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  • 1
    Online-Ressource
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    Reduction of Intraocular Pressure and Aqueous Outflow Resistance After Modified 360-degree Suture Trabeculotomy
    Ovid Technologies (Wolters Kluwer Health) ; 2023
    In:  Journal of Glaucoma Vol. 32, No. 3 ( 2023-03), p. 204-209
    Details
    In: Journal of Glaucoma, Ovid Technologies (Wolters Kluwer Health), Vol. 32, No. 3 ( 2023-03), p. 204-209
    Kurzfassung: Decreasing aqueous outflow resistance at trabecular meshwork is the main mechanism of modified 360-degree suture trabeculotomy (ST), and the preoperative C-value, which shows aqueous outflow resistance, is likely to be useful for predicting intraocular pressure (IOP) reduction. Purpose: To clarify the mechanism of IOP reduction and the preoperative prognostic predictor of modified 360-degree ST. Materials and Methods: Forty-three eyes of 32 patients with glaucoma who underwent ST at Hokkaido University Hospital between April 2017 and February 2020 were enrolled. The records of postoperative IOP and coefficient of aqueous outflow (C-value) after ST were reviewed from clinical charts retrospectively. Preoperative IOP and C-values were also reviewed and considered as the baseline. Results: Although the differences were not significant, IOP decreased to 15.4±3.3 mm Hg at 3 months ( P =0.10) and 16.1±3.8 mm Hg at 6 months ( P =0.21). In addition, there were significant decreases in anti-glaucoma medication scores at both 3 and 6 months after surgery ( P 〈 0.01). The C-value increased significantly to 0.24±0.11 µL/min/mm Hg at 3 months ( P 〈 0.01) and increased significantly to 0.27±0.14 µL/min/mm Hg at 6 months ( P 〈 0.01). The rates of change in IOP were negatively correlated with that in the C-value at 3 months ( r =−0.49 P 〈 0.01) and 6 months ( r =−0.46 P 〈 0.01). The success rate (IOP 〈 21 mm Hg, IOP reduction 〉 20%) was greater in the low baseline C-value group (≤0.17) than high baseline C-value group ( 〉 0.17) ( P 〈 0.05), and the baseline IOP and C-values were statistically significant in association with the success ( P 〈 0.05) at 6 months. Conclusions: Increased conventional outflow by the elimination of the aqueous outflow resistance at the trabecular meshwork is the main mechanism of IOP reduction after ST. Preoperative examination of tonographic outflow facility may be useful for predicting the IOP reduction and outcome of ST.
    Materialart: Online-Ressource
    ISSN: 1057-0829
    URL: Article
    DOI: 10.1097/IJG.0000000000002135
    RVK:
    XA 10000
    Sprache: Englisch
    Verlag: Ovid Technologies (Wolters Kluwer Health)
    Publikationsdatum: 2023
    ZDB Id: 2060541-9
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 2
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    Surgical outcomes of partial ciliary body direct suturing under the scleral flap for traumatic cyclodialysis cleft: A five-case series
    SAGE Publications ; 2022
    In:  European Journal of Ophthalmology Vol. 32, No. 6 ( 2022-11), p. 3712-3719
    Details
    In: European Journal of Ophthalmology, SAGE Publications, Vol. 32, No. 6 ( 2022-11), p. 3712-3719
    Kurzfassung: Cyclodialysis cleft is an uncommon finding due to blunt ocular trauma. A larger and more chronic cyclodialysis requires surgical repair. The aim of this study was to introduce a minimally invasive suturing technique for the lens-sparing repair of traumatic cyclodialysis cleft and evaluate outcomes. Methods This study was a retrospective case series. The medical and surgical records of five patients with traumatic cyclodialysis cleft who underwent this surgery were reviewed. The surgeon (Y.S.) dissected a fornix-based conjunctival flap and created a 90° circumferential and limbal-based scleral flap. Several small incisions parallel to the limbus were made within the scleral bed 1.5 and 3 mm posterior to the limbus. After suprachoroidal fluid drainage, tiny bumps in the ciliary body were exposed from the incisions and sewn directly onto the scleral bed with 10-0 nylon sutures. Results The mean age of the patients was 37.8 ± 1.3 years. The mean duration from injury to surgery was 14.8 ± 16.7 months. Mean best-corrected visual acuity (BCVA) was 0.56 ± 0.70 and intraocular pressure (IOP) was 5.2 ± 1.9 mmHg. In all patients, IOP normalized and BCVA then returned to baseline following this procedure. Mean postoperative BCVA was 1.17 ± 0.86 and IOP was 17.8 ± 1.3 mmHg. Mean IOP and BCVA recovery times were 82.0 ± 139.6 and 294.3 ± 284.3 days, respectively. Conclusions Partial ciliary body direct suturing under the scleral flap is a less invasive surgical option without lensectomy and considered safe and effective as a primary surgical repair for traumatic cyclodialysis cleft.
    Materialart: Online-Ressource
    ISSN: 1120-6721 , 1724-6016
    URL: Article
    DOI: 10.1177/11206721221083718
    Sprache: Englisch
    Verlag: SAGE Publications
    Publikationsdatum: 2022
    ZDB Id: 1475018-1
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 3
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    Modified 360-degree suture trabeculotomy combined with phacoemulsification and intraocular lens implantation for glaucoma and coexisting cataract
    Ovid Technologies (Wolters Kluwer Health) ; 2016
    In:  Journal of Cataract and Refractive Surgery Vol. 42, No. 11 ( 2016-11), p. 1634-1641
    Details
    In: Journal of Cataract and Refractive Surgery, Ovid Technologies (Wolters Kluwer Health), Vol. 42, No. 11 ( 2016-11), p. 1634-1641
    Materialart: Online-Ressource
    ISSN: 0886-3350
    URL: Article
    DOI: 10.1016/j.jcrs.2016.08.016
    Sprache: Englisch
    Verlag: Ovid Technologies (Wolters Kluwer Health)
    Publikationsdatum: 2016
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 4
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    Continuous Intraocular Pressure Monitoring During Nocturnal Sleep in Patients With Obstructive Sleep Apnea Syndrome
    Association for Research in Vision and Ophthalmology (ARVO) ; 2016
    In:  Investigative Opthalmology & Visual Science Vol. 57, No. 6 ( 2016-05-26), p. 2824-
    Details
    In: Investigative Opthalmology & Visual Science, Association for Research in Vision and Ophthalmology (ARVO), Vol. 57, No. 6 ( 2016-05-26), p. 2824-
    Materialart: Online-Ressource
    ISSN: 1552-5783
    URL: Article
    DOI: 10.1167/iovs.16-19220
    Sprache: Englisch
    Verlag: Association for Research in Vision and Ophthalmology (ARVO)
    Publikationsdatum: 2016
    ZDB Id: 2009858-3
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 5
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    Changes in Intraocular Pressure in Single Ventricle Patients After the Glenn or Fontan Procedure
    Ovid Technologies (Wolters Kluwer Health) ; 2019
    In:  Journal of Glaucoma Vol. 28, No. 11 ( 2019-11), p. 1012-1014
    Details
    In: Journal of Glaucoma, Ovid Technologies (Wolters Kluwer Health), Vol. 28, No. 11 ( 2019-11), p. 1012-1014
    Kurzfassung: A positive correlation was observed between intraocular pressure (IOP) and central venous pressure (CVP) in patients with single ventricle (SV) during the perioperative period. IOP needs to be carefully monitored in the postoperative period after the Glenn and Fontan procedures, particularly the Glenn procedure. Purpose: SV is a cardiac malformation characterized by the existence of only 1 functional ventricle and is treated using the Glenn and Fontan procedures. Significant changes occur in CVP after these procedures. IOP has been reported to differ in the same individual when measured in a seated or supine position, which may be related to CVP. In the present study, we examined the relationship between CVP and IOP before and after surgery for SV. Patients and Methods: This study was a prospective, nonrandomized case series. All patients had SV and this study excluded those with eye diseases associated with ocular hypertension. We measured IOP before and after the Glenn or Fontan procedure. CVP was concurrently monitored. Results: Twenty-eight eyes of 14 patients with SV who underwent the Glenn (N=8) or Fontan (N=6) procedure were examined. Mean ages (±SD) were 2.6±0.7 months for the Glenn procedure and 24.0±2.7 months for the Fontan procedure. A correlation was observed between CVP and IOP in the perioperative period. IOP and CVP were both significantly higher after than before the Glenn and/or Fontan procedures. However, no relationship was noted between changes in IOP and CVP after the Glenn and/or Fontan procedures. Conclusions: Elevations in CVP significantly increased IOP in patients with SV who underwent the Glenn or Fontan procedure. IOP needs to be carefully monitored in the postoperative period after both procedures.
    Materialart: Online-Ressource
    ISSN: 1057-0829
    URL: Article
    DOI: 10.1097/IJG.0000000000001375
    RVK:
    XA 10000
    Sprache: Englisch
    Verlag: Ovid Technologies (Wolters Kluwer Health)
    Publikationsdatum: 2019
    ZDB Id: 2060541-9
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 6
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    Long-term Outcomes of Modified 360-Degree Suture Trabeculotomy for Uveitic Glaucoma Compared With Primary Open Angle Glaucoma
    Ovid Technologies (Wolters Kluwer Health) ; 2022
    In:  Journal of Glaucoma Vol. 31, No. 8 ( 2022-08), p. 682-688
    Details
    In: Journal of Glaucoma, Ovid Technologies (Wolters Kluwer Health), Vol. 31, No. 8 ( 2022-08), p. 682-688
    Kurzfassung: A Kaplan-Meier survival curve analysis showed no significant differences in success rates between uveitic glaucoma (UG) and primary open angle glaucoma (POAG) 120 months after modified 360-degree suture trabeculotomy, which was effective for both groups in the long term. Purpose: The aim of this study was to examine the outcomes of modified 360-degree suture trabeculotomy in patients with UG as compared with those with POAG. Patients and Methods: This was a retrospective, nonrandomized, and comparative case series study. Modified 360-degree trabeculotomy using a 5-0 nylon suture (S-LOT) was performed on 51 eyes of 51 patients (54.4±13.4 y) with UG between October 2005 and January 2012 at Hokkaido University Hospital. Age-matched patients with POAG who underwent S-LOT during the same period were enrolled as controls. Written informed consent was obtained from all patients enrolled in the present study. Surgical success was defined as an intraocular pressure (IOP) 〈 18 mm Hg with similar or lower doses of antiglaucoma medications. Kaplan-Meier survival curves of surgical failure were analyzed and compared between UG and POAG. Results: The mean follow-up periods (±SD) for UG and POAG were 104.8±44.0 and 98.1±36.3 months ( P =0.23), respectively. Mean preoperative IOP in UG and POAG were 34.9±11.0 and 25.3±9.4 mm Hg ( P 〈 0.001), respectively. After surgery, mean IOP in UG and POAG decreased to 12.0±4.1 and 13.8±3.2 mm Hg, respectively, at 60 months, and 12.1±5.6 and 12.4±1.8 mm Hg ( P =0.86), respectively, at 120 months. The Kaplan-Meier survival curve analysis showed no significant differences in success rates between UG and POAG at the end of the follow-up (Log-rank test, P =0.13). Success rates in UG and POAG were 70.0 and 62.5% at 60 months, and 67.5 and 41.2% at 120 months, respectively. Conclusion: These results suggest that S-LOT is effective for UG and POAG alike.
    Materialart: Online-Ressource
    ISSN: 1057-0829
    URL: Article
    DOI: 10.1097/IJG.0000000000002057
    RVK:
    XA 10000
    Sprache: Englisch
    Verlag: Ovid Technologies (Wolters Kluwer Health)
    Publikationsdatum: 2022
    ZDB Id: 2060541-9
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 7
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    Surgical Outcomes of Trabeculectomy in Uveitic Glaucoma: A Long-Term, Single-Center, Retrospective Case-Control Study
    Hindawi Limited ; 2021
    In:  Journal of Ophthalmology Vol. 2021 ( 2021-5-21), p. 1-8
    Details
    In: Journal of Ophthalmology, Hindawi Limited, Vol. 2021 ( 2021-5-21), p. 1-8
    Kurzfassung: Purpose. To evaluate the long-term outcomes of trabeculectomy with mitomycin C (MMC-TLE) in patients with uveitic glaucoma (UG). Patients and Methods. This was a retrospective, nonrandomized case series study. MMC-TLE was performed on 50 eyes with UG between February 2001 and January 2015 at Hokkaido University Hospital. Age- and sex-matched patients with primary open angle glaucoma (POAG) who underwent MMC-TLE were matched by age and sex and enrolled as controls. Surgical success was defined as an intraocular pressure (IOP) less than 18 or 15 mmHg. The Kaplan–Meier survival curves for surgical failure were analyzed. Results. The mean preoperative IOP in UG and POAG was 27.6 ± 10.6 and 18.0 ± 4.5 mmHg, respectively. After the surgery, the mean IOP in UG and POAG was reduced to 11.7 ± 4.2 and 12.2 ± 3.8 mmHg at 12 months, 11.9 ± 7.0 and 12.1 ± 3.1 mmHg at 36 months, and 13.0 ± 5.2 and 10.6 ± 1.2 mmHg at 120 months, respectively. The success rates (IOP 〈 18 mmHg, IOP reduction 〉 20%) in UG and POAG were 91.7% and 88.0% at 12 months, 82.2% and 75.6% at 36 months, and 66.5% and 61.8% at 120 months, respectively. The success rates (IOP 〈 15 mmHg) in UG and POAG were 64.0% and 58.0% at 12 months, 55.1% and 45.5% at 36 months, and 47.9% and 37.8% at 120 months, respectively. There was no significant difference in the success rate between UG and POAG at 120 months after surgery by either definition of surgical success. Conclusions. MMC-TLE effectively reduced IOP in both UG and POAG. There was no significant difference in the success rate between UG and POAG. Following sufficient inflammation suppression, surgical outcomes of UG may be comparable with those of POAG.
    Materialart: Online-Ressource
    ISSN: 2090-0058 , 2090-004X
    URL: Article
    DOI: 10.1155/2021/5550776
    Sprache: Englisch
    Verlag: Hindawi Limited
    Publikationsdatum: 2021
    ZDB Id: 2546525-9
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 8
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    Histological Findings in the Trabecular Meshwork of a Patient with Atopic Glaucoma
    Bentham Science Publishers Ltd. ; 2017
    In:  The Open Ophthalmology Journal Vol. 11, No. 1 ( 2017-05-29), p. 103-106
    Details
    In: The Open Ophthalmology Journal, Bentham Science Publishers Ltd., Vol. 11, No. 1 ( 2017-05-29), p. 103-106
    Kurzfassung: The aim of this study was to report a case of atopic dermatitis showing elevated intraocular pressure (IOP) beyond the baseline levels followed by a modified 360-degree suture trabeculotomy, and to analyze the histological findings in the trabecular meshwork. Methods: A 40-year-old male suffered from blurred vision in the right eye (OD). He had a medical history of severe atopic dermatitis and intraocular lens implantation OU due to atopic cataract. At the initial presentation, the visual acuity was 0.03, and IOP was 35 mmHg OD. Slit-lamp examination demonstrated corneal epithelial edema OD. Increased IOP was refractory to several topical medications. The patient underwent a modified 360-degree suture trabeculotomy. The visual field defect, however, deteriorated with persistently high IOP. The patient underwent trabeculectomy together with drainage implant surgery. In the outflow routes, although there seemed to be an opening of Schlemm’s canal into the anterior chamber, there was no endothelium of the canal in the region of its opening. The fibrotic changes were conspicuous around Schlemm’s canal. Conclusion: The histological results indicated that trabeculotomy might not be an appropriate treatment for patients with atopic glaucoma, possibly because of excessive repair to the newly created uveoscleral outflow in addition to the increased postoperative fibrosis in the trabecular meshwork and Schlemm’s canal.
    Materialart: Online-Ressource
    ISSN: 1874-3641
    URL: Article
    DOI: 10.2174/1874364101711010103
    Sprache: Englisch
    Verlag: Bentham Science Publishers Ltd.
    Publikationsdatum: 2017
    ZDB Id: 2395991-5
    Standort Signatur Einschränkungen Verfügbarkeit
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  • 9
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    Online-Ressource
    Histological analysis of trabeculotomy – An investigation on the intraocular pressure lowering mechanism
    Elsevier BV ; 2022
    In:  Experimental Eye Research Vol. 219 ( 2022-06), p. 109079-
    Details
    In: Experimental Eye Research, Elsevier BV, Vol. 219 ( 2022-06), p. 109079-
    Materialart: Online-Ressource
    ISSN: 0014-4835
    URL: Article
    DOI: 10.1016/j.exer.2022.109079
    RVK:
    XA 10000
    Sprache: Englisch
    Verlag: Elsevier BV
    Publikationsdatum: 2022
    ZDB Id: 1466924-9
    Standort Signatur Einschränkungen Verfügbarkeit
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