In:
Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 146, No. Suppl_1 ( 2022-11-08)
Abstract:
Introduction Sodium abnormalities are commonly associated with congestive heart failure (CHF). The main objective of this study is to analyze the impact of hyponatremia vs. hypernatremia on in-hospital outcomes in patients admitted with CHF Methods The National inpatient sample (NIS) data from 2017 to 2018 were queried using International Classification of Diseases 10 (ICD-10-CM) codes E871 and E870. Demographics and hospital characteristics were compared along with In-hospital mortality, length of stay (LOS), and total charge. The outcomes were measured using linear and logistic regression models to adjust the odds ratio for confounders. Results: A total of 350,144 patients with heart failure as a primary diagnosis (42% systolic and 32% diastolic HF) were included in the study. Among them, 37,129 (10.7%) had hyponatremia while 5839 (1.8%) had hypernatremia. In-hospital mortality rates were significantly higher with an adjusted odds ratio (OR) of 2.78 (p 〈 0.001) among hypernatremia patients. Mean length of stay (LOS) was also high among hypernatremia patients (12.3 vs 8 days), with an adjusted odds ratio of 4.89 (p-value 〈 0.001). Similarly, mean total charges were higher in the hypernatremia group (175,632$ vs 91,022 $). Notably, hypernatremia was associated with more hemorrhage complications (OR-6.35, p 〈 0.001). Conclusions: Even though hypernatremia is less frequent than hyponatremia among CHF patients, it is associated with significantly higher mortality, LOS, and total charges than hyponatremia.
Type of Medium:
Online Resource
ISSN:
0009-7322
,
1524-4539
DOI:
10.1161/circ.146.suppl_1.14592
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2022
detail.hit.zdb_id:
1466401-X
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