In:
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, Vol. 43, No. 2 ( 1999-02), p. 393-396
Abstract:
Twelve SHV-type extended-spectrum β-lactamase (ESBL)-producing Escherichia coli lac mutant isolates were recovered in October 1997 from 11 patients of the neonatal ward in a Warsaw hospital. The outbreak was clonal; however, some of the isolates expressed a much higher level of resistance to several β-lactam antibiotics, including expanded-spectrum cephalosporins. This phenotype has been attributed to β-lactamase hyperproduction correlating with the multiplication of ESBL gene copies, as was demonstrated for representative isolates.
Type of Medium:
Online Resource
ISSN:
0066-4804
,
1098-6596
DOI:
10.1128/AAC.43.2.393
Language:
English
Publisher:
American Society for Microbiology
Publication Date:
1999
detail.hit.zdb_id:
1496156-8
SSG:
12
SSG:
15,3
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