In:
FEBS Letters, Wiley, Vol. 298, No. 1 ( 1992-02-17), p. 21-24
Abstract:
Immunoreactive endothelin‐1 (ET‐1) and big‐endothelin‐1 (big‐ET‐1) were detected in conditioned medium of cultured rat pleural mesothelial cells by using sensitive sandwich‐type enzyme immunoassays. The amount of both ET‐1 and big‐ET‐1 increased time‐dependently. In both instances, maximal amount was detectable in conditioned medium obtained after 72 h in culture (ET‐1: 117.1 ± 30.1 pg/10 6 cells; big‐ET‐1: 2.4 ± 2.1 pg/10 6 cells). Fetal calf serum markedly stimulated the production of both ET‐1 and big‐ET‐1.
Type of Medium:
Online Resource
ISSN:
0014-5793
,
1873-3468
DOI:
10.1016/0014-5793(92)80013-7
Language:
English
Publisher:
Wiley
Publication Date:
1992
detail.hit.zdb_id:
1460391-3
SSG:
12
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