In:
International Journal of Materials Research, Walter de Gruyter GmbH, Vol. 110, No. 5 ( 2019-05-15), p. 481-483
Abstract:
Cobalt-based nanoparticles are promising candidates towards countless biomedical applications due to their unique characteristics. Co 3 O 4 nanoparticles were synthesized by applying the sol-gel technique and finally sintered at various temperatures (700, 800, 900 °C). The crystal size, morphology, purity, and optical properties were determined using a variety of advanced characterization techniques. To investigate photodynamic therapy feasibility by using Co 3 O 4 nanoparticles in the liver cells, in-vitro cancerous liver cells (HepG2 cells) were exposed to light of wavelength 655 nm (red light) for 30 min at 50 mW cm −2 and in dark as well. After assessment of cell viability analysis, it is concluded that light-induced photodynamic therapy shows significant phototoxic effects based on temperature dependency.
Type of Medium:
Online Resource
ISSN:
2195-8556
,
1862-5282
Language:
Unknown
Publisher:
Walter de Gruyter GmbH
Publication Date:
2019
detail.hit.zdb_id:
2232675-3
detail.hit.zdb_id:
2128058-7
detail.hit.zdb_id:
203021-4
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