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  • 1
    Online Resource
    Online Resource
    ISOLATION OF 2-CHLOROBENZIMIDAZOLE FROM MELIA DUBIA LEAF EXTRACT AND ITS STRUCTURAL CHARACTERISATION
    Innovare Academic Sciences Pvt Ltd ; 2017
    In:  International Journal of Pharmacy and Pharmaceutical Sciences Vol. 9, No. 10 ( 2017-10-02), p. 67-
    Details
    In: International Journal of Pharmacy and Pharmaceutical Sciences, Innovare Academic Sciences Pvt Ltd, Vol. 9, No. 10 ( 2017-10-02), p. 67-
    Abstract: Objective: Natural products from medicinal plants, either as isolated compounds or as standardized plant extracts exhibit promising source of medicinal activity against various diseases. The aim of the present work was to make an attempt of isolation of bioactive principle and characterization of the isolated compound, from the medicinal plant Melia dubaiMethods: The extraction was done by a cold percolation method and the compound was separated and isolated by chromatography technique such as a thin layer chromatography (TLC), column chromatography and high-performance liquid chromatography (HPLC). The isolated compound was crystallized and the structural characterization of the isolated compound was made using UV-Visible, FT-IR, 1H-NMR, GC-MS and MS techniques which confirmed the structure of the isolated compound.Results: The separated and isolated compound was characterized by both physical and spectral methods like Ultraviolet-Visible spectroscopy (UV-Visible), Fourier transform infrared spectroscopy (FT-IR), Proton Nuclear Magnetic Resonance Spectroscopy (1H-NMR), Gas chromatography-mass spectrometry (GC-MS), and Mass spectrometry(MS). Based on the studies, organizational characteristics of one bioactive principle were deciphered. The results revealed that the isolated species is 2-chlorobenzimidazole and it agreed well with the reported value and spectra for 2-chlorobenzimidazole.Conclusion: The above results obtained in this research work clearly indicated the promising occurrence of 2-chlorobenzimidazole in Media dubia plant leaves. The future scope of these studies may guide us to view the biological activity of the isolated compound.
    Type of Medium: Online Resource
    ISSN: 0975-1491
    URL: Article
    DOI: 10.22159/ijpps.2017v9i10.20573
    Language: Unknown
    Publisher: Innovare Academic Sciences Pvt Ltd
    Publication Date: 2017
    detail.hit.zdb_id: 2503459-5
    SSG: 15,3
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  • 2
    Online Resource
    Online Resource
    Isolation and Characterisation of Flavonoids (Rutin) from the Roots of Cadaba aphylla (Thunb) and Adenia glauca of Potential in Anti-Oxidant activity
    Oriental Scientific Publishing Company ; 2022
    In:  Oriental Journal Of Chemistry Vol. 38, No. 6 ( 2022-12-30), p. 1404-1413
    Details
    In: Oriental Journal Of Chemistry, Oriental Scientific Publishing Company, Vol. 38, No. 6 ( 2022-12-30), p. 1404-1413
    Abstract: Natural medicine is widely used to treat a variety of ailments. This work aims to isolate and characterise flavonoids from the roots of Cadaba aphylla and Adenia glauca. The compound was extracted using the Ultrasonicate Assisted Extraction (UAE), and Chromatographic methods including thin layer chromatography (TLC) and column chromatography were then used to separate it. The isolated compound was then examined using UV-visible, FTIR, NMR (H1 & C13), and mass spectra (MS) followed by antioxidant evaluation. From the qualitative and spectral examination. The isolated component is identified as 3, 3', 4', 5, 7-pentahydroxy flavones-3-rutinoside, it is concluded (Rutin) and it also showed good free radical scavenging behaviour. Therefore, these plants can be used for therapeutic purpose.
    Type of Medium: Online Resource
    ISSN: 2231-5039 , 0970-020X
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.13005/ojc/3806
    DOI: 10.13005/ojc
    DOI: 10.13005/ojc/380610
    Language: English
    Publisher: Oriental Scientific Publishing Company
    Publication Date: 2022
    detail.hit.zdb_id: 2691868-7
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  • 3
    Online Resource
    Online Resource
    PHYTOCHEMICAL ANALYSIS IN ROOTS AND TUBERS OF BOTSWANA MEDICINAL PLANTS- Solanum Aculeastrum dunal, Elephantorrhiza elephentina, Cadaba aphylla (Thunb) AND Adenia glauca
    Rasayan Journal of Chemistry ; 2023
    In:  RASAYAN Journal of Chemistry Vol. 16, No. 01 ( 2023), p. 01-08
    Details
    In: RASAYAN Journal of Chemistry, Rasayan Journal of Chemistry, Vol. 16, No. 01 ( 2023), p. 01-08
    Abstract: Medicinal plants play an important role in our life. Worldwide modern drugs used in healthcare are derived from plants. Several Rhizomes and tubers are important for people due to their edible as well as medicinal properties. The Rhizome and tuberous plants namely Solanum aculeastrum dunal, Elephantorrhiza elephentina, Cadaba aphylla (Thunb), and Adenia glauca which are indigenous plants of Botswana have been so far employed in the treatment of cutaneous, subcutaneous parasitic infection, wounds, dermatological diseases, gastrointestinal system disorders, sexual dysfunction, and sexually transmitted infections. This study was conducted to identify the phytoconstituents by subjecting them to Ultrasound-Assisted Extraction (UAE) with distilled water, methanol, ethanol, chloroform, and hexane, each extract of which was further applied to the phytochemical screening through qualitative and quantitative tests. The extracting yields of Solanum aculeastrum dunal with different solvents gave the values of 13.0% (hexane), 13.0% (chloroform), 66.6% (ethanol), 66.6% (methanol) and 46.6% (aqueous), Elephantorrhiza elephentina 13.0% (hexane), 20.0% (chloroform), 66.6% (ethanol), 80.0% (methanol) and 86.0% (aqueous), Cadaba aphylla 60% (ethanol), 66.6% (methanol) and 53.3% (aqueous), Adenia glauca 40% (ethanol), 40.0% (methanol) and 46.6% (aqueous). Standards were used to determine the total content of alkaloid, flavonoid, phenol, saponin, and tannin (Atropine, Quercetin, Gallic acid, Tannic acid, and Quillaja). The regression coefficient (R2 ) was calculated and for Alkaloids, it is 0.9925, flavonoid (0.9953), phenol (0.9978), tannin (0.9955), and saponin (0.9912) respectively. These medicinal plants have produced many phytochemical substances in quantitative analysis, which will be applied in future drug analysis research
    Type of Medium: Online Resource
    ISSN: 0974-1496 , 0976-0083
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.31788/RJC.2023
    DOI: 10.31788/RJC
    DOI: 10.31788/RJC.2023.1618097
    Language: Unknown
    Publisher: Rasayan Journal of Chemistry
    Publication Date: 2023
    detail.hit.zdb_id: 2536963-5
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