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  • 1
    In: Water, MDPI AG, Vol. 15, No. 15 ( 2023-07-30), p. 2767-
    Abstract: Global extreme weather events such as rainstorms, floods and droughts have become increasingly frequent, posing significant threats to human beings worldwide. Green infrastructure has been implemented for decades to mitigate these issues. However, its widespread adoption in cities is still limited. A lack of sustainable funds was viewed as a great challenge for its widespread implementation. Many developed countries have practiced public participation and stormwater fee systems to mitigate these challenges. To assess the value that citizens place on the ecosystem benefits provided by urban green infrastructure is of great importance for increasing public participation and their willingness to pay. Thus, this paper aims to explore public preferences and their willingness to pay for the benefits of green infrastructure to support the construction and maintenance costs. A discrete choice experiment method was employed and five attributes were selected: reduction in run-off pollutant, degrees of ponding, plant type, planting aesthetics and the amount of payment. The Ngene1.2 software was used to generate a questionnaire, and data collected from the case cities, Xianyang and Xi’xian New Area, China, were analyzed using the mixed logit model. The results revealed that in Xianyang, the willingness to pay was not significantly associated with cognition, while in Xi’xian New Area, willingness to pay was positively related to cognition. Respondents exhibited a significant willingness to pay for green infrastructure to achieve reduced degrees of ponding in both cities, as well as improving planting aesthetics in Xi’xian New Area. Based on these findings, we conclude that government decision-makers should prioritize disseminating knowledge about green infrastructure to residents before implementing such projects in communities. The findings provide valuable insights into the potential economic value of urban green infrastructure and can guide policymakers and urban planners in making decisions regarding the design, implementation, and management of green infrastructure. This study contributes to the understanding of citizen perspectives and the economic evaluation of ecosystem services provided by urban green infrastructure.
    Type of Medium: Online Resource
    ISSN: 2073-4441
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2521238-2
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  • 2
    Online Resource
    Online Resource
    Oxford University Press (OUP) ; 2022
    In:  Nucleic Acids Research Vol. 50, No. 21 ( 2022-11-28), p. e126-e126
    In: Nucleic Acids Research, Oxford University Press (OUP), Vol. 50, No. 21 ( 2022-11-28), p. e126-e126
    Abstract: Single-cell ATAC-seq (scATAC-seq) has proven to be a state-of-art approach to investigating gene regulation at the single-cell level. However, existing methods cannot precisely uncover cell-type-specific binding of transcription regulators (TRs) and construct gene regulation networks (GRNs) in single-cell. ChIP-seq has been widely used to profile TR binding sites in the past decades. Here, we developed SCRIP, an integrative method to infer single-cell TR activity and targets based on the integration of scATAC-seq and a large-scale TR ChIP-seq reference. Our method showed improved performance in evaluating TR binding activity compared to the existing motif-based methods and reached a higher consistency with matched TR expressions. Besides, our method enables identifying TR target genes as well as building GRNs at the single-cell resolution based on a regulatory potential model. We demonstrate SCRIP’s utility in accurate cell-type clustering, lineage tracing, and inferring cell-type-specific GRNs in multiple biological systems. SCRIP is freely available at https://github.com/wanglabtongji/SCRIP.
    Type of Medium: Online Resource
    ISSN: 0305-1048 , 1362-4962
    RVK:
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2022
    detail.hit.zdb_id: 1472175-2
    SSG: 12
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  • 3
    In: Advanced Functional Materials, Wiley, Vol. 31, No. 15 ( 2021-04)
    Abstract: The spin injection into 2D electron gas (2DEG) in AlN/GaN heterostructures is studied by magneto‐transport measurements. An ultrathin AlN layer at the hetero‐interface acts as a barrier to form high‐quality 2DEG in the triangular quantum well and a tunneling barrier for the spin injection to overcome the conductance mismatch issue. In this study, Hanle signals and inversed Hanle signals are observed, proving that the spin injection is achieved in the 2DEG in the AlN/GaN heterostructure rather than in the interfacial states. The spin‐relaxation time in 2DEG at 8 K is found to be as long as 860 ps, which almost keeps constant with bias and decreases with increasing temperature. The spin‐relaxation process is illustrated as Rashba spin‐orbit coupling dominated D'yakonov Perel’ mechanisms above 8 K. These results show the promising potential of 2DEG in AlN/GaN heterostructures for spin field‐effect transistor applications.
    Type of Medium: Online Resource
    ISSN: 1616-301X , 1616-3028
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 2029061-5
    detail.hit.zdb_id: 2039420-2
    SSG: 11
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  • 4
    Online Resource
    Online Resource
    MDPI AG ; 2022
    In:  International Journal of Molecular Sciences Vol. 23, No. 18 ( 2022-09-09), p. 10428-
    In: International Journal of Molecular Sciences, MDPI AG, Vol. 23, No. 18 ( 2022-09-09), p. 10428-
    Abstract: Oral squamous cell carcinoma (OSCC) is one of the top 15 most prevalent cancers worldwide. However, the current treatment models for OSCC (e.g., surgery, chemotherapy, radiotherapy, and combination therapy) present several limitations: damage to adjacent healthy tissue, possible recurrence, low efficiency, and severe side effects. In this context, nanomaterial-based photothermal therapy (PTT) has attracted extensive research attention. This paper reviews the latest progress in the application of biological nanomaterials for PTT in OSCC. We divide photothermal nanomaterials into four categories (noble metal nanomaterials, carbon-based nanomaterials, metal compounds, and organic nanomaterials) and introduce each category in detail. We also mention in detail the drug delivery systems for PTT of OSCC and briefly summarize the applications of hydrogels, liposomes, and micelles. Finally, we note the challenges faced by the clinical application of PTT nanomaterials and the possibility of further improvement, providing direction for the future research of PTT in OSCC treatment.
    Type of Medium: Online Resource
    ISSN: 1422-0067
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2019364-6
    SSG: 12
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  • 5
    In: DIGITAL HEALTH, SAGE Publications, Vol. 9 ( 2023-01), p. 205520762311659-
    Abstract: In solving the global challenge of sleep disorders, Mobile Health app is one of the important means to monitor, diagnose, and intervene in sleep disorders. This study aims to (1) summarize the status and trends of research in this field; (2) assess the production and usage of sleep mHealth apps; (3) calculate the conversion rate of grants that the proportion of newly developed apps from being funded and developed to published on application stores. Methods Using bibliometric and content analysis methods, based on “Research Paper-Product Output-Product Application” chain and considering the “Research Grants” of articles, we conducted a systematic review of eight databases, to identify relevant studies over the last decade. Results Over the past decade, 1399 authors published 313 papers in 182 journals and conferences. The number of publications increased with an average annual growth of 41.6%. The current focus area is research using cognitive behavioral therapy to intervene in sleep. Sleep-staging tracking is a shortcoming of this field. A total 368 sleep mHealth apps (233 newly developed and 135 existing) were examined in 313 papers; 323 grants supported 178 articles (56.9%). Only 12 of the newly developed apps are used in the real world, resulting in a 9% grant conversion rate. Conclusions In the last decade, the field of tracking, diagnosing, and intervening in sleep disorders using mHealth apps has shown a trend of rapid development. However, the conversion rate of products from being funded and developed for use by end-users is low.
    Type of Medium: Online Resource
    ISSN: 2055-2076 , 2055-2076
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2819396-9
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  • 6
    Online Resource
    Online Resource
    Elsevier BV ; 2023
    In:  Heliyon Vol. 9, No. 1 ( 2023-01), p. e13152-
    In: Heliyon, Elsevier BV, Vol. 9, No. 1 ( 2023-01), p. e13152-
    Type of Medium: Online Resource
    ISSN: 2405-8440
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2023
    detail.hit.zdb_id: 2835763-2
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  • 7
    Online Resource
    Online Resource
    SAGE Publications ; 2022
    In:  Proceedings of the Institution of Mechanical Engineers, Part J: Journal of Engineering Tribology Vol. 236, No. 3 ( 2022-03), p. 514-526
    In: Proceedings of the Institution of Mechanical Engineers, Part J: Journal of Engineering Tribology, SAGE Publications, Vol. 236, No. 3 ( 2022-03), p. 514-526
    Abstract: In this study, the wear failure behaviour of coated self-lubricating spherical plain bearings under different working conditions in the light-load and low-frequency range was studied using a swing wear life tester. The commercial GE17ES bearing was the main research object, and the wear state of the bearing was monitored in real time using torque and temperature rise signals. Furthermore, a scanning electron microscope and an energy dispersive X-ray spectroscope were adopted to analyse the wear failure mechanism of bearings. The results indicated that the friction torque and temperature rise signal changes were mainly divided into three stages, and the characteristics of similar changes could be maintained under different working conditions. Furthermore, at the end of the bearing life, the torque and temperature rise had abrupt changes almost at the same time, which indicated the occurrence of bearing failure. In general, the wear failure mechanisms of bearings included abrasive wear and adhesive wear. Moreover, fatigue wear and oxidation wear were under some conditions. The torque and temperature rise comprehensively reflected the service state of coated self-lubricating spherical plain bearings, which could be used as a physical criterion for determining bearing failure. These results had a strong prospect of engineering application, and were expected to provide a reference for determining the failure behaviour of multi-type coated self-lubricating spherical plain bearings in the future, and provided theoretical support for establishing relevant test standards.
    Type of Medium: Online Resource
    ISSN: 1350-6501 , 2041-305X
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2032767-5
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  • 8
    Online Resource
    Online Resource
    Institution of Engineering and Technology (IET) ; 2018
    In:  IET Computer Vision Vol. 12, No. 8 ( 2018-12), p. 1179-1187
    In: IET Computer Vision, Institution of Engineering and Technology (IET), Vol. 12, No. 8 ( 2018-12), p. 1179-1187
    Abstract: In this study, a novel multi‐layer fused convolution neural network (MLF‐CNN) is proposed for detecting pedestrians under adverse illumination conditions. Currently, most existing pedestrian detectors are very likely to be stuck under adverse illumination circumstances such as shadows, overexposure, or nighttime. To detect pedestrians under such conditions, the authors apply deep learning for effective fusion of the visible and thermal information in multispectral images. The MLF‐CNN consists of a proposal generation stage and a detection stage. In the first stage, they design an MLF region proposal network and propose to use summation fusion method for integration of the two convolutional layers. This combination can detect pedestrians in different scales, even in adverse illumination. Furthermore, instead of extracting features from a single layer, they extract features from three feature maps and match the scale using the fused ROI pooling layers. This new multiple‐layer fusion technique can significantly reduce the detection miss rate. Extensive evaluations of several challenging datasets well demonstrate that their approach achieves state‐of‐the‐art performance. For example, their method performs 28.62% better than the baseline method and 11.35% better than the well‐known faster R‐CNN halfway fusion method in detection accuracy on KAIST multispectral pedestrian dataset.
    Type of Medium: Online Resource
    ISSN: 1751-9632 , 1751-9640
    URL: Issue
    Language: English
    Publisher: Institution of Engineering and Technology (IET)
    Publication Date: 2018
    detail.hit.zdb_id: 2278768-9
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  • 9
    In: Journal of Dental Sciences, Elsevier BV, ( 2023-6)
    Type of Medium: Online Resource
    ISSN: 1991-7902
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2023
    detail.hit.zdb_id: 2502332-9
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  • 10
    Online Resource
    Online Resource
    MDPI AG ; 2022
    In:  Pharmaceutics Vol. 14, No. 10 ( 2022-10-21), p. 2250-
    In: Pharmaceutics, MDPI AG, Vol. 14, No. 10 ( 2022-10-21), p. 2250-
    Abstract: Periodontitis is a dysbiotic biofilm-induced and host-mediated inflammatory disease of tooth supporting tissues that leads to progressive destruction of periodontal ligament and alveolar bone, thereby resulting in gingival recession, deep periodontal pockets, tooth mobility and exfoliation, and aesthetically and functionally compromised dentition. Due to the improved biopharmaceutical and pharmacokinetic properties and targeted and controlled drug release, nano-based drug delivery systems have emerged as a promising strategy for the treatment of periodontal defects, allowing for increased efficacy and safety in controlling local inflammation, establishing a regenerative microenvironment, and regaining bone and attachments. This review provides an overview of nano-based drug delivery systems and illustrates their practical applications, future prospects, and limitations in the field of periodontal tissue regeneration.
    Type of Medium: Online Resource
    ISSN: 1999-4923
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2527217-2
    SSG: 15,3
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