In:
Applied Physiology, Nutrition, and Metabolism, Canadian Science Publishing, Vol. 43, No. 3 ( 2018-03), p. 221-226
Abstract:
We determined the effects of repeated sprint exercise under normoxic and hypoxic conditions on serum hepcidin levels. Ten male athletes (age: 20.9 ± 0.3 years; height: 175.7 ± 6.0 cm; weight: 67.3 ± 6.3 kg) performed 2 exercise trials under normoxic (NOR; fraction of inspiratory oxygen (FiO 2 ): 20.9%) or hypoxic conditions (HYPO; FiO 2 : 14.5%). The exercise consisted of 3 sets of 5 × 6 s of maximal pedaling (30-s rest periods between sprints, 10-min rest periods between sets). Blood samples were collected before exercise, immediately after exercise, and 1 and 3 h after exercise. Serum hepcidin levels were significantly elevated after exercise in both trials (both P 〈 0.01), with no significant difference between the trials. The postexercise blood lactate levels were significantly higher in the HYPO than the NOR (P 〈 0.05). Both trials caused similar increases in plasma interleukin-6 and serum iron levels (P 〈 0.001), with no significant difference between the trials. A significant interaction (trial × time) was apparent in terms of serum erythropoietin (EPO) levels (P = 0.003). The EPO level was significantly higher in the HYPO than the NOR at 3 h after exercise (P 〈 0.05). In conclusion, repeated sprint exercise significantly increased serum hepcidin levels to similar extent in 2 trials, despite differences in the inspired oxygen concentrations during both the exercise and the 3-h postexercise period.
Type of Medium:
Online Resource
ISSN:
1715-5312
,
1715-5320
DOI:
10.1139/apnm-2017-0418
Language:
English
Publisher:
Canadian Science Publishing
Publication Date:
2018
SSG:
31
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