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  • 1
    Online Resource
    Online Resource
    The accuracy of whole-body 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) in the detection of ovarian cancer relapse in patients with rising cancer antigen 125 (CA-125) levels
    Springer Science and Business Media LLC ; 2023
    In:  Egyptian Journal of Radiology and Nuclear Medicine Vol. 54, No. 1 ( 2023-09-20)
    Details
    In: Egyptian Journal of Radiology and Nuclear Medicine, Springer Science and Business Media LLC, Vol. 54, No. 1 ( 2023-09-20)
    Abstract: 18 F-fluorodeoxyglucose (FDG) PET/CT is a noninvasive imaging tool that has been used successfully for the diagnosis, staging, restaging, therapy monitoring, and prognostic prediction of ovarian cancer. For ovarian cancer surveillance, rising CA-125 levels raise the suspicion of recurrence despite its reported low specificity; being elevated in other benign and inflammatory conditions, and thus, confirmation is required. This work aimed to evaluate the role of 18 F-FDG PET/CT in suspected ovarian cancer recurrence in patients presenting with elevated CA-125 levels. Results Fifty female patients with suspected ovarian cancer recurrence owing to elevated CA-125 levels were included in this study. Recurrence was confirmed in 46/50 cases whether by histopathological confirmation or by serial follow-up imaging and clinical follow-up. Positive PET/CT findings were reported in 45/50 cases with 2 false-negative cases and 1 false-positive case. PET/CT examination was found to be superior to contrast-enhanced CT in the detection of peritoneal metastatic nodules and metastatic lymph nodes. According to this study, the estimated sensitivity, specificity, and overall diagnostic accuracy of PET/CT in the detection of recurrent ovarian cancer were 95.6%, 75%, and 94%, respectively. Conclusions In ovarian cancer surveillance, 18 F-FDG PET/CT was found to be a sensitive and accurate noninvasive imaging tool that can be used in the detection of recurrent ovarian cancer in patients with elevated CA-125 levels, thus interfering with the management plan. The advantage of whole-body imaging in PET/CT allows for the detection and precise localization of recurrent or metastatic foci in abdominal and extra-abdominal sites as well.
    Type of Medium: Online Resource
    ISSN: 2090-4762
    URL: Article
    DOI: 10.1186/s43055-023-01108-8
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 2583928-7
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  • 2
    Online Resource
    Online Resource
    An integrated imaging approach for diagnosis of cervico-vaginal outflow defects and associated genital anomalies
    Springer Science and Business Media LLC ; 2015
    In:  The Egyptian Journal of Radiology and Nuclear Medicine Vol. 46, No. 4 ( 2015-12), p. 1249-1256
    Details
    In: The Egyptian Journal of Radiology and Nuclear Medicine, Springer Science and Business Media LLC, Vol. 46, No. 4 ( 2015-12), p. 1249-1256
    Type of Medium: Online Resource
    ISSN: 0378-603X
    URL: Article
    DOI: 10.1016/j.ejrnm.2015.06.014
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2015
    detail.hit.zdb_id: 2583928-7
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  • 3
    Online Resource
    Online Resource
    Role of MRI versus ultrasound in the assessment of placental abnormalities and diseases
    Springer Science and Business Media LLC ; 2016
    In:  The Egyptian Journal of Radiology and Nuclear Medicine Vol. 47, No. 2 ( 2016-06), p. 641-658
    Details
    In: The Egyptian Journal of Radiology and Nuclear Medicine, Springer Science and Business Media LLC, Vol. 47, No. 2 ( 2016-06), p. 641-658
    Type of Medium: Online Resource
    ISSN: 0378-603X
    URL: Article
    DOI: 10.1016/j.ejrnm.2016.02.006
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2016
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  • 4
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    Online Resource
    Role of diffusion weighted imaging and dynamic contrast enhanced MR mammography to detect recurrence in breast cancer patients after surgery
    Springer Science and Business Media LLC ; 2016
    In:  The Egyptian Journal of Radiology and Nuclear Medicine Vol. 47, No. 3 ( 2016-09), p. 1151-1157
    Details
    In: The Egyptian Journal of Radiology and Nuclear Medicine, Springer Science and Business Media LLC, Vol. 47, No. 3 ( 2016-09), p. 1151-1157
    Type of Medium: Online Resource
    ISSN: 0378-603X
    URL: Article
    DOI: 10.1016/j.ejrnm.2016.04.008
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2016
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  • 5
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    Online Resource
    Additive value of fetal MRI to different ultrasound modalities in diagnosis of fetal GIT and abdominal wall anomalies
    Springer Science and Business Media LLC ; 2023
    In:  Egyptian Journal of Radiology and Nuclear Medicine Vol. 54, No. 1 ( 2023-03-24)
    Details
    In: Egyptian Journal of Radiology and Nuclear Medicine, Springer Science and Business Media LLC, Vol. 54, No. 1 ( 2023-03-24)
    Abstract: Fetal MRI is a valuable supplementary study to the prenatal US in accurate diagnosis of fetal gastrointestinal anomalies and ventral abdominal wall anomalies, which has an impact on the postnatal outcome. Aim of work To establish the additive role of fetal MRI to the prenatal US in the identification of complex fetal GIT anomalies. Methods This prospective study involved 36 pregnant patients with age range from 19 to 41 years (mean ± SD of 27.8 ± 5.3 years). Thirty-six fetuses (19 males and 17 females). All cases underwent dedicated 2D obstetric ultrasound assessment with a focus on the fetal abdomen and some cases required additional 3D and 4D assessment. Twenty-seven patients underwent fetal MRI procedures. Results In our study, fetal MRI was significantly more accurate than US in the confirmation and accurate delineation of the level of small bowel obstruction and differentiation of complete obstruction from luminal stenosis. In cases of anorectal malformations, prenatal US and fetal MRI were equally sensitive in the detection of their associated findings. While fetal MRI was superior to the US in the case of congenital chloride diarrhea. MRI images added the presence of distended oropharynx in esophageal atresia cases while other findings were detected with the same accuracy with both US and MRI. In cases of ventral abdominal wall defects, fetal MRI added fine details about the true size of the defect, the actual content of the abdominal wall defect as well as the detection of the presence of large bowel loops and related complications. In the category of fetal abdominal cysts, fetal MRI was superior to the US owing to its greater soft tissue characterization. In the case of sacrococcygeal teratoma (SCT), fetal MRI detected an additional intra-pelvic extension upgrading the tumor and detecting the true size of the intra-spinal component. In the category of congenital diaphragmatic hernia, MRI was superior in the detection of hernia capsule, herniated liver, and associated complications as well as accurate estimation of fetal lung volume. Studying the cases of cloacal malformations showed that owing to better tissue characterization by MRI the anomaly and its associated abnormal genitourinary communication were better delineated by MRI. The sensitivity of MRI to detect congenital anomalies concerning postnatal findings was 100%, the specificity was 50% and diagnostic accuracy was 96.6%. The sensitivity of ultrasound to detect congenital anomalies concerning postnatal findings was 85.3%, the specificity was 89%, and diagnostic accuracy was 80.6%. The sensitivity of combined US and MRI to detect congenital anomalies concerning postnatal findings was 100%, the specificity was 89%, and diagnostic accuracy was 93.1%. Conclusions Fetal MRI is a valuable supplementary study to the prenatal US in accurate diagnosis of fetal obstructive gastrointestinal anomalies, ventral abdominal wall anomalies, fetal abdominal cysts, masses, and congenital diaphragmatic hernia . Fetal MRI is equally sensitive to the prenatal US in anorectal malformations.
    Type of Medium: Online Resource
    ISSN: 2090-4762
    URL: Article
    DOI: 10.1186/s43055-023-00997-z
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
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  • 6
    Online Resource
    Online Resource
    Swyer syndrome with malignant germ cell tumor: a case report
    Springer Science and Business Media LLC ; 2021
    In:  Egyptian Journal of Radiology and Nuclear Medicine Vol. 52, No. 1 ( 2021-12)
    Details
    In: Egyptian Journal of Radiology and Nuclear Medicine, Springer Science and Business Media LLC, Vol. 52, No. 1 ( 2021-12)
    Abstract: Swyer syndrome (Pure gonadal dysgenesis, 46 XY) is a rare form of disorder of sexual development. These patients presented with external female phenotype, normal Mullerian structures and streak gonads. Pure gonadal dysgenesis, XY patients are more likely to develop germ cell tumors due to the presence of the Y chromosome. Case presentation A 19-year-old patient with a female external phenotype presented with primary amenorrhea. Clinical examination, Karyotyping, imaging, and histopathological assessment revealed Swyer syndrome. On imaging, a right adnexal mass with calcification was detected. Laparoscopic surgery with histopathology revealed a malignant germ cell tumor. Conclusions Swyer syndrome represents a rare form of sexual development that necessitates a meticulous clinical, laboratory and radiological evaluation. Clinically, the patients have a female external phenotype with 46xy Karyotyping. Imaging, Ultrasound is the primary imaging modality Imaging and MRI helps in detection of the exact site of streak gonads and characterization of lesions. CT is useful in detecting calcification, which is a hallmark in the diagnosis of gonadoblastoma. Early diagnosis of Swyer syndrome is crucial as prophylactic gonadectomy in these cases reduces the risk of developing germ cell tumors.
    Type of Medium: Online Resource
    ISSN: 2090-4762
    URL: Article
    DOI: 10.1186/s43055-021-00599-7
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
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  • 7
    Online Resource
    Online Resource
    Surface transperineal ultrasound and vaginal abnormalities: applications and strengths
    British Institute of Radiology ; 2017
    In:  The British Journal of Radiology ( 2017-11), p. 20170326-
    Details
    In: The British Journal of Radiology, British Institute of Radiology, ( 2017-11), p. 20170326-
    Type of Medium: Online Resource
    ISSN: 0007-1285 , 1748-880X
    URL: Article
    DOI: 10.1259/bjr.20170326
    RVK:
    XA 34700
    Language: English
    Publisher: British Institute of Radiology
    Publication Date: 2017
    detail.hit.zdb_id: 1468548-6
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  • 8
    Online Resource
    Online Resource
    Classification of Inflammatory Breast Disorders and Step by Step Diagnosis
    Hindawi Limited ; 2009
    In:  The Breast Journal Vol. 15, No. 4 ( 2009-07), p. 367-380
    Details
    In: The Breast Journal, Hindawi Limited, Vol. 15, No. 4 ( 2009-07), p. 367-380
    Type of Medium: Online Resource
    ISSN: 1075-122X , 1524-4741
    URL: Issue
    URL: Article
    DOI: 10.1111/tbj.2009.15.issue-4
    DOI: 10.1111/j.1524-4741.2009.00740.x
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2009
    detail.hit.zdb_id: 2020959-9
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  • 9
    Online Resource
    Online Resource
    Fetal Cerebellar Vermis Assessment by MRI. What Does It Add?
    Scientific Research Publishing, Inc. ; 2019
    In:  Open Journal of Obstetrics and Gynecology Vol. 09, No. 09 ( 2019), p. 1290-1303
    Details
    In: Open Journal of Obstetrics and Gynecology, Scientific Research Publishing, Inc., Vol. 09, No. 09 ( 2019), p. 1290-1303
    Type of Medium: Online Resource
    ISSN: 2160-8792 , 2160-8806
    URL: Article
    DOI: 10.4236/ojog.2019.99125
    Language: Unknown
    Publisher: Scientific Research Publishing, Inc.
    Publication Date: 2019
    detail.hit.zdb_id: 2619426-0
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  • 10
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    Online Resource
    Axillary lymph node status in BIRADS 4-5 female patients: can shear wave and strain ultrasound elastography help?
    Springer Science and Business Media LLC ; 2021
    In:  Egyptian Journal of Radiology and Nuclear Medicine Vol. 52, No. 1 ( 2021-12)
    Details
    In: Egyptian Journal of Radiology and Nuclear Medicine, Springer Science and Business Media LLC, Vol. 52, No. 1 ( 2021-12)
    Abstract: The status of axillary nodes is a determining factor of management and prognosis for patients having a recent diagnosis of breast cancer. Axillary nodes are usually evaluated by ultrasonography (US) and biopsy, if indicated. Ultrasound-guided sampling and intraoperative or sentinel nodal sampling are available options, however, are invasive and hold risks of potential complications, calling for reliable, non-invasive axillary imaging. In the current prospective study, we assessed the performance of shear wave (SWE) and strain (SE) ultrasound elastography regarding preoperative axillary assessment. Sixty axillary nodes from 60 patients (age 28–65 years, mean 49.88 ± 7.61 SD) were included, all scoring BIRADS 4–5 on sonomammography. Results For US, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy were 100%, 66.67%, 84.78%, 100%, and 88.33%, respectively. Cortical thickness and vascularity were the most sensitive. For qualitative SWE, indices were 76.92%, 80.95%, 88.24%, 65.38% and 78.33%, respectively. Calculated cut-off for Emax was 59.3 and for Eratio was 4.56, giving statistical indices of 76.9%, 90.5%, 93.75%, 67.86%, and 81.67% for Emax and 76.9%, 100%, 100%, 70% and 85% respectively for Eratio. Both Emax and Eratio were greater for malignant (Emax 81.77 ± 1.904, Eratio 8.95 ± 5.69) than for benign nodes (Emax 37.59 ± 33.37, Eratio 2.5 ± 1.37) ( P values 〈 0.001). For qualitative SE, sensitivity and specificity were 92.31% and 57.14%, while PPV, NPV, and accuracy were 80% each ( P values 〈 0.001). The calculated cut-off value for SR was 3.85, giving indices of 87.2%, 76.2%, 76.19%, 87.18% and 83.33% respectively. Conclusion Adding elastography evaluation to conventional US positively impacts the specificity and accuracy of the preoperative axillary nodal status assessment in patients having newly diagnosed breast cancer.
    Type of Medium: Online Resource
    ISSN: 2090-4762
    URL: Article
    DOI: 10.1186/s43055-021-00560-8
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
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