In:
International Journal of Cancer, Wiley, Vol. 138, No. 8 ( 2016-04-15), p. 1994-2002
Abstract:
What's new? Folate receptor alpha can be found on malignant ovarian cancer cells, but not normal cells. Better yet, it sheds into the bloodstream, making it a tempting candidate for diagnostic testing. These authors sampled the blood of patients suspected of having ovarian cancer, looking for FRA. They found that people with ovarian cancer had high levels of FRA in the bloodstream, while those with other gynecological disease, or metastatic ovarian tumors from colorectal cancer, did not. The amount of FRA strongly correlated with tumor grade, histological type, and clinical stage, making it potentially very effective as a diagnostic tool.
Type of Medium:
Online Resource
ISSN:
0020-7136
,
1097-0215
Language:
English
Publisher:
Wiley
Publication Date:
2016
detail.hit.zdb_id:
218257-9
detail.hit.zdb_id:
1474822-8
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