In:
Helvetica Chimica Acta, Wiley, Vol. 70, No. 8 ( 1987-12-16), p. 2098-2109
Abstract:
(−)‐(4 S ,16 S )‐8, 12‐bis[de(2‐carboxyethyl)]mesourobilin‐IIIα hydrochloride ( 8 ) has been synthesized from the enantiomerically pure 1,4,5,10‐tetrahydro‐1‐oxodipyrrin‐9‐carboxylic‐acid precursor 6a whose absolute configuration was determined by X‐ray diffraction analysis of the N ‐[( S )‐1‐(1‐naphthyl)ethyl] carboxamide 7b . The present results prove unequivocally that an ( S , S )‐configurated urobilin chromophore displays a negative Cotton effect in the VIS absorption range. However, the helicity of the inherently dissymmetric chromophore remains undetermined.
Type of Medium:
Online Resource
ISSN:
0018-019X
,
1522-2675
DOI:
10.1002/hlca.19870700815
Language:
English
Publisher:
Wiley
Publication Date:
1987
detail.hit.zdb_id:
74-7
detail.hit.zdb_id:
1475013-2
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