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  • 1
    Online Resource
    Online Resource
    Synthesis and Cell Imaging of a Near-Infrared Fluorescent Magnetic “CdHgTe–Dextran-Magnetic Layered Double Hydroxide–Fluorouracil” Composite
    Elsevier BV ; 2016
    In:  Journal of Pharmaceutical Sciences Vol. 105, No. 5 ( 2016-05), p. 1751-1761
    Details
    In: Journal of Pharmaceutical Sciences, Elsevier BV, Vol. 105, No. 5 ( 2016-05), p. 1751-1761
    Type of Medium: Online Resource
    ISSN: 0022-3549
    URL: Article
    DOI: 10.1016/j.xphs.2016.02.030
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2016
    detail.hit.zdb_id: 1491821-3
    SSG: 15,3
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  • 2
    Online Resource
    Online Resource
    The adverse skin reactions of health care workers using personal protective equipment for COVID-19
    Ovid Technologies (Wolters Kluwer Health) ; 2020
    In:  Medicine Vol. 99, No. 24 ( 2020-06-12), p. e20603-
    Details
    In: Medicine, Ovid Technologies (Wolters Kluwer Health), Vol. 99, No. 24 ( 2020-06-12), p. e20603-
    Abstract: In December 2019, a new coronavirus was found in Wuhan, Hubei Province, China, and spread rapidly throughout the country, attracting global attention. On February 11, the World Health Organization (WHO) officially named the disease caused by 2019-nCoV coronavirus disease 2019 (COVID-19). With the increasing number of cases, health care workers (HCWs) from all over China volunteered to work in Hubei Province. Because of the strong infectivity of COVID-19, HCWs need to wear personal protective equipment (PPE), such as N95 masks, latex gloves, and protective clothing. Due to the long-term use of PPE, many adverse skin reactions may occur. Therefore, the purpose of this study is to explore the adverse skin reactions among HCWs using PPE. Questionnaires were used for the research; a quantitative study was carried out to determine the incidence of adverse skin reactions among HCWs using PPE. A total of 61 valid questionnaires were collected. The most common adverse skin reactions among HCWs wearing N95 masks were nasal bridge scarring (68.9%) and facial itching (27.9%). The most common adverse skin reactions among HCWs wearing latex gloves were dry skin (55.7%), itching (31.2%), and rash (23.0%). The most common adverse skin reactions among HCWs wearing protective clothing were dry skin (36.1%) and itching (34.4%). When most HCWs wear PPE for a long period of time, they will experience adverse skin reactions. The incidence of adverse skin reactions to the N95 mask was 95.1%, that to latex gloves was 88.5%, and that to protective clothing was 60.7%.
    Type of Medium: Online Resource
    ISSN: 0025-7974 , 1536-5964
    URL: Article
    DOI: 10.1097/MD.0000000000020603
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2020
    detail.hit.zdb_id: 2049818-4
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  • 3
    Online Resource
    Online Resource
    Preparation and characterization of magnetic thermosensitive fluorouracil micelles
    Informa UK Limited ; 2016
    In:  Journal of Biomaterials Science, Polymer Edition Vol. 27, No. 8 ( 2016-05-23), p. 773-791
    Details
    In: Journal of Biomaterials Science, Polymer Edition, Informa UK Limited, Vol. 27, No. 8 ( 2016-05-23), p. 773-791
    Type of Medium: Online Resource
    ISSN: 0920-5063 , 1568-5624
    URL: Article
    DOI: 10.1080/09205063.2016.1162626
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 2016
    detail.hit.zdb_id: 2049006-9
    SSG: 12
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  • 4
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    Linking Challenge–Hindrance Stressors to Safety Outcomes and Performance: A Dual Mediation Model for Construction Workers
    MDPI AG ; 2020
    In:  International Journal of Environmental Research and Public Health Vol. 17, No. 21 ( 2020-10-27), p. 7867-
    Details
    In: International Journal of Environmental Research and Public Health, MDPI AG, Vol. 17, No. 21 ( 2020-10-27), p. 7867-
    Abstract: Occupational stressors have long been recognized as an important risk factor for injury accidents. The mechanisms underlying the relationships among challenge stressors, hindrance stressors, safety outcomes (occupational injuries), emotional experiences (attentiveness), and job performance (task performance) were investigated from the perspectives of the challenge–hindrance stress model and the conservation of resources theory. This study collected multi-source data over two timepoints for 105 safety supervisors and 379 construction workers in China. Results revealed that both challenge and hindrance stressors were positively related to occupational injuries, but only challenge stressors were positively associated with attentiveness. In addition, occupational injuries mediated the relationship between both challenge and hindrance stressors and task performance, while attentiveness mediated only the relationship between challenge stressors and task performance. These findings contribute to our knowledge of stress management in the construction project context and provide recommendations for stress management for front-line workers at construction sites.
    Type of Medium: Online Resource
    ISSN: 1660-4601
    URL: Article
    DOI: 10.3390/ijerph17217867
    Language: English
    Publisher: MDPI AG
    Publication Date: 2020
    detail.hit.zdb_id: 2175195-X
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  • 5
    Online Resource
    Online Resource
    Differences in Mechanisms Linking Motivation and Turnover Intention for Public and Private Employees: Evidence From China
    SAGE Publications ; 2021
    In:  SAGE Open Vol. 11, No. 3 ( 2021-07), p. 215824402110475-
    Details
    In: SAGE Open, SAGE Publications, Vol. 11, No. 3 ( 2021-07), p. 215824402110475-
    Abstract: Drawing on motivated information processing theory, this study examined and compared the mechanism of prosocial motivation and intrinsic motivation on turnover intention among public and private employees. A valid sample of 328 public and private respondents was selected from the responses to the module of the International Social Survey Programme (ISSP) in the 2015 Chinese General Survey. The t-test was used to examine the differences in prosocial motivation, intrinsic motivation, and turnover intention through SPSS, and the methods of multigroup structural equation modeling and bootstrapping were adopted to examine and compare the mediation effects through AMOS. The results indicated that there were significant differences in prosocial motivation, intrinsic motivation, and turnover intention between public and private employees. Additionally, the indirect effects of prosocial motivation and intrinsic motivation on turnover intention were significantly mediated by affective commitment and then job satisfaction. There were significant public-private differences in the mediation mechanism. The findings suggest the chain mediation mechanism that prosocial motivation and intrinsic motivation are critical in facilitating organizational commitment, enhancing job satisfaction, and reducing turnover intention. This research contributes to a better understanding of the motivational mechanisms impacting turnover intention in the Chinese indigenous context, and suggests that so-called “good soldiers” and “good aspirants” are more likely to emerge in the public sector and remain in the public sector organizations.
    Type of Medium: Online Resource
    ISSN: 2158-2440 , 2158-2440
    URL: Article
    DOI: 10.1177/21582440211047567
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2628279-3
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  • 6
    Online Resource
    Online Resource
    High Glucose Induces Sumoylation of Smad4 via SUMO2/3 in Mesangial Cells
    Hindawi Limited ; 2014
    In:  BioMed Research International Vol. 2014 ( 2014), p. 1-10
    Details
    In: BioMed Research International, Hindawi Limited, Vol. 2014 ( 2014), p. 1-10
    Abstract: Recent studies have shown that sumoylation is a posttranslational modification involved in regulation of the transforming growth factor- β (TGF- β ) signaling pathway, which plays a critical role in renal fibrosis in diabetic nephropathy (DN). However, the role of sumoylation in the regulation of TGF- β signaling in DN is still unclear. In the present study, we investigated the expression of SUMO (SUMO1 and SUMO2/3) and Smad4 and the interaction between SUMO and Smad4 in cultured rat mesangial cells induced by high glucose. We found that SUMO1 and SUMO2/3 expression was significantly increased in the high glucose groups compared to the normal group P 〈 0.05 . Smad4 and fibronectin (FN) levels were also increased in the high glucose groups in a dose-dependent manner. Coimmunoprecipitation and confocal laser scanning revealed that Smad4 interacted and colocalized with SUMO2/3, but not with SUMO1 in mesangial cells. Sumoylation (SUMO2/3) of Smad4 under high glucose condition was strongly enhanced compared to normal control P 〈 0.05 . These results suggest that high glucose may activate TGF- β /Smad signaling through sumoylation of Samd4 by SUMO2/3 in mesangial cells.
    Type of Medium: Online Resource
    ISSN: 2314-6133 , 2314-6141
    URL: Article
    DOI: 10.1155/2014/782625
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2014
    detail.hit.zdb_id: 2698540-8
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  • 7
    Online Resource
    Online Resource
    High Glucose and Lipopolysaccharide Prime NLRP3 Inflammasome via ROS/TXNIP Pathway in Mesangial Cells
    Hindawi Limited ; 2016
    In:  Journal of Diabetes Research Vol. 2016 ( 2016), p. 1-11
    Details
    In: Journal of Diabetes Research, Hindawi Limited, Vol. 2016 ( 2016), p. 1-11
    Abstract: While inflammation is considered a central component in the development in diabetic nephropathy, the mechanism remains unclear. The NLRP3 inflammasome acts as both a sensor and a regulator of the inflammatory response. The NLRP3 inflammasome responds to exogenous and endogenous danger signals, resulting in cleavage of procaspase-1 and activation of cytokines IL-1 β , IL-18, and IL-33, ultimately triggering an inflammatory cascade reaction. This study observed the expression of NLRP3 inflammasome signaling stimulated by high glucose, lipopolysaccharide, and reactive oxygen species (ROS) inhibitor N-acetyl-L-cysteine in glomerular mesangial cells, aiming to elucidate the mechanism by which the NLRP3 inflammasome signaling pathway may contribute to diabetic nephropathy. We found that the expression of thioredoxin-interacting protein (TXNIP), NLRP3, and IL-1 β was observed by immunohistochemistry in vivo. Simultaneously, the mRNA and protein levels of TXNIP, NLRP3, procaspase-1, and IL-1 β were significantly induced by high glucose concentration and lipopolysaccharide in a dose-dependent and time-dependent manner in vitro. This induction by both high glucose and lipopolysaccharide was significantly inhibited by N-acetyl-L-cysteine. Our results firstly reveal that high glucose and lipopolysaccharide activate ROS/TXNIP/ NLRP3/IL-1 β inflammasome signaling in glomerular mesangial cells, suggesting a mechanism by which inflammation may contribute to the development of diabetic nephropathy.
    Type of Medium: Online Resource
    ISSN: 2314-6745 , 2314-6753
    URL: Article
    DOI: 10.1155/2016/6973175
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2016
    detail.hit.zdb_id: 2711897-6
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  • 8
    Online Resource
    Online Resource
    “I didn’t want to do, but I am happy to now!” Affect, voice and in-role performance
    Emerald ; 2021
    In:  Kybernetes Vol. 50, No. 5 ( 2021-05-03), p. 1467-1482
    Details
    In: Kybernetes, Emerald, Vol. 50, No. 5 ( 2021-05-03), p. 1467-1482
    Abstract: Previous research has examined the effects of discrete affects on voice; however, the role of trait and state affects in voice literature has received little attention. This study aims to address this important issue from a conservation of resources perspective, by exploring the influence of daily positive affect and emotional resistance to change on the voice of employees and their resulting work outcomes. Design/methodology/approach The study collected data about 285 daily episodes from 57 employees over five consecutive days, using an experience sampling method (ESM) through mobile surveys. The study found that emotional resistance to change was negatively related to employee voice and in-role performance. Findings Voice mediated the negative relationship between emotional resistance to change and in-role performance. The study also found that daily positive affect buffered the negative effects of emotional resistance to change on voice. Originality/value These findings extend the research concerning affect and voice; the study provides integrative insight into how affect dynamically influences organizations.
    Type of Medium: Online Resource
    ISSN: 0368-492X , 0368-492X
    URL: Article
    DOI: 10.1108/K-01-2020-0007
    Language: English
    Publisher: Emerald
    Publication Date: 2021
    detail.hit.zdb_id: 1479781-1
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  • 9
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    Online Resource
    Mixed matrix membrane containing metal oxide nanosheets for efficient CO2 separation
    Elsevier BV ; 2021
    In:  Green Chemical Engineering Vol. 2, No. 1 ( 2021-03), p. 132-143
    Details
    In: Green Chemical Engineering, Elsevier BV, Vol. 2, No. 1 ( 2021-03), p. 132-143
    Type of Medium: Online Resource
    ISSN: 2666-9528
    URL: Article
    DOI: 10.1016/j.gce.2020.11.009
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2021
    detail.hit.zdb_id: 3072980-4
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  • 10
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    Online Resource
    The ambidextrous and differential effects of directive versus empowering leadership: a study from project context
    Emerald ; 2021
    In:  Leadership & Organization Development Journal Vol. 42, No. 3 ( 2021-04-20), p. 348-369
    Details
    In: Leadership & Organization Development Journal, Emerald, Vol. 42, No. 3 ( 2021-04-20), p. 348-369
    Abstract: This study investigated the differential effects of empowering leadership and directive leadership in projects. Moreover, how the complex interplay between empowering and directive leadership styles influences both leader–member exchange and project performance was also explored. Design/methodology/approach Polynomial regression analysis and response surface modeling were applied to analyze 161 matched data collected from project members and managers worked in different projects located in China. Findings Four leadership styles were identified, i.e. ambidextrous, delegating, directive and laissez-faire styles. These may be combined with empowering and directive leadership. With regard to (in)congruence, leader–member exchange and project performance improved with ambidextrous style as a form of high–high congruence between empowering and directive leadership compared with laissez-faire style (i.e. low–low congruence). Results were better when a delegating style was combined with empowering leadership at a high level compared with the combination of directive style as directive leadership at a high level. Leader–member exchange was identified to exert a mediating role of the (in)congruence on project performance. Originality/value This study confirmed the contingent viewpoint of leadership by identifying distinct leadership styles applied in projects. Furthermore, the co-existence of empowering leadership and directive leadership was examined, and the underlying mechanism between the (in)congruence of empowering and directive leadership and project performance was identified.
    Type of Medium: Online Resource
    ISSN: 0143-7739
    URL: Article
    DOI: 10.1108/LODJ-12-2019-0509
    Language: English
    Publisher: Emerald
    Publication Date: 2021
    detail.hit.zdb_id: 2021219-7
    SSG: 3,2
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