In:
Oncology & Hematology Review (US), Touch Medical Media, Ltd., Vol. 10, No. 01 ( 2014), p. 33-
Kurzfassung:
Breast cancer represents a common malignancy in the developed world. The treatment of breast cancer is multimodal, and includes surgical management, chemotherapy, radiation, and hormonal modulation. The selection and sequencing of the different facets of treatment are based on patient and tumor variables, including prognostic scores and desire for breast conservation or reconstruction. The role of irradiation of the breast in breast-conserving surgery is well established. Radiation of the chest wall post mastectomy has also been associated with survival benefit in patients with node-positive disease. Unlike several cancers for which preoperative chemoradiation is the standard of care, radiation is generally reserved as a final step in the treatment of breast cancer, and can delay reconstruction, as the presence of an autologous flap or an implant may reduce the capacity to deliver effective chest wall radiation. The question arises therefore, if neoadjuvant radiotherapy delivered after tumor chemosensitization, but in advance of definitive surgery, might offer an advantage over adjuvant radiotherapy.
Materialart:
Online-Ressource
ISSN:
2052-3815
DOI:
10.17925/OHR.2014.10.1.33
Sprache:
Englisch
Verlag:
Touch Medical Media, Ltd.
Publikationsdatum:
2014
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