In:
European Journal of Organic Chemistry, Wiley, Vol. 2017, No. 13 ( 2017-04-03), p. 1704-1712
Abstract:
A simple method for the preparation of arylnaphthalene lactone natural products was developed and used to synthesize diphyllin ( 10 ), justicidin A ( 12 ), cilinaphthalide B ( 13 ), taiwanin E ( 15 ), chinensinaphthol ( 16 ), taiwanin E methyl ether ( 17 ), chinensinaphthol methyl ether ( 18 ), justicidin C ( 21 ), and justicidin D ( 22 ). Key steps of the syntheses include the Hauser–Kraus annulation of cyanophthalides 7a and 7b and Suzuki–Miyaura cross‐coupling reactions between arylnaphthalene lactones that contain a sulfonate group (i.e., 9 , 14 , 19 , and 20 ) and various potassium aryltrifluoroborates.
Type of Medium:
Online Resource
ISSN:
1434-193X
,
1099-0690
DOI:
10.1002/ejoc.v2017.13
DOI:
10.1002/ejoc.201601611
Language:
English
Publisher:
Wiley
Publication Date:
2017
detail.hit.zdb_id:
1475010-7
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