In:
Journal of the chemical society of pakistan, Chemical Society of Pakistan, Vol. 41, No. 6 ( 2019), p. 1097-1097
Abstract:
Synthesis of ethyl ester of acetic acid containing 5-oxo-[1,2,4] triazole ring (2) was achieved by the condensation of 3-substituted-4-amino-1H-1,2,4-triazol-5(4H)-one (1) with ethyl bromoacetate in basic medium. Compound 2, was then further reacted with hydrazine hydrate to form acid hydrazide, which is 2-(4-amino-3-substituted-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)acetohydrazide (3). Compound 3 was later treated with three different diverse coumarin aldehydes (6, 12, 18) resulted in the formation of arylidene hydrazides as cis–trans conformers (7, 8, 13, 14, 19, 20). In conclusion, we synthesized 1,2,4-triazole Schiff bases derived from the condensation of 3-substituted-4-amino-1,2,4-triazole-5-on and formylhydroxy-4-methylcoumarin derivatives, which have been characterized by, spectroscopic measurements (IR, 1H-NMR, 13C-NMR and elemental analysis).
Type of Medium:
Online Resource
ISSN:
0253-5106
Uniform Title:
Synthesıs and Characterızatıon of New Trıazole and Coumarın-Derived Heterocyclıc Compounds Part I
DOI:
10.52568/000830/JCSP/41.06.2019
Language:
Unknown
Publisher:
Chemical Society of Pakistan
Publication Date:
2019
detail.hit.zdb_id:
3024078-5
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