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  • 1
    Online Resource
    Online Resource
    Elsevier BV ; 2015
    In:  The Spine Journal Vol. 15, No. 2 ( 2015-02), p. 365-366
    In: The Spine Journal, Elsevier BV, Vol. 15, No. 2 ( 2015-02), p. 365-366
    Type of Medium: Online Resource
    ISSN: 1529-9430
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2015
    detail.hit.zdb_id: 2057875-1
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  • 2
    Online Resource
    Online Resource
    Wiley ; 1974
    In:  Journal of Oral Rehabilitation Vol. 1, No. 2 ( 1974-04), p. 171-181
    In: Journal of Oral Rehabilitation, Wiley, Vol. 1, No. 2 ( 1974-04), p. 171-181
    Type of Medium: Online Resource
    ISSN: 0305-182X , 1365-2842
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 1974
    detail.hit.zdb_id: 2007587-X
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  • 3
    Online Resource
    Online Resource
    SAGE Publications ; 2019
    In:  Foot & Ankle Orthopaedics Vol. 4, No. 4 ( 2019-10-01), p. 2473011419S0025-
    In: Foot & Ankle Orthopaedics, SAGE Publications, Vol. 4, No. 4 ( 2019-10-01), p. 2473011419S0025-
    Abstract: Ankle Arthritis, Hindfoot Introduction/Purpose: Triple arthrodesis is a commonly performed surgical treatment for hindfoot arthritis and deformity. No study has clearly delineated correlates of both clinical and radiographic outcomes in a sample size this large. The purpose of this study is to explore predictive and demographic outcome measures with long-term followup after triple arthrodesis. Methods: With IRB approval, an institutional radiology database was queried for patients undergoing triple arthrodesis between 2004 and 2016, by a single surgeon at a single institution. A total of 465 cases were identified. Pre- and post-operative clinical and radiographic data was collected retrospectively. Demographic and predictive data included: age, Body Mass Index (BMI), American Society of Anesthesiologists Score (ASA), Charleston Comorbidity Index (CCI), diabetic status, osteoporosis, hypothyroidism, and neuromuscular disease status. Clinical outcomes including infection rate, reoperation rate and clinical nonunion were recorded. Unintended return to the operating room defined clinical failure. Radiographic data including non-union rate, pre- and post- operative ankle degenerative joint disease was also recorded. Statistical analysis was then performed to evaluate the relationship between predictive measures and various outcomes including reoperation, infection, and non-union rates. 23 cases were lost to follow-up. Results: A total of 442 feet (397 patients) were analyzed. The average age was 54 years (14 to 85) with the majority of cases being female (60%). Average follow up was 593 days (40 to 4079). Overall failure rate was 13.7% with clinical nonunion rate of 4.5%. Infection rate was 5.9%. Mortality rate was 0% at 2 years post-operatively. Predictors of failure included: increased BMI, elevated ASA, history of diabetes, underlying neuromuscular disorder (Figure 1). We found no significant difference between pre and post-operative degenerative joint disease rates in the midfoot (9.4%, 12.5%) and ankle (11.7%,13.7%), respectively. Conclusion: Triple arthrodesis is a highly effective procedure for treating hindfoot arthritis. Certain predictive measures including BMI, ASA score, diabetic status and underlying neuromuscular disorders significantly correlate with radiographic union. Additionally, diabetic status significantly correlates with infection status postoperatively. An understanding of these predictive measures may help surgeons in their preoperative planning to improve their clinical and radiographic success rates.
    Type of Medium: Online Resource
    ISSN: 2473-0114 , 2473-0114
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2874570-X
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  • 4
    Online Resource
    Online Resource
    SAGE Publications ; 2019
    In:  Foot & Ankle Orthopaedics Vol. 4, No. 4 ( 2019-10-01), p. 2473011419S0003-
    In: Foot & Ankle Orthopaedics, SAGE Publications, Vol. 4, No. 4 ( 2019-10-01), p. 2473011419S0003-
    Abstract: Regional anesthesia for foot and ankle surgery Introduction/Purpose: Regional anesthesia has resulted in significant improvements in patient outcomes including reduced postoperative pain, opioid consumption, opioid-related adverse effects, and decreased postoperative length of stay. Saphenous nerve blocks provide distal analgesia while minimizing the reduction in quadriceps strength seen with more proximal femoral nerve blocks. Saphenous nerve blocks may be performed at the mid-thigh with the subsartorial technique or just proximal to the knee with the transsartorial technique. The present study compares these two techniques in terms of analgesia effectiveness and quadriceps motor preservation. Methods: This study was approved by our institutional IRB committee. A power analysis was conducted prior to the study. Patients, aged 18 to 65, were prospectively identified from a list of elective foot and ankle surgeries performed by one of the study investigators. Preoperatively, bilateral isometric knee extension strength was measured, and subjects completed a PROMIS global health survey. The surgeon was blinded to the randomization of patients to proximal or distal blocks. Bilateral isometric knee extension strength was reassessed following the block as well as sensation, post-operative visual analogue pain score (VAS), and subjective satisfaction. Due to non-normality of the sample, the Wilcoxon rank-sum test was employed to analyze continuous variables such as strength measures. For categorical variables such as gender, pain score, and patient satisfaction, the Pearson chi- square test was used. Results: Twenty-four patients (24 lower extremities) were enrolled in the study and 12 randomized to each group. The two groups were not significantly different in age, gender, or pre-operative PROMIS Mental and Physical Summary Scores. The nerve block procedure was successfully performed in a single attempt in all cases. The VAS was not significantly different at 2 in the distal group and 3 in the proximal group. In each group 11 patients were totally satisfied with the block and 1 was moderately satisfied. The knee extension strength decreased in both the operative and non-operative lower extremity following administration of the nerve block. When normalized to the effect in the non-operative extremity, there was no significant difference in strength decrease between the two groups (p=0.89). Conclusion: This randomized, single-blinded trial compared proximal subsartorial saphenous nerve block with distal transsartorial saphenous nerve block outside of the adductor canal. There was no significant difference in the efficacy of the two techniques was observed in terms of VAS pain score or patient satisfaction and no difference in post-operative weakness. This is the first randomized trial on saphenous nerve blocks to normalize strength to the non-operative lower extremity, reducing the confounding effect of peri-operative narcotic and sedative medications. This study offers evidence for equivalence of the subsartorial and transsartorial saphenous nerve block techniques.
    Type of Medium: Online Resource
    ISSN: 2473-0114 , 2473-0114
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
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  • 5
    Online Resource
    Online Resource
    SAGE Publications ; 2019
    In:  Foot & Ankle Orthopaedics Vol. 4, No. 4 ( 2019-10-01), p. 2473011419S0020-
    In: Foot & Ankle Orthopaedics, SAGE Publications, Vol. 4, No. 4 ( 2019-10-01), p. 2473011419S0020-
    Abstract: Trauma Introduction/Purpose: The lateral calcaneal artery provides critical arterial supply for healing of the extensile lateral approach to the calcaneus. A recent study has shown that preoperative doppler ultrasound showing non-patency of the lateral calcaneal artery is strongly correlated with wound complications when using this approach. Plate and screw fixation of calcaneus fractures through the sinus tarsi approach has gained popularity, including techniques involving percutaneous screw placement into a plate. Avoidance of lateral calcaneal artery injury may be improved with further quantification of its anatomy and associated variation. Finally, while the lateral approach to the calcaneus for osteotomy is routinely performed with minimal wound complications, the relationship of the lateral calcaneal artery to this approach was studied as well. Methods: This is a cadaveric anatomic study performed using six fresh frozen cadaver specimens. The specimens were treated with intra-arterial injection of latex and dye. The specimens were first utilized in a separate study in which an orthopedic resident, blinded to the present study, performed a standard, oblique osteotomy of the calcaneal body. The cadavers were then examined for the relationship of the lateral calcaneal artery to the previous dissections. Finally, an extended sinus tarsi approach was made, and the relationship of the lateral calcaneal artery was quantified relative to the posterior facet and the posterior most point of the tuberosity, and relative to screw holes in a percutaneous calcaneal plate. Results: Lateral calcaneal artery injury was observed in six out of six cadavers in which calcaneal osteotomy had been performed. The lateral calcaneal artery was encountered when performing the extended sinus tarsi approach at a mean ratio of 0.4 (standard deviation 0.11) of the distance from the posterior facet to the posterior aspect of the tuberosity. It crossed the posterior-most hole in the posterior facet portion of the plate in two cadavers. It also passed within 2 mm of the posterior most hole in the tuberosity portion of the plate in one cadaver. Conclusion: Careful dissection is warranted when extending the sinus tarsi approach beyond the posterior facet to preserve the lateral calcaneal artery. Injury is also possible with percutaneous tuberosity screw placement into a plate, and the consequences for sinus tarsi approach healing are unknown. Lateral calcaneal artery injury is difficult to avoid with the traditional lateral approach for calcaneal osteotomy, and while it has no implications for that approach which heals reliably, it indicates that preoperative doppler would be warranted if extensile lateral approach were considered in a patient who has previously undergone calcaneal osteotomy.
    Type of Medium: Online Resource
    ISSN: 2473-0114 , 2473-0114
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2874570-X
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  • 6
    Online Resource
    Online Resource
    Wiley ; 2010
    In:  Pacing and Clinical Electrophysiology Vol. 33, No. 6 ( 2010-02-01), p. 721-726
    In: Pacing and Clinical Electrophysiology, Wiley, Vol. 33, No. 6 ( 2010-02-01), p. 721-726
    Type of Medium: Online Resource
    ISSN: 0147-8389 , 1540-8159
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2010
    detail.hit.zdb_id: 2037547-5
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  • 7
    In: Quarterly Journal of Speech, Informa UK Limited, Vol. 29, No. 3 ( 1943-10), p. 365-379
    Type of Medium: Online Resource
    ISSN: 0033-5630 , 1479-5779
    RVK:
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 1943
    detail.hit.zdb_id: 2066946-X
    SSG: 7,11
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  • 8
    Online Resource
    Online Resource
    Royal Society of Chemistry (RSC) ; 2009
    In:  Soft Matter Vol. 5, No. 6 ( 2009), p. 1228-
    In: Soft Matter, Royal Society of Chemistry (RSC), Vol. 5, No. 6 ( 2009), p. 1228-
    Type of Medium: Online Resource
    ISSN: 1744-683X , 1744-6848
    Language: English
    Publisher: Royal Society of Chemistry (RSC)
    Publication Date: 2009
    detail.hit.zdb_id: 2191476-X
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  • 9
    In: Journal of Orthopaedic Research, Wiley, Vol. 37, No. 6 ( 2019-06), p. 1451-1459
    Abstract: Tissue engineering approaches to treatment of intervertebral disc degeneration (IDD) represent a novel avenue of addressing the biologic basis of this disease. However, such approaches remain limited by their invasive nature and disruption to the annular fibrosis (AF). This study sought to explore a new minimally‐invasive tissue‐engineering approach utilizing an injection of a photopolymerizable biogel scaffold seeded with mesenchymal stem cells (MSCs) directly into the nucleus pulposus (NP). This study was performed using rabbit specimens for both in vivo and in vitro outcome measures. The treatment in this study was performed by injecting 25 μl of 10% (w/v) methacrylated gelatin biogel with 0.15% (w/v) lithium phenyl 2,4,6‐trimethylbenzoylphosphinate (LAP) and rabbit MSCs (1 × 10 6 ) cells/ml into the NP. Samples were then photopolymerized in situ using non‐ultraviolet light irradiation via a fiberoptic wire. For the in vitro arm of this study, gene expression analysis demonstrated increased anabolic activity in irradiated MSCs with and without biogel scaffolds. For the in vivo arm of this study, while GAG analysis did not demonstrate significant differences between groups, MRI analysis exhibited a trend toward improved NP matrix. Histological analysis was consistent with increased cellularity and less severe disc degeneration in the MSC + Gel group. However, osteophyte formation was noted in both Stab and MSC + Gel groups after the study period. Increased matrix gene expression of irradiated groups within in vitro studies indicates a photobiologic effect of 405 nm light. Despite promising anabolic actions, osteophyte formation and AF defects could not be avoided with implementation of this minimally‐invasive tissue‐engineering approach. © 2018 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 37:1451–1459, 2019.
    Type of Medium: Online Resource
    ISSN: 0736-0266 , 1554-527X
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 2050452-4
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  • 10
    In: Acta Odontologica Scandinavica, Informa UK Limited, Vol. 39, No. 6 ( 1981-01), p. 333-347
    Type of Medium: Online Resource
    ISSN: 0001-6357 , 1502-3850
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 1981
    detail.hit.zdb_id: 1484330-4
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