In:
The Journal of Immunology, The American Association of Immunologists, Vol. 178, No. 1_Supplement ( 2007-04-01), p. LB45-LB45
Abstract:
This study has examined the effects of 204 herbs, which are used in Traditional Korean Medicine, on the immune system. After the separation of splenocytes of BALB/c mice, two concentrations (1 §¶/§¢, 10 §¶/§¢) of herb medicine were given, and then the inducement of IL-4 was examined and measured using a sandwich ELISA. The amount of IL-4 each herb induced was analyzed, and the herb medicines were classified using two methods. One was the classification method of Traditional Korean Medicine, and the other was according to botanical phylogenetic systematics. There were significant results for the analysis according to the botanical phylogenetic classification (Order). When there was a low concentration of the herb medicines, IL-4 was decreased by Ranunculales and Rosales, and increased by Malvales. When there was a high concentration of the herb medicines, IL-4 was decreased by Liliales, Ranunculales, Asterales, Fabales, Lamiales, Rosales, and Rutlaes, and increased by Malvales. The results showed the characteristics of individual herb medicines that have an affect on the inducement of IL-4 in splenocytes of a BALB/c mouse. In relation to the immune system, there was significant meaning to the functions of drugs for dispersing actions of wind and cold, drugs for dispersing actions of wind and heat, drugs for reducing intense internal heat, and drugs for eliminating heat and dampness, and also classifying the herb medicines according to botanical phylogenetics (Order). This work was supported by the Brain Korea 21 project in 2007
Type of Medium:
Online Resource
ISSN:
0022-1767
,
1550-6606
DOI:
10.4049/jimmunol.178.Supp.B216
Language:
English
Publisher:
The American Association of Immunologists
Publication Date:
2007
detail.hit.zdb_id:
1475085-5
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