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  • 1
    Online Resource
    Online Resource
    Frontiers Media SA ; 2022
    In:  Frontiers in Nutrition Vol. 9 ( 2022-11-18)
    In: Frontiers in Nutrition, Frontiers Media SA, Vol. 9 ( 2022-11-18)
    Abstract: The prospective association between plasma Se and stroke risk remains inconclusive. The relationship between Se and ischemic stroke among a low circulating Se status population deserves more attention, especially for Chinese people who were a high-risk group for Se deficiency. Objective The relationship between plasma Se concentration and ischemic stroke risk in a large-scale Chinese community-based population and any potential effect modifiers were investigated. Methods A nested, case-control study, using data from the “China H-type Hypertension Registry Study” were conducted. A total of 1,904 first ischemic stroke cases and 1,904 controls matched for age, sex, and village were included in this study. The association between plasma Se and first ischemic stroke was evaluated by conditional logistic regression analyses. Results The median value of plasma Se was 65.8 μg/L among total participants. Overall, a significant inverse relationship between plasma Se and first ischemic stroke risk was found (per SD increment; adjusted OR: 0.87; 95% CI: 0.80 and 0.95). Accordingly, a significantly lower risk of first ischemic stroke was found in participants in quartile 3 (65.8− & lt;77.8 μg/L) (adjusted OR: 0.78; 95% CI: 0.63 and 0.96) and quartile 4 (≥77.8 μg/L) (adjusted OR: 0.76; 95% CI: 0.59 and 0.96), compared with those in quartile 1 ( & lt;56.0 μg/L). Furthermore, a significantly lower ischemic stroke risk was found in those with lower low-density lipoprotein cholesterol (LDL-C) levels ( & lt;3.4 vs. ≥3.4 mmol/L; P for interaction = 0.015) or those with lower homocysteine levels ( & lt;12.1 (median) vs. ≥12.1 μmol/L; P for interaction = 0.027) at baseline. Conclusion Plasma Se was significantly inversely associated with the risk of first ischemic stroke among a large-scale Chinese community-based population (most adults with hypertension and elevated total homocysteine), especially among those with lower LDL-C and lower homocysteine levels.
    Type of Medium: Online Resource
    ISSN: 2296-861X
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2776676-7
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  • 2
    In: Biodiversity Science, Biodiversity Science, Vol. 23, No. 3 ( 2015), p. 321-331
    Type of Medium: Online Resource
    ISSN: 1005-0094
    Language: English
    Publisher: Biodiversity Science
    Publication Date: 2015
    detail.hit.zdb_id: 2232800-2
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  • 3
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2012
    In:  Climate Dynamics Vol. 38, No. 9-10 ( 2012-5), p. 2017-2035
    In: Climate Dynamics, Springer Science and Business Media LLC, Vol. 38, No. 9-10 ( 2012-5), p. 2017-2035
    Type of Medium: Online Resource
    ISSN: 0930-7575 , 1432-0894
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2012
    detail.hit.zdb_id: 382992-3
    detail.hit.zdb_id: 1471747-5
    SSG: 16,13
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  • 4
    Online Resource
    Online Resource
    American Geophysical Union (AGU) ; 2023
    In:  Journal of Geophysical Research: Oceans Vol. 128, No. 3 ( 2023-03)
    In: Journal of Geophysical Research: Oceans, American Geophysical Union (AGU), Vol. 128, No. 3 ( 2023-03)
    Abstract: Frequency and phase decompositions of near‐equatorial zonal currents show the seasonal latitudinal boundaries of WJs, MC, and SECC along 80.5°E Meridional‐width variability of the near‐equatorial zonal currents shows an asymmetric response to strong pIOD and nIOD on interannual timescales Underlying mechanisms are related to spatial differences in large‐scale wind anomalies associated with wind/eastern‐boundary generated waves
    Type of Medium: Online Resource
    ISSN: 2169-9275 , 2169-9291
    Language: English
    Publisher: American Geophysical Union (AGU)
    Publication Date: 2023
    detail.hit.zdb_id: 2016804-4
    detail.hit.zdb_id: 161667-5
    detail.hit.zdb_id: 3094219-6
    SSG: 16,13
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  • 5
    Online Resource
    Online Resource
    American Meteorological Society ; 2020
    In:  Journal of Climate Vol. 33, No. 13 ( 2020-07-01), p. 5547-5564
    In: Journal of Climate, American Meteorological Society, Vol. 33, No. 13 ( 2020-07-01), p. 5547-5564
    Abstract: Based on observational data, this work examines the multi-time-scale feature of the sea surface temperature (SST) variability averaged in the whole North Atlantic Ocean (to be referred to as NASST), as well as its time-scale-dependent connections with El Niño–Southern Oscillation (ENSO) and the North Atlantic Oscillation (NAO). Traditionally, the NASST index is used to characterize the SST trend and multidecadal variability in the North Atlantic. This study found that superimposed on a prominent long-term trend, NASST is nonnegligible at subannual and interannual time scales, compared with that at decadal to multidecadal time scales. Spatially, the interannual variation of NASST is characterized by a horseshoe-like pattern of the SST anomaly (SSTA) in the North Atlantic. It is mainly a lagged response to ENSO through the atmospheric bridge, and NAO plays a secondary role. At the subannual time scale, both ENSO and NAO play a role in generating the fluctuations of NASST and a horseshoe-like pattern in the North Atlantic. Nevertheless, both the ENSO- and NAO-driven variations only explain a small fraction of the variances in both the interannual and subannual time scales. Thus, other factors unrelated to ENSO or NAO may play a more important role. The associated thermodynamical processes are similar at the two time scales; however, the dynamical processes have a significant contribution to the subannual component, but not to the interannual component. Thus, the SSTA averaged in the North Atlantic as a whole varies at different time scales and is associated with different mechanisms.
    Type of Medium: Online Resource
    ISSN: 0894-8755 , 1520-0442
    RVK:
    Language: Unknown
    Publisher: American Meteorological Society
    Publication Date: 2020
    detail.hit.zdb_id: 246750-1
    detail.hit.zdb_id: 2021723-7
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  • 6
    In: Stroke, Ovid Technologies (Wolters Kluwer Health), Vol. 43, No. 3 ( 2012-03), p. 838-843
    Abstract: Netrin-1 (NT-1) stimulates endothelial cell proliferation and migration in vitro and promotes focal neovascularization in the adult brain in vivo. This in vivo study in mice investigated the effect of NT-1 hyperexpression on focal angiogenesis and long-term functional outcome after transient middle cerebral artery occlusion (tMCAO). Methods— Adeno-associated viral vectors carrying either the NT-1 gene (AAV–NT-1) or GFP (AAV-GFP) were generated and injected into the brains of separate groups of 93 mice. Seven days later, tMCAO followed by 7–28 days of reperfusion were carried out. Histological outcomes and behavioral deficits were quantified 7–28 days after tMCAO. Small cerebral vessel network and angiogenesis were assessed 28 days after tMCAO, using synchrotron radiation microangiography and immunohistochemistry. Results— Western blot and immunohistochemistry showed that on the day of tMCAO, NT-1 hyperexpression had been achieved in both normal and ischemic hemispheres. Immunofluorescence imaging showed that NT-1 expression was primarily in neurons and astrocytes. Ischemia-induced infarction in the NT-1 hyperexpression group was attenuated in comparison to saline or AAV-GFP–treated groups ( P 〈 0.01). Similarly, neurological deficits were greatly improved in AAV–NT-1–treated mice compared with mice in saline or AAV-GFP–treated groups ( P 〈 0.05). In addition, angiogenesis was increased in AAV–NT-1–treated mice compared with the other 2 groups ( P 〈 0.05). In vivo synchrotron radiation microangiography 28 days after tMCAO revealed more branches in AAV–NT-1–treated mice than in other groups. Conclusions— AAV–NT-1 induced NT-1 hyperexpression before tMCAO reduced infarct size, enhanced neovascularization, and improved long-term functional recovery.
    Type of Medium: Online Resource
    ISSN: 0039-2499 , 1524-4628
    RVK:
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2012
    detail.hit.zdb_id: 1467823-8
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  • 7
    Online Resource
    Online Resource
    American Meteorological Society ; 2013
    In:  Journal of the Atmospheric Sciences Vol. 70, No. 1 ( 2013-01-01), p. 303-316
    In: Journal of the Atmospheric Sciences, American Meteorological Society, Vol. 70, No. 1 ( 2013-01-01), p. 303-316
    Abstract: The presence of the latitudinal variation of the Coriolis parameter serves as a mechanical barrier that causes a mass convergence for the poleward geostrophic flow and divergence for the equatorward flow, just as a sloped bottom terrain does to a crossover flow. Part of the mass convergence causes pressure to rise along the uphill pathway, while the remaining part is detoured to cross isobars out of the pathway. This mechanically excited cross-isobar flow, being unbalanced geostrophically, is subject to a “half-cycle” Coriolis force that only turns it to the direction parallel to isobars without continuing to turn it farther back to its opposite direction because the geostrophic balance is reestablished once the flow becomes parallel to isobars. Such oscillation, involving a barrier-induced mass convergence, a mechanical deflection, and a half-cycle Coriolis deflection, is referred to as a mechanical–Coriolis oscillation with a “barrier-induced half-cycle Coriolis force” as its restoring force. Through a complete cycle of the mechanical–Coriolis oscillation, a new geostrophically balanced flow pattern emerges to the left of the existing flow when facing the uphill (downhill) direction of the barrier in the Northern (Southern) Hemisphere. The β barrier is always sloped toward the pole in both hemispheres, responsible for the westward propagation of Rossby waves. The β-induced mechanical–Coriolis oscillation frequency can be succinctly expressed as , where , and λ is the angle of a sloped surface along which the unbalanced flow crosses isobars, α is the angle of isobars with the barrier’s slope, and k is the wavenumber along the direction of the barrier’s contours.
    Type of Medium: Online Resource
    ISSN: 0022-4928 , 1520-0469
    RVK:
    Language: English
    Publisher: American Meteorological Society
    Publication Date: 2013
    detail.hit.zdb_id: 218351-1
    detail.hit.zdb_id: 2025890-2
    SSG: 16,13
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  • 8
    Online Resource
    Online Resource
    American Meteorological Society ; 2013
    In:  Journal of Climate Vol. 26, No. 13 ( 2013-07-01), p. 4649-4663
    In: Journal of Climate, American Meteorological Society, Vol. 26, No. 13 ( 2013-07-01), p. 4649-4663
    Abstract: In this work, the authors analyze the physical mechanisms of interannual variability of the upper-ocean temperature anomaly (OTA) in the equatorial Atlantic Ocean, using ocean reanalysis from the National Centers for Environmental Prediction (NCEP) Global Ocean Data Assimilation System. The variability of equatorial Atlantic OTA is dominated by two leading modes. The first mode is characterized by same-sign variation along the thermocline with pronounced amplitude in the central and eastern equatorial Atlantic. This mode represents the modulation of the overall thermocline depth at the equator generated by net heat convergence in the equatorial ocean, with heat content first accumulated mainly in the off-equatorial northwestern Atlantic in response to anomalous wind curl associated with Atlantic meridional mode. The second leading mode shows an opposite variation between the western and eastern Atlantic. This mode is mainly driven by the zonal wind stress fluctuation confined in the southwestern tropical and equatorial Atlantic and reflects the equatorial balanced response between the zonal slope of the equatorial thermocline depth and the atmospheric zonal wind variations with pronounced surface wind and ocean anomalies in the southwestern and equatorial ocean. The different characteristics of these two modes suggest that they may occur independently. In fact, evolution of the two leading modes is approximately in quadrature, and they may also occur in sequence on interannual time scales. The two leading mode-associated air–sea interaction processes suggest that the Atlantic meridional mode and zonal mode are statistically and physically connected in their evolution.
    Type of Medium: Online Resource
    ISSN: 0894-8755 , 1520-0442
    RVK:
    Language: English
    Publisher: American Meteorological Society
    Publication Date: 2013
    detail.hit.zdb_id: 246750-1
    detail.hit.zdb_id: 2021723-7
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  • 9
    Online Resource
    Online Resource
    American Meteorological Society ; 2006
    In:  Journal of Climate Vol. 19, No. 21 ( 2006-11-01), p. 5700-5708
    In: Journal of Climate, American Meteorological Society, Vol. 19, No. 21 ( 2006-11-01), p. 5700-5708
    Abstract: Different measures of wind influence the ocean in different ways. In particular, the time-averaged mixed layer turbulent energy production rate is proportional to 〈u3*〉, where u* is the “oceanic friction velocity” that is based on wind stress. Estimating 〈u3*〉 from monthly averages of wind stress or wind speed may introduce large biases due to the day-to-day variability of the direction and magnitude of the wind. The authors create monthly climatologies of 〈u3*〉 from daily wind stress measurements obtained from the Goddard Satellite-based Surface Turbulent Fluxes version 2 (GSSTF2; based on satellite microwave measurements), the Quick Scatterometer (QuikSCAT; based on satellite scatterometry measurements), and the National Centers for Environmental Prediction (NCEP) reanalysis wind. The differences among zonal averages of these climatologies and of a similar climatology based on the da Silva version of the Comprehensive Ocean–Atmosphere Data Set (COADS) have a complex dependence on latitude. These differences are typically 10%–30% of the climatological values. The GSSTF2 data confirm that 〈u3*〉 is much larger than estimates from monthly averaged wind stress or wind speed, especially outside the Tropics.
    Type of Medium: Online Resource
    ISSN: 1520-0442 , 0894-8755
    RVK:
    Language: English
    Publisher: American Meteorological Society
    Publication Date: 2006
    detail.hit.zdb_id: 246750-1
    detail.hit.zdb_id: 2021723-7
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  • 10
    Online Resource
    Online Resource
    American Meteorological Society ; 2012
    In:  Journal of Climate Vol. 25, No. 7 ( 2012-04-01), p. 2490-2508
    In: Journal of Climate, American Meteorological Society, Vol. 25, No. 7 ( 2012-04-01), p. 2490-2508
    Abstract: The observed negative correlation between El Niño–Southern Oscillation (ENSO) and the Indian summer monsoon is not simulated by the National Centers for Environmental Prediction (NCEP) Climate Forecast System (CFS) coupled model. The correlation is partially restored in the simulations where the Indian Ocean (IO) sea surface temperature (SST) is prescribed with the daily mean or climatology. Comparison among the simulations suggests that ENSO-induced SST anomalies form a strong dipole pattern oriented along the zonal direction in the IO in the coupled model, preventing the ENSO signals from reaching the Indian monsoon region. In the model, the dipole develops early in the monsoon season and extends to the central equatorial IO while it is formed at the end of the season in observations. The dipole modifies low-level winds and surface pressure, and grows in a positive feedback loop involving winds, surface pressure, and SST. Examination of the mean state in the model reveals that the thermocline is relatively shallow in the eastern IO. This preconditions the ocean such that the atmospheric fluxes can easily impart fluctuations in the subsurface temperature and thereby in the SST. These results suggest that biases in the IO can adversely affect the ENSO–monsoon teleconnection in a coupled model.
    Type of Medium: Online Resource
    ISSN: 0894-8755 , 1520-0442
    RVK:
    Language: English
    Publisher: American Meteorological Society
    Publication Date: 2012
    detail.hit.zdb_id: 246750-1
    detail.hit.zdb_id: 2021723-7
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