In:
The Journal of Clinical Hypertension, Wiley, Vol. 17, No. 5 ( 2015-05), p. 340-348
Abstract:
To study whether sleep blood pressure ( BP ) self‐measured at home is associated with organ damage, the authors analyzed the data of 2562 participants in the J‐ HOP study who self‐measured sleep BP using a home BP monitoring ( HBPM ) device, three times during sleep (2 am , 3 am , 4 am ), as well as the home morning and evening BP s. The mean sleep home systolic BP s (SBPs) were all correlated with urinary albumin/creatinine ratio ( UACR ), left ventricular mass index ( LVMI ), brachial‐ankle pulse wave velocity (ba PWV ), maximum carotid intima‐media thickness, and plasma N‐terminal pro‐hormone pro–brain‐type natriuretic peptide (NTproBNP) (all P 〈 .001). After controlling for clinic SBP and home morning and evening SBP s, associations of home sleep SBP with UACR , LVMI , and ba PWV remained significant (all P 〈 .008). Even in patients with home morning BP 〈 135/85 mm Hg, 27% exhibited masked nocturnal hypertension with home sleep SBP ≥120 mm Hg and had higher UACR and NT pro BNP . Masked nocturnal hypertension, which is associated with advanced organ damage, remains unrecognized by conventional HBPM .
Type of Medium:
Online Resource
ISSN:
1524-6175
,
1751-7176
DOI:
10.1111/jch.2015.17.issue-5
Language:
English
Publisher:
Wiley
Publication Date:
2015
detail.hit.zdb_id:
2058690-5
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