109216-3
SSG:
12
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