In:
Annual Review of Pathology: Mechanisms of Disease, Annual Reviews, Vol. 14, No. 1 ( 2019-01-24), p. 211-238
Abstract:
Cardiovascular diseases exist across all developed countries. Biomarkers that can predict or diagnose diseases early in their pathogeneses can reduce their morbidity and mortality in afflicted individuals. microRNAs are small regulatory RNAs that modulate translation and have been identified as potential fluid-based biomarkers across numerous maladies. We describe the current state of cardiovascular disease biomarkers across a range of diseases, including myocardial infarction, acute coronary syndrome, myocarditis, hypertension, heart failure, heart transplantation, aortic stenosis, diabetic cardiomyopathy, atrial fibrillation, and sepsis. We present the current understanding of microRNAs as possible biomarkers in these categories and where their best opportunities exist to enter clinical practice.
Type of Medium:
Online Resource
ISSN:
1553-4006
,
1553-4014
DOI:
10.1146/pathmechdis.2019.14.issue-1
DOI:
10.1146/annurev-pathmechdis-012418-012827
Language:
English
Publisher:
Annual Reviews
Publication Date:
2019
detail.hit.zdb_id:
2217576-3
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