In:
Asia-Pacific Psychiatry, Wiley, Vol. 13, No. 2 ( 2021-06)
Abstract:
A family history of psychiatric disorders is one of the strongest risk factors for schizophrenia. The characteristics of patients with a family history of psychiatric disorders have not been systematically evaluated. Methods This multicenter study (26 centers, 2425 cases) was performed in a Chinese population to examine the sociodemographic and clinical characteristics of schizophrenia patients with a family history of psychotic disorders in comparison with those of patients with sporadic schizophrenia. Results Nineteen percent of patients had a family history of mental disease. Multiple logistic regression analysis revealed that ≥4 hospitalizations (OR = 1.78, P = .004), tobacco dependence (OR = 1.48, P = .006), alcohol dependence (OR = 1.74, P = .013), and physical illness (OR = 1.89, P = .001) were independently and significantly associated with a family history of mental disease. Conclusion Patients with a family history of mental disorders present different demographics and clinical features than patients without a family history of psychiatric disorders.
Type of Medium:
Online Resource
ISSN:
1758-5864
,
1758-5872
Language:
English
Publisher:
Wiley
Publication Date:
2021
detail.hit.zdb_id:
2506343-1
Permalink