In:
Artificial Organs, Wiley, Vol. 38, No. 7 ( 2014-07), p. 598-603
Abstract:
It has been speculated that testosterone stimulates erythropoiesis. We hypothesized that hemoglobin levels in hemodialysis ( HD ) patients are associated with serum testosterone concentrations. Testosterone, hemoglobin, and other biochemical parameters were measured in a representative sample of 98 chronic HD patients (50 male, 48 female; age 30–90 years, mean 65 ± 13.9 years). We investigated relations among serum testosterone concentration, hemoglobin, ferritin, albumin, body mass index, lean body mass, total cholesterol, low‐density lipoprotein and high‐density lipoprotein cholesterol, triglycerides, high‐sensitivity C‐reactive protein ( hsCRP ), calcium ( C a), P , intact parathyroid hormone, N‐terminal pro‐brain natriuretic peptide, K arnofsky performance status, and blood pressure ( BP ) before and after HD . A statistically significant positive correlation between testosterone and hemoglobin was found in all patients ( r = 0.25, P 〈 0.01), men ( r = 0.34, P 〈 0.02), but not in women ( r = 0.27, P = 0.07). Multiple regression analysis for all patients has shown statistically significant association between hemoglobin and testosterone ( P 〈 0.001), hsCRP ( P 〈 0.005), lean body mass ( P 〈 0.05), post‐ HD systolic ( P 〈 0.04), and diastolic BP ( P 〈 0.005). Multiple regression analysis in men has shown an association between hemoglobin and testosterone ( P 〈 0.04) and post‐ HD diastolic BP ( P 〈 0.04) and in women association between hemoglobin and testosterone ( P 〈 0.04), C a ( P 〈 0.03), and post‐ HD diastolic BP ( P 〈 0.03). We found an association between serum testosterone concentration and hemoglobin in male and female HD patients.
Type of Medium:
Online Resource
ISSN:
0160-564X
,
1525-1594
DOI:
10.1111/aor.2014.38.issue-7
Language:
English
Publisher:
Wiley
Publication Date:
2014
detail.hit.zdb_id:
441812-8
detail.hit.zdb_id:
2003825-2
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