In:
Psychological Reports, SAGE Publications, Vol. 40, No. 3_suppl ( 1977-06), p. 1339-1344
Abstract:
An infant rhesus monkey was separated from its mother at 90 days of age, housed individually, and at 120 days of age placed on a purified low protein diet containing 3.5% casein by weight. To enhance the effects of protein-calorie malnutrition, a protein-deficient diet containing 2.0% casein by weight was introduced at 415 days of age. When compared with other animals on an identical dietary regime, the subject manifested a reduced intake of food and a marked decrease in weight gain. Clinical symptomatology analogous to human kwashiorkor progressively developed into an acute phase as a result of protein deficiency and included: brittle, depigmented, and sparse hair; chronic diarrhea; dermatitis as “flaky-paint rash” on the extremities and “moist groin rash;” edema of the face and extremities; hypoalbuminemia; hypoproteinemia; retardation of growth and physical development; and wasting of muscle tissue. Within 172 days following the dietary shift from 3.5% to 2.0% casein, a terminal state was evidenced.
Type of Medium:
Online Resource
ISSN:
0033-2941
,
1558-691X
DOI:
10.2466/pr0.1977.40.3c.1339
Language:
English
Publisher:
SAGE Publications
Publication Date:
1977
detail.hit.zdb_id:
2066930-6
SSG:
5,2
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