In:
Nuclear Medicine Communications, Ovid Technologies (Wolters Kluwer Health), Vol. 40, No. 11 ( 2019-11), p. 1130-1137
Abstract:
The use of cadmium–zinc–telluride-based scanners may increase the clinical feasibility of simultaneous dual-isotope imaging. In the current study, we sought to investigate a potential acquisition time in simultaneous 99m Tc-tetrofosmin/ 123 I-β-methyl- p -iodophenyl pentadecanoic acid dual-isotope imaging using a Discovery NM/CT 670 cadmium–zinc–telluride. Methods Simultaneous 99m Tc-tetrofosmin/ 123 I-β-methyl- p -iodophenyl pentadecanoic acid dual-isotope imaging was performed in 29 patients who had undergone primary percutaneous coronary intervention for acute myocardial infarction. Referenced images with an acquisition time of 65 s/view (16.25 min) were reframed to produce images with acquisition times of 33, 16, and 8 s/view. The values for the quantitative-gated single-photon emission computed tomography (SPECT) and the quantitative perfusion SPECT were compared. Results The quantitative-gated SPECT values for images with 33, 16, and 8 s/views showed good consistency with those for 65 s/view (the lower 95% confidence intervals for the intraclass correlation were ≥0.80). The quantitative perfusion SPECT values for 99m Tc-tetrofosmin images with 33, 16, and 8 s/views also showed good consistency with those for 65 s/view; however, the quantitative perfusion SPECT values for 123 I-β-methyl- p -iodophenyl pentadecanoic acid images with an acquisition time of 8 s/view were not consistent with the reference acquisition time of 65 s/view. Conclusions The quantitative-gated SPECT and quantitative perfusion SPECT values obtained from images with shorter acquisition times correlated with the values obtained from images with a reference acquisition time of 65 s/view; however, tracer-specific predisposition should be considered. These findings suggest that it is possible to reduce acquisition time when performing simultaneous 99m Tc-tetrofosmin/ 123 I-β-methyl- p -iodophenyl pentadecanoic acid dual-tracer imaging with the novel cadmium–zinc–telluride scanner.
Type of Medium:
Online Resource
ISSN:
0143-3636
DOI:
10.1097/MNM.0000000000001084
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2019
detail.hit.zdb_id:
2028880-3
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