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  • 1
    Online Resource
    Online Resource
    Seasonal cruise Q4 2019 : Cruise Report
    UiT The Arctic University of Norway ; 2022
    In:  The Nansen Legacy Report Series , No. 36 ( 2022-10-31)
    Details
    In: The Nansen Legacy Report Series, UiT The Arctic University of Norway, , No. 36 ( 2022-10-31)
    Abstract: This cruise was the second of in total four seasonal cruises with RV Kronprins Haakon in 2019/20 focusing on biology in the project Arven etter Nansen (AeN). This seasonal cruise was named Q4 (Q4= 4th quarter of the year) investigating in total 17 stations of the established AeN transect along 34 E in the Northern Barents Sea and adjacent Arctic Basin from 76 to 82°N (see Fig. 1 below). The cruise addressed objectives of the research foci in RF1 on Physical drivers, RF2 on Human drivers, RF3 on the living Barents Sea and RA-C Technology and method development, and collected a multitude of data along the Nansen Legacy transect which was ice covered except the southernmost station P1. In addition to in situ sampling, on board experiments were conducted to quantify biological processes, rates and interactions that will also be important feeds into modeling work and projections in RF4 The future Barents Sea. The cruise took a variety of continuous ship measurements (Weather station, EK80, EM203, ADCP, thermosalinograph, pCO2 underway) as well as station measurements such as CTD with water samples, biological sampling of the benthos (box corer, benthic trawl), water column (multinet, MIK net, macrozooplankton trawl and many other smaller nets) and sea ice (snow, ice cores, water just underneath sea ice). In addition, experimental work (respiration, grazing and egg production) was conducted in the ship’s laboratories. The chemistry team onboard measured oxygen, nutrients and pH from standard depths on most CTD stations and sea ice samples. The cruise started in Longyearbyen and ended in Tromsø (28.11.-17.12.2019). The sampling began at the deep ( 〉 3000 m) northernmost station of the transect, Stn. P7, and continued along the southward transect until station P1, in open water and Atlantic dominated water masses. During the expedition the Barents Sea was characterized by a relatively large sea ice cover with consolidated sea ice all the way from P7 to P2. The Polar Front was located just north of P1. All process stations were sampled (P7-P1) as well as two ice stations: one close to P7 ad one close to P5. At the southernmost station P1, stormy weather challenged sampling, but most tasks were in the end accomplished except of deploying the box corer, sediment trap and the AUV. These operations were considered too challenging due to strong drift and ship movement, and it was not safe to conduct small boat operations. Challenges with the box corer was also experienced at the deep station P7 due to technical issues. In the end, most work was accomplished despite challenging weather, sea ice conditions and some technical issues making this cruise successful in gaining new important knowledge about the Northern Barents Sea in the polar night season which is extremely poorly studied. The overall high biological activity and biomass at this time of the year, November-December, was surprising for most of us.
    Type of Medium: Online Resource
    ISSN: 2703-7525
    URL: Issue
    URL: Article
    DOI: 10.7557/nlrs.2022.36
    DOI: 10.7557/nlrs.6750
    Language: Unknown
    Publisher: UiT The Arctic University of Norway
    Publication Date: 2022
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  • 2
    Online Resource
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    Synthesis of stereospecifically deuterated fluoroacetic acid and its behaviour in enzymic aldol‐type condensations
    Wiley ; 1980
    In:  FEBS Letters Vol. 114, No. 2 ( 1980-06-02), p. 287-290
    Details
    In: FEBS Letters, Wiley, Vol. 114, No. 2 ( 1980-06-02), p. 287-290
    Type of Medium: Online Resource
    ISSN: 0014-5793 , 1873-3468
    URL: Article
    DOI: 10.1016/0014-5793(80)81135-5
    RVK:
    WA 15000
    Language: English
    Publisher: Wiley
    Publication Date: 1980
    detail.hit.zdb_id: 1460391-3
    SSG: 12
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  • 3
    Online Resource
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    On atmospheric stability in the dynamic wake meandering model
    Wiley ; 2014
    In:  Wind Energy Vol. 17, No. 11 ( 2014-11), p. 1689-1710
    Details
    In: Wind Energy, Wiley, Vol. 17, No. 11 ( 2014-11), p. 1689-1710
    Abstract: The present study investigates a new approach for capturing the effects of atmospheric stability on wind turbine wake evolution and wake meandering by using the dynamic wake meandering model. The most notable impact of atmospheric stability on the wind is the changes in length and velocity scales of the atmospheric turbulence. The length and velocity scales in the turbulence are largely responsible for the way in which wind turbine wakes meander as they convect downstream. The hypothesis of the present work is that appropriate turbulence scales can be extracted from the oncoming atmospheric turbulence spectra and applied to the dynamic wake meandering model to capture the correct wake meandering behaviour. The ambient turbulence in all stability classes is generated using the Mann turbulence model, where the effects of non‐neutral atmospheric stability are approximated by the selection of input parameters. In order to isolate the effect of atmospheric stability, simulations of neutral and unstable atmospheric boundary layers using large‐eddy simulation are performed at the same streamwise turbulence intensity level. The turbulence intensity is kept constant by calibrating the surface roughness in the computational domain. The changes in the turbulent length scales due to the various atmospheric stability states impact the wake meandering characteristics and thus the power generation by the individual turbines. The proposed method is compared with results from both large‐eddy simulation coupled with an actuator line model and field measurements, where generally good agreement is found with respect to the velocity, turbulence intensity and power predictions. Copyright © 2013 John Wiley & Sons, Ltd.
    Type of Medium: Online Resource
    ISSN: 1095-4244 , 1099-1824
    URL: Issue
    URL: Article
    DOI: 10.1002/we.v17.11
    DOI: 10.1002/we.1662
    Language: English
    Publisher: Wiley
    Publication Date: 2014
    detail.hit.zdb_id: 2024840-4
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  • 4
    Online Resource
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    Implementation of a Mixing Length Turbulence Formulation Into the Dynamic Wake Meandering Model
    ASME International ; 2012
    In:  Journal of Solar Energy Engineering Vol. 134, No. 2 ( 2012-05-01)
    Details
    In: Journal of Solar Energy Engineering, ASME International, Vol. 134, No. 2 ( 2012-05-01)
    Abstract: The work presented in this paper focuses on improving the description of wake evolution due to turbulent mixing in the dynamic wake meandering (DWM) model. From wake investigations performed with high-fidelity actuator line simulations carried out in ELLIPSYS3D, it is seen that the current DWM description, where the eddy viscosity is assumed to be constant in each cross-section of the wake, is insufficient. Instead, a two-dimensional eddy viscosity formulation is proposed to model the shear layer generated turbulence in the wake, based on the classical mixing length model. The performance of the modified DWM model is verified by comparing the mean wake velocity distribution with a set of ELLIPSYS3D actuator line calculations. The standard error (defined as the standard deviation of the difference between the mean velocity field of the DWM and the actuator line model), in the wake region extending from 3 to 12 diameters behind the rotor, is reduced by 27% by using the new eddy viscosity formulation.
    Type of Medium: Online Resource
    ISSN: 0199-6231 , 1528-8986
    URL: Article
    DOI: 10.1115/1.4006038
    Language: English
    Publisher: ASME International
    Publication Date: 2012
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  • 5
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    Online Resource
    Multiple Pre- and Postreceptor Defects in Pseudohypoparathyroidism (A Multicenter Study with Twenty Four Patients)*
    The Endocrine Society ; 1986
    In:  The Journal of Clinical Endocrinology & Metabolism Vol. 62, No. 2 ( 1986-02), p. 393-402
    Details
    In: The Journal of Clinical Endocrinology & Metabolism, The Endocrine Society, Vol. 62, No. 2 ( 1986-02), p. 393-402
    Type of Medium: Online Resource
    ISSN: 0021-972X , 1945-7197
    URL: Article
    DOI: 10.1210/jcem-62-2-393
    RVK:
    XA 10000
    Language: English
    Publisher: The Endocrine Society
    Publication Date: 1986
    detail.hit.zdb_id: 2026217-6
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  • 6
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    Validation of uncertainty reduction by using multiple transfer locations for WRF–CFD coupling in numerical wind energy assessments
    Copernicus GmbH ; 2020
    In:  Wind Energy Science Vol. 5, No. 3 ( 2020-08-06), p. 997-1005
    Details
    In: Wind Energy Science, Copernicus GmbH, Vol. 5, No. 3 ( 2020-08-06), p. 997-1005
    Abstract: Abstract. This paper describes a method for reducing the uncertainty associated with utilizing fully numerical models for wind resource assessment in the early stages of project development. The presented method is based on a combination of numerical weather predictions (NWPs) and microscale downscaling using computational fluid dynamics (CFD) to predict the local wind resource. Numerical modelling is (at least) 2 orders of magnitude less expensive and time consuming compared to conventional measurements. As a consequence, using numerical methods could enable a wind project developer to evaluate a larger number of potential sites before making an investment. This would likely increase the chances of finding the best available projects. A technique is described, multiple transfer location analysis (MTLA), where several different locations for performing the data transfer between the NWP and the CFD model are evaluated. Independent CFD analyses are conducted for each evaluated data transfer location. As a result, MTLA will generate multiple independent observations of the data transfer between the NWP and the CFD model. This results in a reduced uncertainty in the data transfer, but more importantly MTLA will identify locations where the result of the data transfer deviates from the neighbouring locations. This will enable further investigation of the outliers and give the analyst a possibility to correct erroneous predictions. The second part is found to reduce the number and magnitude of large deviations in the numerical predictions relative to the reference measurements. The Modern Energy Wind Assessment Model (ME-WAM) with and without MTLA is validated against field measurements. The validation sample for ME-WAM without MTLA consists of 35 observations and gives a mean bias of −0.10 m s−1 and a SD of 0.44 m s−1. ME-WAM with MTLA is validated against a sample of 45 observations, and the mean bias is found to be +0.05 m s−1 with a SD of 0.26 m s−1. After adjusting for the composition of the two samples with regards to the number of sites in complex terrain, the reduction in variability achieved by MTLA is quantified to 11 % of the SD for non-complex sites and 35 % for complex sites.
    Type of Medium: Online Resource
    ISSN: 2366-7451
    URL: Article
    DOI: 10.5194/wes-5-997-2020
    Language: English
    Publisher: Copernicus GmbH
    Publication Date: 2020
    detail.hit.zdb_id: 2846783-8
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  • 7
    Online Resource
    Online Resource
    Integrational plasmids for the tetracycline-regulated expression of genes in Streptococcus pneumoniae
    Elsevier BV ; 1999
    In:  Gene Vol. 226, No. 2 ( 1999-1), p. 243-251
    Details
    In: Gene, Elsevier BV, Vol. 226, No. 2 ( 1999-1), p. 243-251
    Type of Medium: Online Resource
    ISSN: 0378-1119
    URL: Article
    DOI: 10.1016/S0378-1119(98)00561-7
    RVK:
    WA 15000
    Language: English
    Publisher: Elsevier BV
    Publication Date: 1999
    detail.hit.zdb_id: 1491012-3
    SSG: 12
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  • 8
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    Long-Term, Multicenter Results With the First Transcutaneous Bone Conduction Implant
    Ovid Technologies (Wolters Kluwer Health) ; 2021
    In:  Otology & Neurotology Vol. 42, No. 6 ( 2021-07), p. 858-866
    Details
    In: Otology & Neurotology, Ovid Technologies (Wolters Kluwer Health), Vol. 42, No. 6 ( 2021-07), p. 858-866
    Abstract: Investigation of long-term safety and performance of an active, transcutaneous bone conduction implant in adults and children up to 36 months post-implantation. Study Design: Prospective, single-subject repeated-measures design. Setting: Otolaryngology departments of eight German and Austrian hospitals. ∗†‡§||¶#∗∗†† Affiliations listed above that did not participate in the study. ‡‡§§||||¶¶ . Patients: Fifty seven German-speaking patients (49 adults and eight children) suffering from conductive or mixed hearing loss, with an upper bone conduction threshold limit of 45 dB HL at frequencies between 500 and 3000 Hz. Intervention: Implantation of the Bonebridge transcutaneous bone conduction hearing implant (tBCI). Main Outcome Measures: Patients’ audiometric pure tone averages (PTA 4 ) (0.5, 1, 2, 4 kHz) thresholds (air conduction, bone conduction, and sound field) and speech perception (word recognition scores [WRS] and speech reception thresholds [SRT50%] ) were tested preoperatively and up to 36 months postoperatively. Patients were also monitored for adverse events and administered quality-of-life questionnaires. Results: Speech perception (WRS: pre-op: 17.60%, initial activation [IA]: 74.23%, 3M: 83.65%, 12M: 83.46%, 24M: 84.23%, 36M: 84.42%; SRT50%: pre-op: 65.56 dB SPL, IA: 47.67 dB SPL, 3M: 42.61 dB SPL, 12M: 41.11 dB SPL, 24M: 41.74 dB SPL, 36M: 42.43 dB SPL) and sound field thresholds (pre-op: 57.66 dB HL, IA: 33.82 dB HL, 3M: 29.86 dB HL, 12M: 28.40 dB HL, 24M: 28.22 dB HL, 36M: 28.52 dB HL) improved significantly at all aided postoperative visits. Air and bone conduction thresholds showed no significant changes, confirming preservation of patients’ residual unaided hearing. All adverse events were resolved by the end of the study. Conclusions: Safety and performance of the tBCI was demonstrated in children and adults 36 months postoperatively.
    Type of Medium: Online Resource
    ISSN: 1531-7129 , 1537-4505
    URL: Article
    DOI: 10.1097/MAO.0000000000003159
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2021
    detail.hit.zdb_id: 2058738-7
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  • 9
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    ICAM-1/LFA-1 Expression in Acute Osteodestructive Joint Lesions in Collagen-induced Arthritis in Rats
    SAGE Publications ; 1997
    In:  Journal of Histochemistry & Cytochemistry Vol. 45, No. 9 ( 1997-09), p. 1247-1253
    Details
    In: Journal of Histochemistry & Cytochemistry, SAGE Publications, Vol. 45, No. 9 ( 1997-09), p. 1247-1253
    Abstract: Collagen-induced arthritis in rats is a widely used model of rheumatoid arthritis (RA). However, the joint immunohistopathology is less well characterized. The objective of this study was therefore to analyze whole ankle joints for markers known to mediate inflammatory mechanisms in RA. Indirect immunohistochemistry was performed on undecalcified cryostat sections for intercellular adhesion molecule-1 (ICAM-1, clone 1A 29) and leukocyte function-associated antigen-1 (LFA-1, clone WT.1) expression, for CD4 + lymphocytes (clone W3/25), B-cells (clone HIS 14), and macrophages (clone ED2). Acute, osteodestructive arthritis ( n = 8) induced with bovine collagen Type II was verified by clinical and radiological measures. LFA-1 expression was found almost exclusively at sites associated with cartilage erosion or osteodestruction. ICAM-1 was similarly expressed in the vicinity of tissue degradation but also by blood vessels in peripheral areas of joint swelling. CD4 + lymphocytes and macrophages were more ubiquitous. B-cells were infrequent. In control animals ( n = 4) ICAM-1 was expressed by synovial blood vessels. Macrophages were identified at the synovial lining. The results suggest that LFA-1 and ICAM-1 mediate important inflammatory events in this model. Similar findings in human RA synovium provide further arguments that collagen-induced arthritis in rats might be regarded as a comparable disease.
    Type of Medium: Online Resource
    ISSN: 0022-1554 , 1551-5044
    URL: Article
    DOI: 10.1177/002215549704500908
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1997
    detail.hit.zdb_id: 1421306-0
    SSG: 12
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  • 10
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    Activation of the NLRP3 Inflammasome by Hyaboron a New Asymmetric Boron-Containing Macrodiolide from the Myxobacterium Hyalangium minutum
    American Chemical Society (ACS) ; 2018
    In:  ACS Chemical Biology Vol. 13, No. 10 ( 2018-10-19), p. 2981-2988
    Details
    In: ACS Chemical Biology, American Chemical Society (ACS), Vol. 13, No. 10 ( 2018-10-19), p. 2981-2988
    Type of Medium: Online Resource
    ISSN: 1554-8929 , 1554-8937
    URL: Article
    URL: Article
    DOI: 10.1021/acschembio.8b00659
    DOI: 10.1021/acschembio.8b00659.s001
    Language: English
    Publisher: American Chemical Society (ACS)
    Publication Date: 2018
    detail.hit.zdb_id: 2221735-6
    SSG: 12
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