In:
Journal of Investigative Medicine, SAGE Publications, Vol. 66, No. 8 ( 2018-12), p. 1083-1087
Abstract:
Patients with glioblastoma multiforme (GBM) have an average life expectancy of approximately 15 months. Recently, statins have emerged as a potential adjuvant cancer therapy due to their ability to inhibit cell proliferation and induce apoptosis in many types of cancer. The exact mechanisms that mediate the inhibitory actions of statins in cancer cells are largely unknown. The purpose of this proceeding paper is to discuss some of the known anticancer effects of statins, while focusing on GBM therapy that includes adjunct therapy of statins with chemotherapeutic agents.
Type of Medium:
Online Resource
ISSN:
1081-5589
,
1708-8267
DOI:
10.1136/jim-2018-000874
Language:
English
Publisher:
SAGE Publications
Publication Date:
2018
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