In:
The Plant Journal, Wiley, Vol. 87, No. 3 ( 2016-08), p. 245-257
Abstract:
It is difficult to evaluate the functions of auxin and the biosynthesis pathways of indole‐3‐acetic acid using genetic approaches; chemical genetics is an alternative method. Here we show that L‐α‐aminooxy‐phenylpropionic acid ( AOPP ), an inhibitor of auxin biosynthesis, targets tryptophan aminotransferase. We synthesized novel compounds derived from AOPP to study the structure–activity relationships of inhibitors of tryptophan aminotransferase in vitro , and identified some that were more potent, and more specific, in inhibiting auxin levels. We designate these compounds ‘pyruvamines’.
Type of Medium:
Online Resource
ISSN:
0960-7412
,
1365-313X
DOI:
10.1111/tpj.2016.87.issue-3
Language:
English
Publisher:
Wiley
Publication Date:
2016
detail.hit.zdb_id:
2020961-7
SSG:
12
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