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  • 1
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    Online Resource
    Intracranial meningioma causing partial amaurosis in a cat
    Wiley ; 2011
    In:  Veterinary Ophthalmology Vol. 14, No. s1 ( 2011-09), p. 93-98
    Details
    In: Veterinary Ophthalmology, Wiley, Vol. 14, No. s1 ( 2011-09), p. 93-98
    Abstract: Objective  To describe a case of intracranial meningioma causing visual impairment in a cat, successfully treated by surgery. Procedures  An adult neutered male domestic cat was referred with a 10‐month history of progressive visual impairment and altered behavior. Investigations included physical, ophthalmologic and neurological examinations as well as hematology, serum biochemistry and CT scan of the head. Results  The menace response was absent in the left eye and decreased in the right eye. Electroretinograms were normal on both eyes, as was ophthalmic examination, ruling out an ocular cause and allowing a presumptive diagnosis of partial amaurosis due to a post‐retinal lesion. CT scan demonstrated a large sessile extra axial mass along the right parietal bone and thickening of the adjacent bone. Cerebrospinal fluid was not collected because high intracranial pressure represented a risk for brain herniation. A right rostrotentorial craniectomy was performed to remove the tumor. Ten days after surgery, vision was improved, neurological examination was normal and normal behavior was restored. Ten months after surgery, ophthalmological examination showed no visual deficit and CT scan did not reveal any sign of recurrence. Conclusion  Advanced imaging techniques allow veterinarians to detect early cerebral diseases and to provide specific treatment when it is possible. In cases of feline amaurosis due to intracranial meningioma, the vital prognosis is good while the visual prognosis is more uncertain, but recovery of normal vision and normal behavior is possible as demonstrated in the present case.
    Type of Medium: Online Resource
    ISSN: 1463-5216 , 1463-5224
    URL: Issue
    URL: Article
    DOI: 10.1111/vop.2011.14.issue-s1
    DOI: 10.1111/j.1463-5224.2011.00904.x
    Language: English
    Publisher: Wiley
    Publication Date: 2011
    detail.hit.zdb_id: 2011043-1
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  • 2
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    Utilisation du laser infrarouge en ophtalmologie vétérinaire
    PERSEE Program ; 2011
    In:  Bulletin de l'Académie Vétérinaire de France Vol. 164, No. 3 ( 2011), p. 217-224
    Details
    In: Bulletin de l'Académie Vétérinaire de France, PERSEE Program, Vol. 164, No. 3 ( 2011), p. 217-224
    Abstract: Use of infra-red laser in veterinary ophthalmology. The infrared diode laser is the most commonly used laser in veterinary ophthalmology. Diode laser has a thermal photocoagulation effect. Laser energy may be delivered through different devices, including transscleral probes, intraocular probes, an operating microscope adapter and an indirect ophthalmoscope headset. The target tissue may be the ciliary body (glaucoma surgery), retina (retinopexy) or any melanin-containing tissue. Infrared laser cyclophotocoagulation produces coagulation necrosis of the ciliary epithelium, the ciliary stroma and its vasculature, thereby decreasing the production of aqueous humour and hence lowering the intraocular pressure. Retinopexy using infrared laser is performed either for prophylaxis or for retinal reattachment surgery. Photocoagulation produces coagulation necrosis resulting in chorioretinal adhesion which maintains the retina attached to the fundus. Finally, the infrared diode laser is also used in veterinary patients for the treatment of pigmented uveal cysts, epibulbar melanoma, and certain benign iris tumours.
    Type of Medium: Online Resource
    ISSN: 0001-4192
    URL: Article
    DOI: 10.4267/2042/48090
    Language: French
    Publisher: PERSEE Program
    Publication Date: 2011
    detail.hit.zdb_id: 2840771-4
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  • 3
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    Pharmacokinetic study of metopimazine by oral route in children
    Wiley ; 2015
    In:  Pharmacology Research & Perspectives Vol. 3, No. 3 ( 2015-06)
    Details
    In: Pharmacology Research & Perspectives, Wiley, Vol. 3, No. 3 ( 2015-06)
    Abstract: Metopimazine ( MPZ ) is an antiemetic considered as a currently used drug. In France, it has become the leading antiemetic mediator due to its good tolerance, however, its pharmacokinetics has never previously been studied in children. MPZ was administered by oral route to 8 children with a single dose of 0.33 mg/kg during an endocrine exploration using stimuli well known for its adverse emetic effects. We used biological remnants from sera following an hGH test in order to obtain the MPZ pharmacokinetics. Plasmatic concentrations of MPZ and the active acid metabolite AMPZ , were quantified by HPLC ‐ MS / MS during a 270 min test period. MPZ is quickly absorbed with a median C max of 17.2 ng/ mL at one hour and its half‐life is 2.18 h. The plasmatic concentrations of AMPZ were higher than MPZ with a median C max of 76.3 ng/ mL , a T max to 150 min and its concentration was approximately maintained at 50 ng/ mL from 1 to 4 h. The plasmatic concentrations in children are similar to those observed in adults. No adverse effects, nausea or vomiting occurred during the trial. Therefore, these results confirm the MPZ dosage that should be used in children under 15 kg administered as 0.33 mg/kg up to 3 times a day.
    Type of Medium: Online Resource
    ISSN: 2052-1707 , 2052-1707
    URL: Article
    DOI: 10.1002/prp2.130
    Language: English
    Publisher: Wiley
    Publication Date: 2015
    detail.hit.zdb_id: 2740389-0
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  • 4
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    Effect of mydriasis induced by topical instillations of 0.5% tropicamide on the anterior segment in normotensive dogs using ultrasound biomicroscopy
    Wiley ; 2012
    In:  Veterinary Ophthalmology Vol. 15, No. s1 ( 2012-03), p. 8-13
    Details
    In: Veterinary Ophthalmology, Wiley, Vol. 15, No. s1 ( 2012-03), p. 8-13
    Abstract: Objective  To determine the effect of 0.5% tropicamide and the resultant mydriasis on the anterior segment in normotensive dogs using ultrasound biomicroscopy. Procedure  Twenty‐four dogs without ocular disease underwent ultrasound biomicroscopic examination of both the eyes under general anesthesia. Pharmacologic mydriasis was induced in the right eye of each dog by the topical instillation of 0.5% tropicamide. Ultrasound biomicroscopic examinations were performed and the anatomical parameters of the anterior segment were evaluated including the geometric iridocorneal angle (ICA) – formed by the plane of the iris root and the internal corneoscleral limbus – the width of the opening of the ciliary cleft (CC), the width of the mid‐CC, the length of the CC, and the anterior chamber (AC) depth (distance between the corneal endothelium and the anterior lens capsule). Results  Mydriasis resulting from the topical use of 0.5% tropicamide is associated with an increase in the geometric ICA and a decrease in the opening of the CC, without any effect on the width of the mid‐CC, or on the length of the CC, or on the AC depth. Conclusions  Mydriasis induced by topical 0.5% tropicamide results in modification of the anterior segment which may influence the drainage of aqueous humor.
    Type of Medium: Online Resource
    ISSN: 1463-5216 , 1463-5224
    URL: Issue
    URL: Article
    DOI: 10.1111/vop.2012.15.issue-s1
    DOI: 10.1111/j.1463-5224.2011.00898.x
    Language: English
    Publisher: Wiley
    Publication Date: 2012
    detail.hit.zdb_id: 2011043-1
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  • 5
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    Use of a porcine urinary bladder acellular matrix for corneal reconstruction in dogs and cats
    Wiley ; 2016
    In:  Veterinary Ophthalmology Vol. 19, No. 6 ( 2016-11), p. 454-463
    Details
    In: Veterinary Ophthalmology, Wiley, Vol. 19, No. 6 ( 2016-11), p. 454-463
    Abstract: To describe the use of a porcine urinary bladder acellular matrix for surgical reconstruction of the cornea in cases of canine and feline deep corneal ulcers, and feline corneal sequestra. Materials and methods Twenty‐seven dogs and three cats with deep corneal ulcers and seven cats with corneal sequestra were included in the study with overall 38 eyes. For each patient, the necrotic material (ie corneal sequestrum or collagenolytic tissue) was removed by circular lamellar keratectomy. The collagen graft was then cut and prepared to match the stromal defect and then sutured into the lamellar keratectomy bed using interrupted and continuous patterns of absorbable polyglactin 9–0 sutures. Postoperative medical treatment consisted of topical and systemic administration of antibiotics, combined with topical administration of atropine sulfate. The animals were examined 18, 45, and 90 days after the surgery. Results Postoperative examination revealed complete integration of the biomaterial in 93.5% of ulceration cases in both species and in 100% of feline corneal sequestrum cases. In two cases of ulceration (1 dog and 1 cat), progression of the collagenolytic process at the graft periphery required an additional conjunctival graft 7 days after the first surgery. At 90 days post‐op, 100% of the eyes were sighted. Conclusion Use of a porcine urinary bladder acellular matrix appears to be effective in the surgical management of deep corneal ulcers and feline corneal sequestra.
    Type of Medium: Online Resource
    ISSN: 1463-5216 , 1463-5224
    URL: Issue
    URL: Article
    DOI: 10.1111/vop.2016.19.issue-6
    DOI: 10.1111/vop.12326
    Language: English
    Publisher: Wiley
    Publication Date: 2016
    detail.hit.zdb_id: 2011043-1
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  • 6
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    Ectopic cilia in 112 dogs: A multicenter retrospective study
    Wiley ; 2022
    In:  Veterinary Ophthalmology Vol. 25, No. 2 ( 2022-03), p. 186-190
    Details
    In: Veterinary Ophthalmology, Wiley, Vol. 25, No. 2 ( 2022-03), p. 186-190
    Abstract: The aim of this retrospective study was to review the clinical data and outcomes of patients that suffered ectopic cilium (EC). Animals studied One hundred and twelve dogs from multiple private practices in France, with a clinical diagnosis of EC were included in the study. Results The mean age of affected dogs was 2.3 years. There were 64 females and 48 males. The most represented breeds were the Shi Tzu, the French Bulldog, the English Bulldog and the Chihuahua. Eleven dogs were affected bilaterally. The upper eyelid was implicated in 93.5% of the cases, with the median portion being the most affected. No statistical difference was observed between the right and the left eye. EC were associated with distichiasis in 50% of the cases. Pigmentation of the conjunctiva at the point of exit of the EC was present in 58% of the cases. EC were short in 75% and long in 25% of the cases. Corneal complications were statistically associated with short EC. The corneal lesions associated with EC were keratitis (94%), corneal granuloma (0.8%), corneal fibrosis (2.7%), corneal degeneration (0.8%), superficial corneal ulcer (68.7%), deep corneal ulcer (8%) and perforating corneal ulcer (0.8%). The surgeries which consisted of the removal of the hair follicle was successful in 88.4% of the cases. Conclusion EC is a rare condition which can be treated successfully by the removal of the hair follicles. It must be suspected in cases of corneal lesions unresponsive to medical treatment.
    Type of Medium: Online Resource
    ISSN: 1463-5216 , 1463-5224
    URL: Issue
    URL: Article
    DOI: 10.1111/vop.v25.2
    DOI: 10.1111/vop.12947
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2011043-1
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  • 7
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    Successful bilateral phacoemulsification and vitrectomy in a Bennett’s wallaby (Macropus rufogriseus)
    American Veterinary Medical Association (AVMA) ; 2022
    In:  Journal of the American Veterinary Medical Association Vol. 260, No. 4 ( 2022-02-15), p. 450-454
    Details
    In: Journal of the American Veterinary Medical Association, American Veterinary Medical Association (AVMA), Vol. 260, No. 4 ( 2022-02-15), p. 450-454
    Abstract: A 7-month-old hand-reared female Bennett’s wallaby ( Macropus rufogriseus ) was evaluated for bilateral ocular opacity of 3 months’ duration. CLINICAL FINDINGS On physical examination, the wallaby was in good overall condition. An ophthalmic examination revealed mature cataracts in both eyes (OU). The cataracts were suspected to have a nutritional origin as it has been described in hand-reared macropods. Results of tonometry were normal OU. Results of CBC and serum biochemistry were unremarkable. The wallaby was premedicated with medetomidine and ketamine hydrochloride. Ocular ultrasonography performed while the wallaby was anesthetized revealed a thickened and opaque lens, mildly heterogeneous vitreous humor, and no sign of retinal detachment OU. An electroretinogram confirmed functional retinae OU. TREATMENT AND OUTCOME Surgery was considered necessary for welfare reasons. Phacoemulsification and vitrectomy were performed without intraoperative complication. The wallaby recovered uneventfully, and systemic NSAID, topical corticosteroid, and systemic and topical antimicrobial therapy were prescribed. One year later, the animal had vision OU. Physical examination did not show any vision-threatening postoperative complications. CLINICAL RELEVANCE The etiology of nutritional cataracts is not fully understood in macropods, but this condition is rather common in these species. To our knowledge, this is the first detailed report of a successful bilateral phacoemulsification and vitrectomy in a Bennett’s wallaby.
    Type of Medium: Online Resource
    ISSN: 0003-1488
    URL: Article
    DOI: 10.2460/javma.21.03.0165
    Language: Unknown
    Publisher: American Veterinary Medical Association (AVMA)
    Publication Date: 2022
    detail.hit.zdb_id: 2904887-4
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  • 8
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    Intra‐ and interobserver reliability of lens equatorial length measurement using 35‐ MH z ultrasound biomicroscopy in dogs with cataract
    Wiley ; 2017
    In:  Veterinary Ophthalmology Vol. 20, No. 4 ( 2017-07), p. 329-334
    Details
    In: Veterinary Ophthalmology, Wiley, Vol. 20, No. 4 ( 2017-07), p. 329-334
    Abstract: To determine intra‐ and interobserver reliability of lens equatorial length measurement using 35‐MHz ultrasound biomicroscopy in dogs with cataract. Methods Ocular ultrasonography was performed on 28 dogs (50 eyes) before phacoemulsification. Lens equatorial length was measured on still images obtained at 35 MHz in all dogs. Each observer (A and B) obtained the measurements independently. Coefficients of variation ( CV s) were used to assess intraobserver repeatability and interobserver reproducibility. Intraobserver repeatability was assessed by comparing measurements obtained on the same image on four different occasions by observer A. Interobserver reproducibility was assessed by comparing measurements obtained independently by both observers on the same image. Results CV used to assess intraobserver repeatability was 2.4% with good agreement and no significant difference between repetitions ( P 〉 0.05). CV used to assess interobserver reproducibility was 5.8% without significant difference between measurements obtained by the two observers ( P 〉 0.05). Conclusions Intraobserver repeatability and interobserver reproducibility were considered good for lens equatorial length measurement at 35 MHz in dogs with cataract. Ultrasound biomicroscopy could be an acceptable method to assess lens equatorial dimension before phacoemulsification and intraocular lens implantation in dogs with cataract.
    Type of Medium: Online Resource
    ISSN: 1463-5216 , 1463-5224
    URL: Issue
    URL: Article
    DOI: 10.1111/vop.2017.20.issue-4
    DOI: 10.1111/vop.12423
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 2011043-1
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  • 9
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    Use of bovine pericardium (Tutopatch ® ) graft for surgical repair of deep melting corneal ulcers in dogs and corneal sequestra in cats
    Wiley ; 2014
    In:  Veterinary Ophthalmology Vol. 17, No. 2 ( 2014-03), p. 91-99
    Details
    In: Veterinary Ophthalmology, Wiley, Vol. 17, No. 2 ( 2014-03), p. 91-99
    Abstract: To evaluate the efficacy of bovine pericardium ( BP ) graft in the treatment of deep melting corneal ulcers in three dogs and corneal sequestra in three cats. Procedure Three dogs with keratomalacia affecting the deep third of the stroma and three cats with corneal sequestrum were evaluated and underwent surgery. Following keratectomy, BP material was placed into the keratectomy bed and sutured to the recipient cornea with 9/0 polyglactin suture material. Postoperative treatment with topical and systemic antibiotics, systemic nonsteroidal anti‐inflammatory agents, and topical atropine was prescribed. Follow‐up examinations were carried out 1, 2 weeks, 1 and 2 months after the surgery and consisted of a complete ophthalmic examination. Optical coherence tomography ( OCT ) was performed 1 and 2 months after the surgery in one dog and in one cat. Results At 1 week, corneal neovascularization was present around the BP graft in all cases. Four weeks after the BP graft, in two dogs and in all cats, the vascularization was regressing and the graft was integrated into the cornea, which was regaining transparency. Topical treatment with anti‐inflammatory agents was then prescribed for 2 weeks. Two months after the surgery, 5 of 6 corneas in two dogs and three cats had healed with focal corneal scarring. The remaining dog had progression of the keratomalacia involving the deep BP graft that required additional surgery, but became blind. Conclusion Bovine pericardium graft offers a promising option for surgical reconstruction of the cornea following keratectomy for the management of corneal ulcers and sequestra.
    Type of Medium: Online Resource
    ISSN: 1463-5216 , 1463-5224
    URL: Issue
    URL: Article
    DOI: 10.1111/vop.2014.17.issue-2
    DOI: 10.1111/vop.12047
    Language: English
    Publisher: Wiley
    Publication Date: 2014
    detail.hit.zdb_id: 2011043-1
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  • 10
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    Marsupialization of a cyst of the nictitating membrane in three dogs
    Wiley ; 2017
    In:  Veterinary Ophthalmology Vol. 20, No. 2 ( 2017-03), p. 181-188
    Details
    In: Veterinary Ophthalmology, Wiley, Vol. 20, No. 2 ( 2017-03), p. 181-188
    Abstract: Development of cysts has been reported as a potential complication after surgical repositioning of nictitating membrane gland protrusion using the conjunctival pocket technique. To the authors' knowledge, no treatment for these cysts has ever been published. Objectives This short case series describes a surgical technique of marsupialization as a treatment option for these cysts and proposes a pathogenesis for cyst formation. Cases description Three dogs were each referred for a unilateral subconjunctival mass‐like lesion involving the bulbar side of the nictitating membrane. Complete ophthalmologic examination revealed a pink, translucent, soft, and nonpainful mass protruding from the bulbar surface of the nictitating membrane in all cases. Treatment consisted in marsupialization of the cyst on the palpebral surface of the nictitating membrane and was curative with no short‐term postoperative complication and favorable long‐term outcome for the three dogs. Histopathological findings were consistent with a lacrimal cyst. Conclusion Marsupialization appears to be a safe, simple, and effective treatment for nictitating membrane cyst secondary to surgical correction of gland prolapse using conjunctival pocket technique in dogs. Further studies on a larger number of cases are necessary to determine whether marsupialization is the technique of choice and to further investigate the pathophysiology of cyst formation after conjunctival pocket repositioning of prolapsed glands.
    Type of Medium: Online Resource
    ISSN: 1463-5216 , 1463-5224
    URL: Issue
    URL: Article
    DOI: 10.1111/vop.2017.20.issue-2
    DOI: 10.1111/vop.12382
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 2011043-1
    SSG: 22
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