In:
Organic Chemistry Frontiers, Royal Society of Chemistry (RSC), Vol. 8, No. 22 ( 2021), p. 6427-6432
Abstract:
A palladium catalyzed desulfurative coupling of allylthioethers with organoboronic acids under mild reaction conditions is described. The reaction exhibits high chemoselectivity and good functional group tolerance, allowing the synthesis of a wide range of α-branched enones. In addition, this approach enables a new retrosynthetic disconnection to multi-functionalised allylic molecules via selective cleavage of the C–S bond, thus providing a complementary allylation protocol to Tsuji–Trost reactions.
Type of Medium:
Online Resource
ISSN:
2052-4129
Language:
English
Publisher:
Royal Society of Chemistry (RSC)
Publication Date:
2021
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